Hyun‐Jin Tae
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View article: 3D-Printed Autologous Micronized Adipose Patch Graft for Skin Regeneration in a Dog with a Refractory Skin Defect after a Soft Tissue Sarcoma Resection
3D-Printed Autologous Micronized Adipose Patch Graft for Skin Regeneration in a Dog with a Refractory Skin Defect after a Soft Tissue Sarcoma Resection Open
View article: Renoprotective mechanisms of bioconverted wild-simulated ginseng: mitigating oxidative stress, inflammation, and apoptosis to protect against ischemic renal injury via Nrf2/HO-1/NF-κB/caspase-3 signaling
Renoprotective mechanisms of bioconverted wild-simulated ginseng: mitigating oxidative stress, inflammation, and apoptosis to protect against ischemic renal injury via Nrf2/HO-1/NF-κB/caspase-3 signaling Open
View article: Morphometric studies on the skeleton of hind limb of Korean native steers with postnatal development
Morphometric studies on the skeleton of hind limb of Korean native steers with postnatal development Open
View article: Macluraparishin C Enhances Neuroprotection Against Oxidative Stress-Induced Neurodegeneration by Activating the Antioxidant/MAPK Signaling Pathway
Macluraparishin C Enhances Neuroprotection Against Oxidative Stress-Induced Neurodegeneration by Activating the Antioxidant/MAPK Signaling Pathway Open
View article: Oral treatment with Rosa multiflora fructus extract modulates mast cells in canine atopic dermatitis
Oral treatment with Rosa multiflora fructus extract modulates mast cells in canine atopic dermatitis Open
Introduction Canine atopic dermatitis is a hereditary, often pruritic, and predominantly T-cell-driven inflammatory skin disease involving an interplay between skin barrier abnormalities and allergen sensitization. However, progress in dev…
View article: The enhanced stability of ring pin–based tension band wiring in canine transverse patellar fracture models
The enhanced stability of ring pin–based tension band wiring in canine transverse patellar fracture models Open
Objective To evaluate the tensile strength and biomechanical properties of the tension band wire technique using a ring pin in a canine patellar transverse fracture model and to compare it with conventional tension band wire techniques. Me…
View article: Morphology of subclavian artery branching patterns in cats (<i>Felis catus</i>)
Morphology of subclavian artery branching patterns in cats (<i>Felis catus</i>) Open
This study offers a detailed analysis of the SB branching patterns in cats, highlighting significant intraspecific variation and distinctive branching order. These findings enhance our understanding of vascular diversity among carnivores a…
View article: Expression and delivery of HA1-M2e antigen using an innovative attenuated Salmonella–mediated delivery system confers promising protection against H9N2 avian influenza challenge
Expression and delivery of HA1-M2e antigen using an innovative attenuated Salmonella–mediated delivery system confers promising protection against H9N2 avian influenza challenge Open
View article: Intracellular Survival and Pathogenicity Modulation of Salmonella Lon, CpxR, and RfaL Mutants Used as Live Bacterial Vectors under Abiotic Stress, Unveiling the Link between Stress Response and Virulence in Epithelial Cells
Intracellular Survival and Pathogenicity Modulation of Salmonella Lon, CpxR, and RfaL Mutants Used as Live Bacterial Vectors under Abiotic Stress, Unveiling the Link between Stress Response and Virulence in Epithelial Cells Open
In the current study, two Salmonella Typhimurium strains, JOL 912 and JOL 1800, were engineered from the wild-type JOL 401 strain through in-frame deletions of the lon and cpxR genes, with JOL 1800 also lacking rfaL. These deletions signif…
View article: Establishment of an experimental model of ovalbumin-induced atopic dermatitis in canines
Establishment of an experimental model of ovalbumin-induced atopic dermatitis in canines Open
Introduction A reliable standard model is required to evaluate the efficacy of new drugs for companion animals, especially dogs. Canine atopic dermatitis (cAD), also known as allergic inflammatory skin disease, is a common condition. Curre…
View article: Morphology of the aortic arch branching pattern in raccoon dogs (<i>Nyctereutes procyonoides</i>, Gray, 1834)
Morphology of the aortic arch branching pattern in raccoon dogs (<i>Nyctereutes procyonoides</i>, Gray, 1834) Open
The AA branching pattern in raccoon dogs exhibited various branching patterns with both similarities and differences compared to other carnivores.
