Isah Abubakar Aliyu
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View article: Angiotensin converting enzyme gene polymorphism in Nigerians with peripartum cardiomyopathy
Angiotensin converting enzyme gene polymorphism in Nigerians with peripartum cardiomyopathy Open
The prevalence of ACE gene I/D polymorphism was not significantly different between PPCM patients and controls. ACE gene I/D polymorphism was not associated with PPCM in Kano, Nigeria.
View article: Seroprevalence of cytomegalovirus among pregnant women attending Murtala Muhammad Specialist Hospital, Kano
Seroprevalence of cytomegalovirus among pregnant women attending Murtala Muhammad Specialist Hospital, Kano Open
Cytomegalovirus (CMV) infection is a common cause of miscarriage, growth retardation and congenital infections in pregnancy. This congenital infection can cause serious disease to the foetus such as blindness and deafness. This study deter…
View article: MolecularDetection of Schistosoma haematobium DRA1 DNAin Urine and Serum Samples
MolecularDetection of Schistosoma haematobium DRA1 DNAin Urine and Serum Samples Open
No Abstract
View article: Assessing the Risk of Exposure to Vectors of Malaria using Entomological Inoculation Rate among Houses at Auyo Irrigation Rice Farming Community in Jigawa State
Assessing the Risk of Exposure to Vectors of Malaria using Entomological Inoculation Rate among Houses at Auyo Irrigation Rice Farming Community in Jigawa State Open
A longitudinal entomological survey of malaria vectors was carried out aiming to assess the transmission risk factors with regard to housing types at the rice irrigation community of Auyo LGA. The study was carried out in 32 households fro…
View article: Haematological profile in COVID-19: Insights from Kano, Nigeria
Haematological profile in COVID-19: Insights from Kano, Nigeria Open
Coronavirus Disease 2019 (COVID-19) was first diagnosed in Wuhan, China, in December 2019, and later declared a pandemic with a novel β-Coronavirus, Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) as the causative agent. Howev…
View article: A Pilot Study for Drug-Resistant Tuberculosis Disease Patients Suggests that A964G (rs153109)—Interleukin 27 may be Protective
A Pilot Study for Drug-Resistant Tuberculosis Disease Patients Suggests that A964G (rs153109)—Interleukin 27 may be Protective Open
Context: Variation in the transcription of host genes of inflammatory cytokines may underscore variation in their production. Thus, the host-immune status plays a vital role in determining the fate of the invading bacilli. Materials and Me…
View article: Role of the IL8 rs4073 polymorphism in central nervous system toxicity in patients receiving multidrug-resistant tuberculosis treatment
Role of the IL8 rs4073 polymorphism in central nervous system toxicity in patients receiving multidrug-resistant tuberculosis treatment Open
Objective: To determine the role of the IL8 rs4073 polymorphism in predicting the risk of central nervous system (CNS) toxicity in patients receiving standard pharmacological treatment for multidrug-resistant tuberculosis (MDR-TB). Methods…
View article: Prevalence of pulmonary histoplasmosis infection among Human Immunodeficiency Virus/Tuberculosis patients attending infectious diseases hospital, Kano, northwestern Nigeria
Prevalence of pulmonary histoplasmosis infection among Human Immunodeficiency Virus/Tuberculosis patients attending infectious diseases hospital, Kano, northwestern Nigeria Open
Histoplasmosis is a disease with a global distribution and hyperendemic zones. The severity of the sickness is determined by the number of conidia inhaled and the host’s cellular immune system’s performance. This study aimed to determine t…
View article: Identification of Potential Binding Region of Annexin II and Dengue Virus Envelop Glycoprotein
Identification of Potential Binding Region of Annexin II and Dengue Virus Envelop Glycoprotein Open
The tissue tropism of a virus is a key determinant of viral pathogenicity which is often modulated by the presence or absence of appropriate molecules on the surface of a host cell that can be used by the virus to gain entry into that cell…
View article: Identification of Potential Binding Region of Annexin II and Dengue Virus Envelop Glycoprotein
Identification of Potential Binding Region of Annexin II and Dengue Virus Envelop Glycoprotein Open
