Alfonso Ielasi
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View article: Transcatheter Aortic Valve‐in‐Valve Implantation for Failing Stentless Bioprosthetic Aortic Valves: An International Multicentre Retrospective Analysis
Transcatheter Aortic Valve‐in‐Valve Implantation for Failing Stentless Bioprosthetic Aortic Valves: An International Multicentre Retrospective Analysis Open
Background Valve‐in‐valve aortic valve implantation (ViV‐TAVI) offers a less invasive treatment option for patients with a failing surgical bioprosthesis, avoiding the need for redo surgery. ViV‐TAVI within a stentless bioprosthetic valve …
Advancements in Pulmonary Embolism Management: Current Approaches and Future Directions Open
Pulmonary embolism (PE) is one of the leading causes of cardiovascular mortality, with a high 30-day mortality rate. Despite clear treatment guidelines based on patient risk profiles, evidence suggests a discrepancy between clinical practi…
Effectiveness of cerebral embolic protection during transcatheter aortic valve replacement: A systematic review and meta-analysis of randomized trials Open
CEP devices do not significantly reduce short-term stroke or major complications after TAVR. However, given the prevalence of silent cerebral ischemia, further studies are needed to assess long-term neurological outcomes and identify high-…
View article: Impact of Valve Frame Height on PCI Outcomes After TAVR
Impact of Valve Frame Height on PCI Outcomes After TAVR Open
In current practice, long-term outcomes after PCI in TAVR patients do not appear to be significantly different between those receiving SFVs and TFVs. Future investigations with newer generation valves and refined implantation techniques ar…
View article: Clinical outcomes of percutaneous coronary interventions after transcatheter aortic valve replacement
Clinical outcomes of percutaneous coronary interventions after transcatheter aortic valve replacement Open
Aims The number of patients undergoing percutaneous coronary interventions (PCI) after transcatheter aortic valve replacement (TAVR) is expected to increase, but their prognosis remains poorly understood. Methods and results Consecutive PC…
View article: Comparative 30-day echocardiographic outcomes of Myval vs. Sapien and Evolut THVs: insights from LANDMARK trial
Comparative 30-day echocardiographic outcomes of Myval vs. Sapien and Evolut THVs: insights from LANDMARK trial Open
Aims Several factors, including device design, annulus size, and sizing strategies, influence transcatheter heart valve (THV) haemodynamic outcomes in patients with aortic stenosis (AS). This sub-study evaluates early (30-day) echocardiogr…
Sirolimus-coated balloon in young versus old patients with coronary artery disease: a sub-analysis of the EASTBOURNE study Open
To the Editor, Premature coronary artery disease (CAD) affects 7%-10% of patients younger than 55 years, leading to reduced quality of life and a significant risk of adverse events.1 Percutaneous coronary intervention (PCI) with drug-eluti…
View article: Combined Percutaneous Left Atrial Appendage Closure and Mitral Transcatheter Edge‐to‐Edge Repair: Current Evidence and Practical Considerations
Combined Percutaneous Left Atrial Appendage Closure and Mitral Transcatheter Edge‐to‐Edge Repair: Current Evidence and Practical Considerations Open
Atrial fibrillation commonly coexists with severe mitral regurgitation, complicating management by necessitating long‐term anticoagulation, with its associated bleeding risk. The combined approach of percutaneous left atrial appendage clos…
View article: Transcatheter Aortic Valve Implantation in Patients with Pure Non-Calcified Aortic Regurgitation
Transcatheter Aortic Valve Implantation in Patients with Pure Non-Calcified Aortic Regurgitation Open
Background: While transcatheter aortic valve implantation (TAVI) is a well-established therapy for elderly patients with aortic stenosis, its role in treating pure non-calcified aortic regurgitation (AR) remains limited due to anatomical c…
View article: Long‐Term Durability of Transcatheter Aortic Valves in Patients With Bicuspid Aortic Stenosis
Long‐Term Durability of Transcatheter Aortic Valves in Patients With Bicuspid Aortic Stenosis Open
