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View article: <scp>CDK8</scp> /19 inhibition triggers a switch from mitosis to endomitosis in cord blood megakaryocytes
<span>CDK8</span> /19 inhibition triggers a switch from mitosis to endomitosis in cord blood megakaryocytes Open
Summary Neonatal and adult megakaryocytes differ in proliferative capacity and ploidy levels, and neonatal and adult platelets differ in function, gene expression, and protein content. The mechanisms underlying these differences are incomp…
View article: Incorporation of a nucleoside analog maps genome repair sites in postmitotic human neurons
Incorporation of a nucleoside analog maps genome repair sites in postmitotic human neurons Open
DNA repair within neurons Humans have only a limited capacity to generate new neurons. These cells thus need to repair errors in the genome. To better understand this process, Reid et al. developed Repair-seq, a method to locate DNA repair…