Martı́ Pumarola
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View article: Anatomical and histological characterization of the filum terminale in dogs
Anatomical and histological characterization of the filum terminale in dogs Open
The filum terminale (FT) remains poorly characterized in the veterinary literature, limiting understanding of its role in spinal cord and nerve root pathologies such as tethered cord syndrome. This study aimed to establish baseline anatomi…
View article: Multiple spinal nerve sheath tumors in a dog resembling schwannomatosis in humans
Multiple spinal nerve sheath tumors in a dog resembling schwannomatosis in humans Open
A 7-y-old male neutered crossbreed dog was presented to a veterinary referral hospital with a 9-mo history of progressive non-ambulatory tetraparesis. A magnetic resonance imaging (MRI) study revealed multiple T2-weighted hyperintense intr…
View article: Pathology of <i>Clostridium colinum</i> infection in quail
Pathology of <i>Clostridium colinum</i> infection in quail Open
Clostridium colinum causes ulcerative enteritis in several avian species. The disease is particularly prevalent in quail, and it is therefore colloquially known as quail disease. The pathogenesis of the infection is poorly understood. A re…
View article: Cutaneous schwannoma and intense licking suggestive of neuropathic pruritus in a cat
Cutaneous schwannoma and intense licking suggestive of neuropathic pruritus in a cat Open
This report describes a cat with unusual neuropathic pruritus associated with a cutaneous schwannoma. A 12‐year‐old, neutered, male, European shorthair cat presented with intense licking on the medial aspect of the right hindlimb, partiall…
View article: Meningeal solitary fibrous tumour (hemangiopericytoma) in a dog
Meningeal solitary fibrous tumour (hemangiopericytoma) in a dog Open
A 6‐year‐old, male entire French Bulldog was presented for a 2‐month history of progressive ambulatory tetraparesis and occasional cervical pain. Neurological examination was consistent with a right‐sided C1–C5 myelopathy. Magnetic resonan…
View article: Immunohistochemical Expression of Tenascin-C in Canine Meningiomas
Immunohistochemical Expression of Tenascin-C in Canine Meningiomas Open
In humans, tenascin-C (TN-C) expression has been detected in more aggressive neoplasms of the central nervous system, such as gliomas and meningiomas. No study has analyzed the immune expression of TN-C in canine meningioma. The current st…
View article: Gliosarcoma associated with bilateral hippocampal sclerosis in a cat presenting complex partial seizures with orofacial involvement: A case report
Gliosarcoma associated with bilateral hippocampal sclerosis in a cat presenting complex partial seizures with orofacial involvement: A case report Open
Key Clinical Message Gliosarcoma, a rare cerebral neoplasm, has not been linked to hippocampal changes in cats. We report a case of complex partial seizures with orofacial involvement, revealing gliosarcoma concurrent with bilateral hippoc…
View article: Immunohistochemical Expression of PTEN in Canine Gliomas
Immunohistochemical Expression of PTEN in Canine Gliomas Open
Phosphatase and tensin homolog (PTEN) is a critical tumor suppressor gene with a vital role in regulating cell proliferation, migration, and survival. The loss of PTEN function, either by genetic alterations or decreased protein expression…
View article: Anatomical description of a new ligamentous supporting structure of the canine cranial cervical spinal cord
Anatomical description of a new ligamentous supporting structure of the canine cranial cervical spinal cord Open
The cranial cervical vertebral column carries a unique range of mobility with the addition of dorsal and ventral flexion and rotation. The denticulate ligaments provides support and protection of the spinal cord, but little is known of the…
View article: Granuloprival cerebellar cortical degeneration in a <scp>Yorkshire Terrier</scp> and <scp>Lagotto Romagnolo</scp> dog
Granuloprival cerebellar cortical degeneration in a <span>Yorkshire Terrier</span> and <span>Lagotto Romagnolo</span> dog Open
Granuloprival degeneration is an uncommon form of cerebellar cortical degeneration (CCD). A 3‐month‐old Yorkshire Terrier and a 7‐month‐old Lagotto Romagnolo dog were presented with a history of progressive cerebellar dysfunction including…
View article: Evaluation of in vitro intrinsic radiosensitivity and characterization of five canine high-grade glioma cell lines
Evaluation of in vitro intrinsic radiosensitivity and characterization of five canine high-grade glioma cell lines Open
Glioma is the most common primary brain tumor in dogs and predominantly affects brachycephalic breeds. Diagnosis relies on CT or MRI imaging, and the proposed treatments include surgical resection, chemotherapy, and radiotherapy depending …
View article: Clinical and imaging features of a feline lumbar myelopathy resembling ossification of the posterior longitudinal ligament in humans
Clinical and imaging features of a feline lumbar myelopathy resembling ossification of the posterior longitudinal ligament in humans Open
A 9‐year‐old, male, neutered Russian blue cat was presented for a 2‐week history of pelvic limb weakness and reluctance to jump and climb stairs. Neurological examination was consistent with an L4–L6 myelopathy. Ectopic calcification of so…
View article: Primary Feline Tauopathy: Clinical, Morphological, Immunohistochemical, and Genetic Studies
