А. I. Poptsov
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View article: 3-Pyridinylidene Derivatives of Chemically Modified Lupane and Ursane Triterpenes as Promising Anticancer Agents by Targeting Apoptosis
3-Pyridinylidene Derivatives of Chemically Modified Lupane and Ursane Triterpenes as Promising Anticancer Agents by Targeting Apoptosis Open
Cancer persists as a global challenge due to the extent to which conventional anticancer therapies pose high risks counterbalanced with their therapeutic benefit. Naturally occurring substances stand as an important safer alternative sourc…
View article: Synthesis and alpha ‐ inhibitory activity of lupane type <scp>С2</scp>‐benzylidene‐ triterpenoids
Synthesis and alpha ‐ inhibitory activity of lupane type <span>С2</span>‐benzylidene‐ triterpenoids Open
A series of novel and previously synthesized lupane type С2‐benzylidene derivatives was evaluated on α ‐glucosidase enzyme inhibition. Most of the tested compounds exhibited significantly better activity (1.8‐700 times higher) than the sta…
View article: Synthesis and Cytotoxic Potential of 3-Oxo-19β-trifluoroacetoxy-18αH-oleane-28-oic Acid
Synthesis and Cytotoxic Potential of 3-Oxo-19β-trifluoroacetoxy-18αH-oleane-28-oic Acid Open
Trifluoroacetic acid-promoted Wagner-Meerwein rearrangement of betulonic acid carboxamide led to the formation of the expected 19β,28-lactam along with a new germanicane-type 3-oxo-19β-trifluoroacetoxy-18αH-oleane-28-oic acid. The structur…
View article: CCDC 974813: Experimental Crystal Structure Determination
CCDC 974813: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …