Roberto Martı́nez
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Eta Fragmentation Functions Revisited Open
We revisit the extraction of parton-to-eta meson fragmentation functions at next-to-leading order accuracy in QCD in the light of the recent hadroproduction measurements in proton-proton collisions obtained by the PHENIX, LHCb, and ALICE c…
¡Humo! ¡Alerta! La amenaza invisible de las quemas agrícolas Open
In the context of the interaction between natural systems and human activities, seasonal agricultural burning represents a phenomenon with significant impacts on public health and the environment. In addition to the immediate risk associat…
Rational design of indolyl acrylamides as antibacterial agents targeting multidrug-resistant <i>Acinetobacter baumannii</i> strains Open
Antimicrobial resistance (AMR) has become a significant public health problem.
Pion Nuclear Fragmentation Functions Revisited Open
We revisit the notion of nuclear parton-to-pion fragmentation functions at next-to-leading order accuracy as an effective description of hadroproduction in nuclear environments such as in semi-inclusive lepton-nucleus deep-inelastic scatte…
(2Z)-3-Hydroxy-3-(4-R-Phenyl)-Prop-2-Enedithioic Acids as New Antituberculosis Compounds Open
Our results suggested that the antituberculosis compound 11e could be used for the design of novel antituberculosis agents.
Nucleus-Independent Chemical Shift (NICS) as a Criterion for the Design of New Antifungal Benzofuranones Open
The assertion made by Wu et al. that aromaticity may have considerable implications for molecular design motivated us to use nucleus-independent chemical shifts (NICS) as an aromaticity criterion to evaluate the antifungal activity of two …
Synthesis of novel pyrroloazepinones by Schmidt expansions of 6-indolones Open
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An Amphiphilic Polymer-Supported Strategy Enables Chemical Transformations under Anhydrous Conditions for DNA-Encoded Library Synthesis Open
The use of DNA-encoded libraries has emerged as a powerful hit generation technology. Combining the power of combinatorial chemistry to enumerate large compound collections with the efficiency of affinity selection in pools, the methodolog…
An Amphiphilic Polymer-Supported Strategy Enables Chemical Transformations Under Anhydrous Conditions for DNA-Encoded Library Synthesis Open
Herein, we describe the development of a practical catch-and release methodology utilizing a cationic, amphiphilic PEG-based polymer to perform chemical transformations on immobilized DNA conjugates under anhydrous conditions. We demonstra…
Synthesis and antitubercular activity of new <i>N</i> -[5-(4-chlorophenyl)-1,3,4-oxadiazol-2-yl]-(nitroheteroaryl)carboxamides Open
Nitro-substituted heteroaromatic carboxamides 1a-e were synthesized and tested against three Mycobacterium tuberculosis cell lines. The activities can be explained in terms of the distribution of the electronic density across the nitro-sub…
Tryptophan-Containing Dual Neuroprotective Peptides: Prolyl Endopeptidase Inhibition and Caenorhabditis elegans Protection from β-Amyloid Peptide Toxicity Open
Neuroprotective peptides represent an attractive pharmacological strategy for the prevention or treatment of age-related diseases, for which there are currently few effective therapies. Lactoferrin (LF)-derived peptides (PKHs) and a set of…
5,6-Dihydropyrrolo[2,1-<i>a</i>]isoquinolines as Alternative of New Drugs with Cytotoxic Activity Open
In this study, the pyrrolo[2,1-a]isoquinolines 4a-n were synthesized in good yields in a three steps synthesis from the corresponding α,β-unsaturated esters starting materials. These compounds were tested on six human cancer cells lines to…
Pharmacological evaluation of 2-angeloyl<i>ent</i>-dihydrotucumanoic acid Open
The results indicate that ADTA, obtained from G. glutinosum, exerts moderate in vitro anti-inflammatory and in vivo antinociceptive effects, but lacks cytotoxic effects on human cancer cells.