Primary Feline Tauopathy: Clinical, Morphological, Immunohistochemical, and Genetic Studies Open
Tauopathies are a group of neurodegenerative diseases characterized by the pathological aggregation of hyperphosphorylated tau in neurons and glia. Primary tauopathies are not uncommon in humans but exceptional in other species. We evaluat…
View article: Microanatomical findings with relevance to trigeminal ganglion enhancement on post-contrast T1-weighted magnetic resonance images in dogs
Microanatomical findings with relevance to trigeminal ganglion enhancement on post-contrast T1-weighted magnetic resonance images in dogs Open
Introduction Trigeminal ganglion contrast enhancement (TGCE) is reported to be a normal and a common finding on magnetic resonance imaging studies of dogs, cats and humans. The intent of the present study was to describe the anatomical cha…
View article: Standardization of canine meningioma grading: Validation of new guidelines for reproducible histopathologic criteria
Standardization of canine meningioma grading: Validation of new guidelines for reproducible histopathologic criteria Open
Canine meningiomas are currently graded using the human grading system. Recently published guidelines have adapted the human grading system for use in dogs. The goal of this study was to validate the new guidelines for canine meningiomas. …
View article: Immunohistochemical evaluation of fibrin/fibrinogen, d-dimers, and intravascular thrombosis in brains of dogs with meningoencephalitis of unknown origin
Immunohistochemical evaluation of fibrin/fibrinogen, d-dimers, and intravascular thrombosis in brains of dogs with meningoencephalitis of unknown origin Open
Granulomatous meningoencephalitis (GME) and necrotizing encephalitides (NE) are the most common immune-mediated inflammatory diseases of the central nervous system in dogs. Activation of the fibrinolytic system in multiple sclerosis, a sim…
View article: Editorial: Feline tumors of nervous system
Editorial: Feline tumors of nervous system Open
EDITORIAL article Front. Vet. Sci., 05 May 2023Sec. Veterinary Neurology and Neurosurgery Volume 10 - 2023 | https://doi.org/10.3389/fvets.2023.1200687
View article: Metastatic Multifocal Malignant Peripheral Nerve Sheath Tumour in the Cervicothoracic Spinal Cord of a Dog Initially Mimicking Meningomyelitis
Metastatic Multifocal Malignant Peripheral Nerve Sheath Tumour in the Cervicothoracic Spinal Cord of a Dog Initially Mimicking Meningomyelitis Open
A nine year old cross-breed dog was presented with a two week history of ambulatory tetraparesis and proprioceptive ataxia affecting all four limbs. Meningomyelitis of Unknown Origin (MUO) was presumptively diagnosed based on the magnetic …
View article: Intracranial Granular Cell Tumours in Three Dogs: Atypical Magnetic Resonance Imaging Features and Immunohistochemical Study
Intracranial Granular Cell Tumours in Three Dogs: Atypical Magnetic Resonance Imaging Features and Immunohistochemical Study Open
Intracranial granular cell tumours (GCT) are uncommon neoplasms of uncertain cellular origin that are rarely reported in dogs. This case series describes three aged dogs that presented with neurological signs in which magnetic resonance (M…
View article: Systemic cellular viroimmunotherapy for canine high-grade gliomas
Systemic cellular viroimmunotherapy for canine high-grade gliomas Open
Background Oncolytic viruses constitute a growing field of interest, both in human and veterinary oncology, given that they are particularly helpful for treating non-surgical tumors and disseminated cancer, such as high-grade gliomas. Comp…
View article: Spinocerebellar ataxia in the Bouvier des Ardennes breed is caused by a <scp>KCNJ10</scp> missense variant
Spinocerebellar ataxia in the Bouvier des Ardennes breed is caused by a <span>KCNJ10</span> missense variant Open
Background In Belgian Malinois, a KCNJ10 variant causes progressive spinocerebellar degeneration. Hypothesis/Objectives Describe the clinical, diagnostic, pathological and genetic features of spinocerebellar degeneration in the Bouvier des…
View article: Clinical and magnetic resonance imaging features, and pathological findings of spinal lymphoma in 27 cats
Clinical and magnetic resonance imaging features, and pathological findings of spinal lymphoma in 27 cats Open
This multicentric retrospective study describes the clinical and MRI features and pathological studies of spinal lymphoma in 27 cats. MRI characteristics and their possible correlations with histopathological findings were studied. The mos…
View article: First Case of a Cerebrocortical Ganglioglioma in a Dog
First Case of a Cerebrocortical Ganglioglioma in a Dog Open
Gangliogliomas are extremely rare tumors of the nervous system composed of neoplastic glial and neuronal cells. The aim of the present paper is to describe the clinical presentation, magnetic resonance imaging (MRI) findings and histopatho…
View article: Survival Time after Surgical Debulking and Temozolomide Adjuvant Chemotherapy in Canine Intracranial Gliomas
Survival Time after Surgical Debulking and Temozolomide Adjuvant Chemotherapy in Canine Intracranial Gliomas Open
Intracranial gliomas are associated with a poor prognosis, and the most appropriate treatment is yet to be defined. The objectives of this retrospective study are to report the time to progression and survival times of a group of dogs with…