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View article: Updated 2025 French guidelines for renal cell carcinoma
Updated 2025 French guidelines for renal cell carcinoma Open
The 2025 update of the French guidelines for localized renal cell carcinoma highlights several major advances. Renal biopsy reaffirms its central role in guiding therapeutic decisions and reducing overtreatment, with growing evidence suppo…
View article: Racial differences in kidney cancer histology and outcome: A nationwide study from the UroCCR Cohort
Racial differences in kidney cancer histology and outcome: A nationwide study from the UroCCR Cohort Open
Black patients in France exhibit a higher prevalence of non–clear cell renal cell carcinoma subtypes and are diagnosed at younger ages with earlier‐stage tumors. These patterns, along with distinct transcriptomic profiles in nonneoplastic …
View article: Role of radiotherapy in the management of primary renal cell carcinoma: Recommendations from the Société française de radiothérapie oncologique (SFRO, the French society for radiation oncology)
Role of radiotherapy in the management of primary renal cell carcinoma: Recommendations from the Société française de radiothérapie oncologique (SFRO, the French society for radiation oncology) Open
Renal cell carcinoma represents the 14th most frequent tumour worldwide, but its incidence is increasing partly due to incidental diagnoses. As a result, these tumours are diagnosed in patients at an increasingly advanced age, often frail …
View article: Arterial Embolization versus Robotic Partial Nephrectomy for the Treatment of Renal Angiomyolipomas
Arterial Embolization versus Robotic Partial Nephrectomy for the Treatment of Renal Angiomyolipomas Open
Objective: To compare the outcomes of robotic-assisted partial nephrectomy (RALPN) and selective arterial embolization (SAE) for the treatment of sporadic renal angiomyolipoma (AML). Patients and methods: The outcomes of patients who were …
View article: New chemotherapy delivery devices in bladder cancer management
New chemotherapy delivery devices in bladder cancer management Open
View article: High prevalence and negative impact of sarcopenia on oncological outcomes in patients with upper tract urothelial carcinoma treated with radical nephroureterectomy
High prevalence and negative impact of sarcopenia on oncological outcomes in patients with upper tract urothelial carcinoma treated with radical nephroureterectomy Open
View article: Emerging evidence of immunotherapy in BCG-unresponsive non-muscle invasive bladder cancer
Emerging evidence of immunotherapy in BCG-unresponsive non-muscle invasive bladder cancer Open
View article: Muscle-invasive bladder cancer: role of adjuvant immunotherapy
Muscle-invasive bladder cancer: role of adjuvant immunotherapy Open
View article: Active surveillance for non-muscle-invasive bladder cancer: a systematic review
Active surveillance for non-muscle-invasive bladder cancer: a systematic review Open
View article: High-dose intravesical epirubicin for BCG-unresponsive high-risk non-muscle-invasive bladder cancer
High-dose intravesical epirubicin for BCG-unresponsive high-risk non-muscle-invasive bladder cancer Open
View article: Initial Management and Reconstructive Surgery Algorithm for Fournier Gangrene
Initial Management and Reconstructive Surgery Algorithm for Fournier Gangrene Open
Multidisciplinary step-by-step management of Fournier gangrene including our reconstruction approach based on lesion extension can be achieved with minimal mortality and with good results for the patients.
View article: Racial Disparities in Renal Cell Carcinoma Histology and Outcomes: Insights from the French Kidney Cancer Research Network (UroCCR-191)
Racial Disparities in Renal Cell Carcinoma Histology and Outcomes: Insights from the French Kidney Cancer Research Network (UroCCR-191) Open
View article: French AFU Cancer Committee Guidelines – Update 2024–2026: Management of kidney cancer
French AFU Cancer Committee Guidelines – Update 2024–2026: Management of kidney cancer Open
These updated recommendations are a reference that will enable French and French-speaking practitioners to optimize their management of kidney cancer.