Background Data concerning the long‐term durability of transcatheter aortic valves (TAVs) in patients with bicuspid aortic stenosis (AS) are lacking. Aims The study aims to report data on long‐term valve durability following transcatheter …
Performance of drug-coated balloons in East Asian and Caucasian patients: a post hoc analysis of the EASTBOURNE Registry Open
In this subgroup analysis of the EASTBOURNE Registry comparing patients of Caucasian versus East Asian origin treated with SCBs, there were higher incidences of TLR but less bleeding in the Caucasian population compared to East Asian patie…
View article: Effectiveness and Safety of Myval Versus Other Transcatheter Valves in Patients Undergoing TAVI: A Meta‐Analysis
Effectiveness and Safety of Myval Versus Other Transcatheter Valves in Patients Undergoing TAVI: A Meta‐Analysis Open
Transcatheter aortic valve implantation (TAVI) has changed the treatment of aortic stenosis. The Myval transcatheter heart valve (THV), a novel balloon‐expandable THV, has shown promising outcomes. Our aim is to compare the comparative saf…
First Transcatheter Valve-in-Valve Implantation With Myval Octacor Into a Failed Biological Prosthetic Aortic Valve in Serbia Open
The natural progression of bioprosthetic valve degeneration over time requires further interventions for those experiencing symptomatic prosthesis dysfunction. Transcatheter aortic valve replacement (TAVR) emerges as a promising therapeuti…
View article: Early outcomes of the novel Myval THV series compared to SAPIEN THV series and Evolut THV series in individuals with severe aortic stenosis
Early outcomes of the novel Myval THV series compared to SAPIEN THV series and Evolut THV series in individuals with severe aortic stenosis Open
ClinicalTrials.gov: NCT04275726; EudraCT number 2020-000,137-40.
View article: Long-term prognostic impact of the left anterior descending coronary artery as the STEMI-related culprit vessel: subanalysis of the EXAMINATION-EXTEND trial
Long-term prognostic impact of the left anterior descending coronary artery as the STEMI-related culprit vessel: subanalysis of the EXAMINATION-EXTEND trial Open
Introduction and objectives: There is limited data on the impact of the culprit vessel on very long-term outcomes after ST-elevation myocardial infarction (STEMI). The aim was to analyze the impact of the left anterior descending coronary …
Five-year clinical outcomes of STEMI patients treated with a pre-specified bioresorbable vascular scaffold implantation technique: Final results of the BVS STEMI STRATEGY-IT Open
This study shows favorable 5-year outcomes for BVS in selected STEMI patients with an optimized implantation strategy. Prolonged DAPT further improved outcomes, emphasizing its role in reducing adverse events during scaffold resorption. Fu…
Performance of the Mammoth Balloon Catheter in Patients with Severe Aortic Valve Stenosis Undergoing Percutaneous Treatment Open
Background: Balloon aortic valvuloplasty (BAV) is currently used as pre-treatment for patients undergoing trans-catheter aortic valve replacement (TAVR) as well as a stand-alone option for subjects with significant contraindications to TAV…
Inter-ethnic heterogeneity in valvular morphology and aortopathy of a worldwide bicuspid aortic valve cohort referred for TAVR Open
Background Bicuspid aortic valve (BAV) represents one of the most common congenital heart disease. BAV stenosis tipycally occurs in younger, low-surgical risk patients compared to tricuspid aortic valves (TAV). With the predicted expansion…
Percutaneous Coronary Intervention before or after Transcatheter Aortic Valve Replacement: A Systematic Review and Meta-Analysis Involving 1531 Patients Open
Background: The optimal timing to perform percutaneous coronary interventions (PCIs) in patients undergoing transcatheter aortic valve replacement (TAVR) is not well established. In this meta-analysis, we aimed to compare the outcomes of p…
Clinical outcomes of the Myval transcatheter heart valve system in patients with severe aortic valve stenosis: a two-year follow-up observational study Open
Introduction Limited data exist on long-term follow-up of severe aortic stenosis (SAS) patients who have undergone transcatheter aortic valve implantation (TAVI) with a new generation, balloon expandable Myval transcatheter heart valve (TH…