View article: Solitary patent ductus arteriosus in a Japanese macaque (<i>Macaca fuscata</i>)
Solitary patent ductus arteriosus in a Japanese macaque (<i>Macaca fuscata</i>) Open
This case study involved a 9-year-old male Japanese macaque that had resided in a zoo in Busan, Korea for exhibition purposes from 2015 to 2021.The macaque weighed 11 kg.The macaque was accommodated in an outdoor enclosure, thoughtfully eq…
View article: Veronica persica ameliorates acetaminophen-induced murine hepatotoxicity via attenuating oxidative stress and inflammation
Veronica persica ameliorates acetaminophen-induced murine hepatotoxicity via attenuating oxidative stress and inflammation Open
Excess acetaminophen (APAP) commonly causes severe acute liver injury (ALI), characterized by oxidative stress, pro-inflammatory responses, and hepatocyte damage. Veronica persica (VP) is a traditional medicine with antioxidant and anti-in…
View article: Electrospun Manganese-Based Metal–Organic Frameworks for MnO<sub><i>x</i></sub> Nanostructures Embedded in Carbon Nanofibers as a High-Performance Nonenzymatic Glucose Sensor
Electrospun Manganese-Based Metal–Organic Frameworks for MnO<sub><i>x</i></sub> Nanostructures Embedded in Carbon Nanofibers as a High-Performance Nonenzymatic Glucose Sensor Open
Material-specific electrocatalytic activity and electrode design are essential factors in evaluating the performance of electrochemical sensors. Herein, the technique described involves electrospinning manganese-based metal-organic framewo…
View article: The Effect of Olanzapine through Antioxidant and Anti-Inflammation on the Hippocampus in the Asphyxial Cardiac Arrest Rat Model
The Effect of Olanzapine through Antioxidant and Anti-Inflammation on the Hippocampus in the Asphyxial Cardiac Arrest Rat Model Open
Introduction: Cardiac arrest (CA) often leads to severe brain damage, resulting in neurological disorders and high mortality rates. Hypothermia treatment (HT) is commonly used in clinical practice after CA/cardio-pulmonary resuscitation (C…
View article: Morphological and morphometric study of the scapulae of Korean wild deer
Morphological and morphometric study of the scapulae of Korean wild deer Open
Korean water deer ( Hydropotes inermis argyropus ; Heude, 1884) and Siberian roe deer ( Capreolus pygargus ; Pallas, 1771) are Korean wild deer classified in the tribe Capreolini. C. pygargus in Korea were previously considered a single sp…
View article: Plum-Derived Exosome-like Nanovesicles Induce Differentiation of Osteoblasts and Reduction of Osteoclast Activation
Plum-Derived Exosome-like Nanovesicles Induce Differentiation of Osteoblasts and Reduction of Osteoclast Activation Open
Osteoblasts and osteoclasts play crucial roles in bone formation and bone resorption. We found that plum-derived exosome-like nanovesicles (PENVs) suppressed osteoclast activation and modulated osteoblast differentiation. PENVs increased t…
View article: Solitary patent ductus arteriosus in a Japanese macaque (Macaca fuscata): a case report and genetic investigation
Solitary patent ductus arteriosus in a Japanese macaque (Macaca fuscata): a case report and genetic investigation Open
We present the first report of solitary patent ductus arteriosus (PDA) without associated cardiovascular anomalies in a Japanese macaque ( Macaca fuscata ). The macaque showed no signs of PDA during its lifetime and lived for 9 years until…
View article: Risperidone Administration Attenuates Renal Ischemia and Reperfusion Injury following Cardiac Arrest by Antiinflammatory Effects in Rats
Risperidone Administration Attenuates Renal Ischemia and Reperfusion Injury following Cardiac Arrest by Antiinflammatory Effects in Rats Open
Multi-organ dysfunction following cardiac arrest is associated with poor outcome as well as high mortality. The kidney, one of major organs in the body, is susceptible to ischemia and reperfusion; however, there are few studies on renal is…
View article: Prevalence, Seroprevalence and Risk Factors of Avian Influenza in Wild Bird Populations in Korea: A Systematic Review and Meta-Analysis
Prevalence, Seroprevalence and Risk Factors of Avian Influenza in Wild Bird Populations in Korea: A Systematic Review and Meta-Analysis Open
Since the first recorded outbreak of the highly pathogenic avian influenza (HPAI) virus (H5N1) in South Korea in 2003, numerous sporadic outbreaks have occurred in South Korean duck and chicken farms, all of which have been attributed to a…
View article: Therapeutic Hypothermia after Cardiac Arrest Attenuates Hindlimb Paralysis and Damage of Spinal Motor Neurons and Astrocytes through Modulating Nrf2/HO-1 Signaling Pathway in Rats
Therapeutic Hypothermia after Cardiac Arrest Attenuates Hindlimb Paralysis and Damage of Spinal Motor Neurons and Astrocytes through Modulating Nrf2/HO-1 Signaling Pathway in Rats Open
