Idriss Lahlou Amine
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View article: Circulating Tumor DNA as a Biomarker for Precision Medicine in Prostate Cancer: A Systematic Review
Circulating Tumor DNA as a Biomarker for Precision Medicine in Prostate Cancer: A Systematic Review Open
Circulating tumor DNA (ctDNA) profiling offers non-invasive insights for personalized prostate cancer management. This systematic review provides the first comprehensive appraisal of ctDNA assay methods, genomic targets, and their clinical…
View article: CYTOMEGALOVIRUS INFECTION IN ADULT IMMUNOCOMPROMISED PATIENTS: A 10-MONTH STUDY CONDUCTED AT MOHAMMED V MILITARY TEACHING HOSPITAL
CYTOMEGALOVIRUS INFECTION IN ADULT IMMUNOCOMPROMISED PATIENTS: A 10-MONTH STUDY CONDUCTED AT MOHAMMED V MILITARY TEACHING HOSPITAL Open
View article: HIV-1 Subtype Diversity in Morocco: Signals of Change and Implications for National Surveillance
HIV-1 Subtype Diversity in Morocco: Signals of Change and Implications for National Surveillance Open
Background: Limited molecular surveillance continues to constrain Morocco’s HIV response, leaving subtype dynamics largely underreported. Once characterized by a predominance of subtype B, the Moroccan epidemic now appears to reflect shift…
View article: Aplastic Anemia Induced by Parvovirus B19 Infection in an Immunocompetent Adult: A Case Report and Literature Review
Aplastic Anemia Induced by Parvovirus B19 Infection in an Immunocompetent Adult: A Case Report and Literature Review Open
A 24-year-old male presented with epistaxis and gingival bleeding, physical examination revealed pallor and purpuric spots on the left upper limb. Laboratory findings showed pancytopenia. As part of the etiological workup for pancytopenia,…
View article: Potency and Safety of <i>KRAS</i> G12C Inhibitors in Solid Tumors: A Systematic Review
Potency and Safety of <i>KRAS</i> G12C Inhibitors in Solid Tumors: A Systematic Review Open
Background: The Kirsten rat sarcoma viral oncogene homolog (KRAS) gene, specifically the cysteine residue mutation KRAS (G12C), has garnered significant attention as a therapeutic target for solid cancer patients with KRAS mutations. Despi…
View article: Association study of the JAK/STAT signaling pathway with susceptibility to COVID-19 in moroccan patient and in-silico analysis of rare variants
Association study of the JAK/STAT signaling pathway with susceptibility to COVID-19 in moroccan patient and in-silico analysis of rare variants Open
View article: Neutralising antibodies against SARS-CoV-2 give important information on Covid-19 epidemic evolution in Rabat, Morocco, March 2020-February 2021
Neutralising antibodies against SARS-CoV-2 give important information on Covid-19 epidemic evolution in Rabat, Morocco, March 2020-February 2021 Open
Background: The SARS-CoV-2 is an extremely contagious and acute viral disease mainly affecting humans.
Objective: To estimate seroprevalence of SARS-CoV-2 neutralizing antibodies (NAbs) for illegible armed force individuals living in Raba…
View article: Epidemiological and clinical aspects of chronic infections of hepatitis b virus at the Mohammed V military teaching hospital in Rabat – Morocco
Epidemiological and clinical aspects of chronic infections of hepatitis b virus at the Mohammed V military teaching hospital in Rabat – Morocco Open
Background: Infection with hepatitis B virus is a major public health problem worldwide. Globally hepatitis B virus’s prevalence is 5.4%, more than one million between them die each year from complications that are essenti…
View article: Epidemiological and clinical aspects of chronic infections of hepatitis b virus at the Mohammed V military teaching hospital in Rabat – Morocco
Epidemiological and clinical aspects of chronic infections of hepatitis b virus at the Mohammed V military teaching hospital in Rabat – Morocco Open
Background: Infection with hepatitis B virus is a major public health problem worldwide. Globally hepatitis B virus’s prevalence is 5.4%, more than one million between them die each year from complications that are essentially cirrhosis an…
View article: Genetic Susceptibility to Severe Forms of COVID-19: What we learned in 2022
Genetic Susceptibility to Severe Forms of COVID-19: What we learned in 2022 Open
Host genetics of COVID-19 patients is constantly evolving and may play an important role in the management of hospitalized patients and the identification of new biomarkers. In 2022, numerous studies have been published examining genetic f…
View article: Prevalence and Patterns of EGFR Mutations in Non-small Cell Lung Cancer in the Middle East and North Africa
Prevalence and Patterns of EGFR Mutations in Non-small Cell Lung Cancer in the Middle East and North Africa Open
Objectives This study aims to analyze the prevalence and spectrum of epidermal growth factor receptor (EGFR) mutations within the Middle East and North Africa region, compare the findings to other parts of the world, and explore the geogra…
