Explanipedia

Onchocerciasis-associated skin and ocular disease and the impact of ivermectin treatment on morbidity prevalence: a modelling study Open

Matthew A. Dixon, Aditya Ramani, Martin Walker, Jacob N. Stapley, Michele E. Murdoch , et al. · 2025

Background Despite decades of control interventions in sub-Saharan Africa, morbidity associated with Onchocerca volvulus infection still exerts a substantial burden of disease, arising from cutaneous, ocular and neurological manifestations…

Selective Laser Trabeculoplasty in Northern Ghana Open

Jean–Claude Simon, Thomas Kenny, Ian Murdoch · 2024

We present an audit in Northern Ghana. A total of 283 selective laser trabeculoplasties (SLTs) were done between September 2021 and September 2024. Because of collinearity between right and left eye response to therapy, 145 eyes in 145 ind…

West African College of Surgeons Basic Ophthalmology Resource: Development and Initial Evaluation Open

Shuaib Abdulsalam, Dupe Popoola, Adetunje Adenekan, OlukoredeO Adenuga, Adedayo Adio , et al. · 2024

Purpose: To describe the process of development of the West African College of Surgeons (WACS) Basic Ophthalmology Educational Resource and to report the feedback from the first five cohorts to utilise the resource at the commencement of t…

Proportion of angle closure glaucoma in Tamale, Ghana Open

Catherine Liu, Omair Ali, Ian Murdoch, Judith C. Simon · 2023

Background/Objectives: Glaucoma is the second leading cause of blindness worldwide. In Africa, glaucoma is an established public health problem, and primary angle-closure glaucoma (PACG) is not commonly discussed. Recognizing it is importa…

Visual function rather than visual acuity Open

Ian Murdoch, David P. Crabb · 2021

Glaucoma and glare Open

Mehran Hamedani, Barbara Dulley, Ian Murdoch · 2020

The cost and quality of life impact of glaucoma in Tanzania: An observational study Open

Ian Murdoch, Andrew F. Smith, Helen Baker, Bernadetha Shilio, Kazim Dhalla · 2020

These findings are of great importance for health care planners seeking to determine cost-effective, acceptable methods of both identifying and treating this major cause of preventable blindness.

Initial experience in self-monitoring of intraocular pressure Open

Emily McGarva, Jane Farr, Priya Dabasia, John G Lawrenson, Ian Murdoch · 2020

Background/aims Diurnal variation in intraocular pressure (IOP) is a routine assessment in glaucoma management. Providing patients the opportunity to perform self-tonometry might empower them and free hospital resource. We previously demon…

Steroid Response and Vexol Open

Ian Murdoch, Bina Parmar, Ian Murdoch · 2020

Raised intraocular pressure from topical steroid application is well recognised. Frequently prednisolone, dexamethasone or betamethasone are replaced with Vexol. We report a case of steroid responsiveness to Vexol of note since it was conf…

Adherence with Medical Therapy for Primary Open-Angle Glaucoma in Kenya – A Pilot Study Open

Ian Murdoch, David Nyakundi, H Baker, Simon Dulku, Dan Kiage · 2020

Ian Murdoch, 1 David Nyakundi, 2 Helen Baker, 1 Simon Dulku, 3 Daniel Kiage 2 1Institute of Ophthalmology, London EC1V 9EL, UK; 2Innovation Eye Centre Ltd, Kisii, Kenya; 3University Hospitals Birmingham NHS Foundation Trust, Birmingham B15…

Adherence with Medical Therapy for Primary Open-Angle Glaucoma in Kenya – A Pilot Study Open

Ian Murdoch, David Nyakundi, Helen Baker, Simon Dulku, Daniel Kiage · 2020

The signs of poor adherence based on both self-report (previous literature), and in this small-scale study of an objective measure suggest medication may not be the first-line treatment of choice in this environment. Our report does, howev…

Small core FBG-based temperature compensated ‘smart’ contact lens for effective intraocular pressure measurement Open

Ye Chen, Jun Wang, Yin Zhao, Xiaojun Liu, Hong Zhang , et al. · 2019

In this work, a small core, Fibre Bragg Grating (FBG)-based smart contact lens for intraocular pressure (IOP) measurement has been demonstrated. Further, an integral temperature compensation mechanism has been developed and included in the…

Perceptions of training in gonioscopy Open

Rui Feng, Sheila Luk, Clara Hoi Ka Wu, Laura Crawley, Ian Murdoch · 2019

Response to: Comment on ‘How do paper and electronic records compare for completeness? A three centre study’ Open

Clara Hoi Ka Wu, Sheila Luk, Richard L. Holder, Zena Rodrigues, Faisal Ahmed , et al. · 2019

Long-term follow-up of phacotrabeculectomy surgery in Tanzania Open

Ian Murdoch, Helen Baker, Capucine Odouard, Imani Kapessa, Jonathan Clarke , et al. · 2019

Correction: How do paper and electronic records compare for completeness? A three centre study Open

Clara Hoi Ka Wu, Sheila Luk, Richard L. Holder, Zena Rodrigues, Faisal Ahmed , et al. · 2019

How do paper and electronic records compare for completeness? A three centre study Open

Clara Hoi Ka Wu, Sheila Luk, Richard L. Holder, Zena Rodrigues, Faisal Ahmed , et al. · 2018

Reproducibility of the OQUAL grid cataract grading system in an African setting. Open

Sandeep Bhatt, F Bekele, Ian Murdoch · 2018

Aim: There is no universal grading system for age-related cataracts. ‘Lens Opacities Classification System III’ (LOCS III), the current gold standard, requires lengthy training, is not time or costeffective and can have poor patient cooper…

Same-site surgical revision of failed trabeculectomy blebs with mitomycin C augmentation: long-term follow-up Open

Eleni Nikita, Ian Murdoch · 2017

Pre-control relationship of onchocercal skin disease with onchocercal infection in Guinea Savanna, Northern Nigeria Open

Michele E. Murdoch, Ian Murdoch, Jennifer Evans, H Yahaya, N Njepuome , et al. · 2017

Significant levels of onchocercal skin disease were documented in this savanna area, which subsequently resulted in a reassessment of the true burden of skin disease in onchocerciasis. This paper represents the first detailed report of the…

Is Beta Radiation Better than 5 Flurouracil as an Adjunct for Trabeculectomy Surgery When Combined with Cataract Surgery? A Randomised Controlled Trial Open

Kazim Dhalla, Simon Cousens, Richard Bowman, Mark Wood, Ian Murdoch · 2016

ISRCTN Registry ISRCTN36436933.

Results and safety profile of trainee cataract surgeons in a community setting in East Africa Open

Nikolaos Mavrakanas, Kazim Dhalla, Jerry Jecha, Imani Kapesa, Capucine Odouard , et al. · 2016

AMO-O cataract surgeons at the end of their training offer significant improvement in the visual acuity of their patients. Continuous monitoring of outcomes will guide further improvements in surgical skills and minimize complications.

Noncontact Screening Methods for the Detection of Narrow Anterior Chamber Angles Open

Priya Dabasia, David F. Edgar, Ian Murdoch, John G Lawrenson · 2015

Van Herick test and Visante OCT ACA exhibited best discrimination between narrow and open angles both alone, and in combination. Van Herick test affords advantages over Visante OCT, showing potential for identifying individuals who may ben…

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