View article: Measuring and correcting staff variability in large-scale OSCEs
Measuring and correcting staff variability in large-scale OSCEs Open
Staff variability impacts OSCE scores as much as student variability, and the former can be reduced with dual assessment or adjusted for with mixed models. Both are small compared to unmeasured sources of variability, making them difficult…
View article: The Impact of Histological Variants on Oncological Outcomes After Surgical Resection of a Nonmetastatic Renal Cell Carcinoma with Tumor Thrombus: A Multi-institutional Study
The Impact of Histological Variants on Oncological Outcomes After Surgical Resection of a Nonmetastatic Renal Cell Carcinoma with Tumor Thrombus: A Multi-institutional Study Open
View article: Primary bladder neck obstruction in men: The importance of urodynamic assessment and cystourethrography in measuring its severity
Primary bladder neck obstruction in men: The importance of urodynamic assessment and cystourethrography in measuring its severity Open
Objective Primary bladder neck obstruction (PBNO) is a condition primarily affecting young men, characterized by obstruction at the bladder neck, leading to lower urinary tract symptoms. The aim of this study was to identify a correlation …
View article: Large-scale analysis of cell-cell communication reveals angiogenin-dependent tumor progression in clear cell renal cell carcinoma
Large-scale analysis of cell-cell communication reveals angiogenin-dependent tumor progression in clear cell renal cell carcinoma Open
Cellular crosstalk in the tumor microenvironment (TME) is still largely uncharacterized, while it plays an essential role in shaping immunosuppression or anti-tumor response. Large-scale analyses are needed to better decipher cell-cell com…
View article: Factors predicting the active treatment of renal angiomyolipoma: 30 years of experience in two tertiary referral centers
Factors predicting the active treatment of renal angiomyolipoma: 30 years of experience in two tertiary referral centers Open
Introduction and objective This study aimed to identify clinical features representing predictive factors of active treatment (AT) compared to active surveillance (AS) for renal angiomyolipoma (AML). Patients and methods From 1990 to 2020,…
View article: Data from <i>Escherichia coli</i>–Specific CXCL13-Producing T<sub>FH</sub> Are Associated with Clinical Efficacy of Neoadjuvant PD-1 Blockade against Muscle-Invasive Bladder Cancer
Data from <i>Escherichia coli</i>–Specific CXCL13-Producing T<sub>FH</sub> Are Associated with Clinical Efficacy of Neoadjuvant PD-1 Blockade against Muscle-Invasive Bladder Cancer Open
Biomarkers guiding the neoadjuvant use of immune-checkpoint blockers (ICB) are needed for patients with localized muscle-invasive bladder cancers (MIBC). Profiling tumor and blood samples, we found that follicular helper CD4+ T …
View article: Supplementary Figure from <i>Escherichia coli</i>–Specific CXCL13-Producing T<sub>FH</sub> Are Associated with Clinical Efficacy of Neoadjuvant PD-1 Blockade against Muscle-Invasive Bladder Cancer
Supplementary Figure from <i>Escherichia coli</i>–Specific CXCL13-Producing T<sub>FH</sub> Are Associated with Clinical Efficacy of Neoadjuvant PD-1 Blockade against Muscle-Invasive Bladder Cancer Open
Supplementary Figure from Escherichia coli–Specific CXCL13-Producing TFH Are Associated with Clinical Efficacy of Neoadjuvant PD-1 Blockade against Muscle-Invasive Bladder Cancer
View article: Supplementary Figure from <i>Escherichia coli</i>–Specific CXCL13-Producing T<sub>FH</sub> Are Associated with Clinical Efficacy of Neoadjuvant PD-1 Blockade against Muscle-Invasive Bladder Cancer
Supplementary Figure from <i>Escherichia coli</i>–Specific CXCL13-Producing T<sub>FH</sub> Are Associated with Clinical Efficacy of Neoadjuvant PD-1 Blockade against Muscle-Invasive Bladder Cancer Open
Supplementary Figure from Escherichia coli–Specific CXCL13-Producing TFH Are Associated with Clinical Efficacy of Neoadjuvant PD-1 Blockade against Muscle-Invasive Bladder Cancer