View article: Prevalence and Patterns of EGFR Mutations in Non-Small Cell Lung Cancer in the Middle East and North Africa: A Systematic Review
Prevalence and Patterns of EGFR Mutations in Non-Small Cell Lung Cancer in the Middle East and North Africa: A Systematic Review Open
To summarize current evidence and estimate the prevalence of epidermal growth factor receptor ( EGFR ) mutation frequency and its association with ethnicity and clinic-pathological features in non-small cell lung cancer (NSCLC) patients in…
View article: Epidemiological, Clinical and Virological Characteristics of Patients with Hepatitis C in Morocco
Epidemiological, Clinical and Virological Characteristics of Patients with Hepatitis C in Morocco Open
Objectives: In Morocco, the exact and recent prevalence of Hepatitis C Virus (HCV) infection is not well-known, due to the lack of recent epidemiological studies of the general Moroccan population. The objective of this study was to determ…
View article: Role of Training and Experience in Biosafety Practices Among Nurses Working in Level 2 or 3 Patient Containment
Role of Training and Experience in Biosafety Practices Among Nurses Working in Level 2 or 3 Patient Containment Open
Safety training should begin early in the training curriculum with theoretical and practical courses. It must be introduced into the general biosafety policy as part of a safety and standard working culture. It is recommended that personne…
View article: Fatal Respiratory Syncytial Virus Infection in Immunocompetent Adult: A Case Report
Fatal Respiratory Syncytial Virus Infection in Immunocompetent Adult: A Case Report Open
Background: Respiratory syncytial virus (RSV) is the most common pathogen that causes acute lower respiratory tract infection in infants and young children. However, very rarely, RSV can induce acute respiratory distress syndr…
View article: Middle East respiratory syndrome in Morocco: four years of surveillance and evaluation of the management of suspected cases
Middle East respiratory syndrome in Morocco: four years of surveillance and evaluation of the management of suspected cases Open
Background: In early 2014, Morocco took steps to prevent the Middle East respiratory syndrome disease from entering into the country. Several facilities have been equipped to accommodate suspected cases. We aimed to report the plan prepare…
View article: Knowledge of Biosafety Among Workers in Private and Public Clinical and Research Laboratories in Morocco
Knowledge of Biosafety Among Workers in Private and Public Clinical and Research Laboratories in Morocco Open
These findings underline the need for establishing a biosafety policy and strengthening biosafety training programs in laboratories in Morocco.
View article: Dengue fever in Morocco: result of surveillance during the year 2017 and first imported cases
Dengue fever in Morocco: result of surveillance during the year 2017 and first imported cases Open
Dengue is a significant mosquito-borne infection in humans, and its worldwide prevalence is rapidly increasing. The vector aedes albopictus has been revealed recently in the town of Rabat. Morocco established a program of active surveillan…
View article: Consumption of antibacterial molecules in broiler production in Morocco
Consumption of antibacterial molecules in broiler production in Morocco Open
Monitoring the use of antibacterial agents in food‐producing animals is crucial in order to reduce antimicrobial resistance, selection and dissemination of resistant bacterial strains, and drug residues in the animal food products. The bro…
View article: Chikungunya infection confirmed in a Moroccan traveller returning from Bangladesh
Chikungunya infection confirmed in a Moroccan traveller returning from Bangladesh Open
Recently, several countries reported imported cases of infection with chikungunya virus (CHIKV). We report the first case of chikungunya virus infection in Morocco. A 37-year old woman returned to Morocco on 15 August 2017, after she staye…
View article: Détection de souches multi-résistantes d’Escherichia coli d’origine aviaire dans la région de Rabat-Salé-Zemmour-Zaer
Détection de souches multi-résistantes d’Escherichia coli d’origine aviaire dans la région de Rabat-Salé-Zemmour-Zaer Open
\nLa surveillance de l’antibio-résistance de germes spécifiques comme E. coli, Salmonella spp., Staph. aureus ou Campylobacter requiert une importance particulière dans la politique sanitaire humaine et vétérinaire des pays. Dans cette opt…
View article: Impact of neuraminidase inhibitors on influenza A(H1N1)pdm09‐related pneumonia: an individual participant data meta‐analysis
Impact of neuraminidase inhibitors on influenza A(H1N1)pdm09‐related pneumonia: an individual participant data meta‐analysis Open
Background The impact of neuraminidase inhibitors ( NAI s) on influenza‐related pneumonia ( IRP ) is not established. Our objective was to investigate the association between NAI treatment and IRP incidence and outcomes in patients hospita…