Cardiac arrest (CA) and return of spontaneous circulation (ROSC), a global ischemia and reperfusion event, lead to neuronal damage and/or death in the spinal cord as well as the brain. Hypothermic therapy is reported to protect neurons fro…
View article: Changes of antioxidant enzymes in the kidney after cardiac arrest in the rat model
Changes of antioxidant enzymes in the kidney after cardiac arrest in the rat model Open
Globally, cardiac arrest (CA) is a leading cause of death and disability. Asphyxial CA (ACA)-induced kidney damage is a crucial factor in reducing the survival rate. The purpose of this study was to investigate the role of antioxidant enzy…
View article: Anti-Inflammatory Effects of <i>Aralia elata</i> Extract Against Dextran Sodium Sulfate-Induced Colitis in Mice and Raw 264.7 Macrophage Cells Exposed to Lipopolysaccharide: First Report
Anti-Inflammatory Effects of <i>Aralia elata</i> Extract Against Dextran Sodium Sulfate-Induced Colitis in Mice and Raw 264.7 Macrophage Cells Exposed to Lipopolysaccharide: First Report Open
Aralia elata (AE) is an anti-inflammatory, polyphenolic containing medicinal plant. However, little is known about AE and its application to ulcerative colitis (UC). This study aimed to confirm AE extract's antioxidant and anti-inflammator…
View article: Olanzapine Ameliorates Ischemic Stroke-like Pathology in Gerbils and H2O2-Induced Neurotoxicity in SH-SY5Y Cells via Inhibiting the MAPK Signaling Pathway
Olanzapine Ameliorates Ischemic Stroke-like Pathology in Gerbils and H2O2-Induced Neurotoxicity in SH-SY5Y Cells via Inhibiting the MAPK Signaling Pathway Open
Olanzapine (OLNZ) is used to treat psychotic disorders. To look into the neurological basis of this phenomenon, we investigated the neuroprotective effects of OLNZ in gerbils and SH-SY5Y cells. Gerbils were subjected to transient global ce…
View article: Fermented Mentha arvensis administration provides neuroprotection against transient global cerebral ischemia in gerbils and SH-SY5Y cells via downregulation of the MAPK signaling pathway
Fermented Mentha arvensis administration provides neuroprotection against transient global cerebral ischemia in gerbils and SH-SY5Y cells via downregulation of the MAPK signaling pathway Open
View article: Anti-inflammatory effects of the Aralia elata and Cirsium japonicum in Raw264.7 cells and in vivo colitis model in mice and dogs
Anti-inflammatory effects of the Aralia elata and Cirsium japonicum in Raw264.7 cells and in vivo colitis model in mice and dogs Open
Ulcerative colitis (UC) is a severe inflammatory disease that has spread throughout the world. Cirsium japonicum (CJ) and Aralia elata (AE) are natural herbs with potent antioxidative antidiabetics and anti-inflammatory effects. In this in…
View article: Olanzapine-Induced Therapeutic Hypothermia Attenuates Renal Injury in Rats after Asphyxial Cardiac Arrest and Resuscitation
Olanzapine-Induced Therapeutic Hypothermia Attenuates Renal Injury in Rats after Asphyxial Cardiac Arrest and Resuscitation Open
Return of spontaneous circulation (ROSC) through cardiopulmonary resuscitation (CPR) after cardiac arrest (CA) causes post-cardiac arrest syndrome (PCAS) due to dysfunction in various organs, which provokes acute kidney injury because of r…
View article: Asfiksiyal Kardiyak Arrestli Rat Modelinde Böbrek Histopatolojisi ve Tümör Nekrozis Faktör-α Ekspresyonu
Asfiksiyal Kardiyak Arrestli Rat Modelinde Böbrek Histopatolojisi ve Tümör Nekrozis Faktör-α Ekspresyonu Open
Multiple organ injuries in patients with post cardiac arrest syndrome (PCAS) after cardiac arrest (CA) is associated with mortality. Among multiple organ injuries after return of spontaneous circulation (ROSC), renal dysfunction can lead t…
View article: Effect of therapeutic hypothermia against renal injury in a rat model of asphyxial cardiac arrest: Α focus on the survival rate, pathophysiology and antioxidant enzymes
Effect of therapeutic hypothermia against renal injury in a rat model of asphyxial cardiac arrest: Α focus on the survival rate, pathophysiology and antioxidant enzymes Open
Although multi‑organ dysfunction is associated with the survival rate following cardiac arrest (CA), the majority of studies to date have focused on hearts and brains, and few studies have considered renal failure. The objective of the pre…
View article: Therapeutic Effects of Risperidone against Spinal Cord Injury in a Rat Model of Asphyxial Cardiac Arrest: A Focus on Body Temperature, Paraplegia, Motor Neuron Damage, and Neuroinflammation
Therapeutic Effects of Risperidone against Spinal Cord Injury in a Rat Model of Asphyxial Cardiac Arrest: A Focus on Body Temperature, Paraplegia, Motor Neuron Damage, and Neuroinflammation Open
Cardiac arrest (CA) causes severe spinal cord injury and evokes spinal cord disorders including paraplegia. It has been reported that risperidone, an antipsychotic drug, effectively protects neuronal cell death from transient ischemia inju…