View article: Data from <i>Escherichia coli</i>–Specific CXCL13-Producing T<sub>FH</sub> Are Associated with Clinical Efficacy of Neoadjuvant PD-1 Blockade against Muscle-Invasive Bladder Cancer
Data from <i>Escherichia coli</i>–Specific CXCL13-Producing T<sub>FH</sub> Are Associated with Clinical Efficacy of Neoadjuvant PD-1 Blockade against Muscle-Invasive Bladder Cancer Open
Biomarkers guiding the neoadjuvant use of immune-checkpoint blockers (ICB) are needed for patients with localized muscle-invasive bladder cancers (MIBC). Profiling tumor and blood samples, we found that follicular helper CD4+ T …
View article: Can Molecular Classifications Help Tailor First-line Treatment of Metastatic Renal Cell Carcinoma? A Systematic Review of Available Models
Can Molecular Classifications Help Tailor First-line Treatment of Metastatic Renal Cell Carcinoma? A Systematic Review of Available Models Open
First-line treatment of metastatic kidney includes immunotherapy alone or in combination with antiangiogenic therapy. However, clinical practice demonstrated that the "one treatment fits all" strategy might not be the best approach. In fac…
View article: Effect of bladder filling volume on detrusor contractility in men with bladder outlet obstruction
Effect of bladder filling volume on detrusor contractility in men with bladder outlet obstruction Open
Introduction Bladder outlet obstruction alters detrusor contractility, reducing the bladder ' s ability to respond to large filling with a risk of urinary retention. The objective was to assess the effect of bladder filling volume on detru…
View article: <i>Escherichia coli</i> –Specific CXCL13-Producing TFH Are Associated with Clinical Efficacy of Neoadjuvant PD-1 Blockade against Muscle-Invasive Bladder Cancer
<i>Escherichia coli</i> –Specific CXCL13-Producing TFH Are Associated with Clinical Efficacy of Neoadjuvant PD-1 Blockade against Muscle-Invasive Bladder Cancer Open
Biomarkers guiding the neoadjuvant use of immune-checkpoint blockers (ICB) are needed for patients with localized muscle-invasive bladder cancers (MIBC). Profiling tumor and blood samples, we found that follicular helper CD4+ T cells (TFH)…
View article: Table of Contents
Table of Contents Open
View article: Lymph Node Dissection During Radical Nephro-Ureterectomy for Upper Tract Urothelial Carcinoma: A Review
Lymph Node Dissection During Radical Nephro-Ureterectomy for Upper Tract Urothelial Carcinoma: A Review Open
Although lymphonodal dissection is well-accepted for muscle-invasive bladder cancer management, its role is still debated during radical nephroureterectomy (RNU) for upper tract urothelial carcinoma (UTUC). The aim of this study was to sum…
View article: Current Advances in Immune Checkpoint Inhibition and Clinical Genomics in Upper Tract Urothelial Carcinoma: State of the Art
Current Advances in Immune Checkpoint Inhibition and Clinical Genomics in Upper Tract Urothelial Carcinoma: State of the Art Open
Upper tract urothelial carcinoma (UTUC) is a rare and challenging-to-treat malignancy. In most patients it is a sporadic tumor entity, less commonly it falls on the spectrum of Lynch syndrome, an autosomal dominant familial tumor syndrome.…
View article: External Validation of the ASSURE Model for Predicting Oncological Outcomes After Resection of High-risk Renal Cell Carcinoma (RESCUE Study: UroCCR 88)
External Validation of the ASSURE Model for Predicting Oncological Outcomes After Resection of High-risk Renal Cell Carcinoma (RESCUE Study: UroCCR 88) Open
View article: Cardiovascular Safety of Degarelix Versus Leuprolide in Patients With Prostate Cancer: The Primary Results of the PRONOUNCE Randomized Trial
Cardiovascular Safety of Degarelix Versus Leuprolide in Patients With Prostate Cancer: The Primary Results of the PRONOUNCE Randomized Trial Open
Background: The relative cardiovascular safety of gonadotropin-releasing hormone (GnRH) antagonists compared with GnRH agonists in men with prostate cancer and known atherosclerotic cardiovascular disease remains controversial. Methods: In…