The tissue tropism of a virus is a key determinant of viral pathogenicity which is often modulated by the presence or absence of appropriate molecules on the surface of a host cell that can be used by the virus to gain entry into that cell…
View article: Significance of Pseudomonas aeruginosa efflux pump system in antibiotic resistance
Significance of Pseudomonas aeruginosa efflux pump system in antibiotic resistance Open
Pseudomonas aeruginosa (P. aeruginosa) is an opportunistic pathogen with a high morbidity andmortality rate in immunocompromised and cystic fibrosis patients. The treatment of P. aeruginosa infections is becoming increasingly difficult due…
View article: Pathobiological bases of asthma-COVID-19 interaction: A theoretical viewpoint
Pathobiological bases of asthma-COVID-19 interaction: A theoretical viewpoint Open
Patients with asthma are susceptible to viral respiratory infections, due to weakened cellular immunity, chronic airway inflammation, and some other reasons. In fact, asthma was found to be a comorbidity to the Middle East respiratory synd…
View article: Systematic Review on the Antibacterial Resistance of Vibrio Cholerae
Systematic Review on the Antibacterial Resistance of Vibrio Cholerae Open
Background: Vibrio cholerae is the causative agent of cholera illness. Antibacterial resistance of V. cholerae is frequently experienced due to the environmental pressure from human and animal overuse and misuse of antibacterials. Among su…
View article: Pattern Of Some Inflammatory Mediators Among Adult Patients With Bronchial Asthma On Corticosteroids Attending Aminu Kano Teaching Hospital, Kano, Nigeria
Pattern Of Some Inflammatory Mediators Among Adult Patients With Bronchial Asthma On Corticosteroids Attending Aminu Kano Teaching Hospital, Kano, Nigeria Open
Background Bronchial asthma in adults is typified by lingering allergic inflammation associated with elevation in the levels of certain acute phase reactants and indicators of mast cell activation. This study investigated the effect of cor…
View article: Identification of HPV16’s E6 gene in suspected cases of cervical lesions and docking study of its L1 protein with active components of Echinacea purpurae
Identification of HPV16’s E6 gene in suspected cases of cervical lesions and docking study of its L1 protein with active components of Echinacea purpurae Open
Background: HPV 16 is the primary etiologic agent of cervical cancer and the presence of L1 and E6 oncoproteins are largely responsible for its virulence. It was the objective of this study to identify HPV16 isolates from suspected cases o…
View article: Rapid, Cheap, and Effective COVID-19 Diagnostics for Africa
Rapid, Cheap, and Effective COVID-19 Diagnostics for Africa Open
Background: Although comprehensive public health measures such as mass quarantine have been taken internationally, this has generally been ineffective, leading to a high infection and mortality rate. Despite the fact that the COVID-19 pand…
View article: Proteomes, kinases and signalling pathways in virus‐induced filopodia, as potential antiviral therapeutics targets
Proteomes, kinases and signalling pathways in virus‐induced filopodia, as potential antiviral therapeutics targets Open
Summary Filopodia are thin finger‐like protrusions at the surface of cells that are internally occupied with bundles of tightly parallel actin filaments. They play significant roles in cellular physiological processes, such as adhesion to …
View article: Phytotherapy as an alternative for the treatment of human papilloma virus infections in Nigeria: a review
Phytotherapy as an alternative for the treatment of human papilloma virus infections in Nigeria: a review Open
Human papillomavirus (HPV) has been incriminated as the causal agent of cervical cancer which has been rated as the second most common cancers among women in developing countries and seventh most common cancers in the developed world. In s…
View article: Identification of HPV16 in suspected cases of cervical lesions and docking Study of its L1 protein with some natural inhibitors.
Identification of HPV16 in suspected cases of cervical lesions and docking Study of its L1 protein with some natural inhibitors. Open
Background The Human papillomavirus (HPV) causes sexually transmitted diseases. Among several types of HPV variants, HPV 16 is listed as a high-risk group, the primary cervical cancer etiologic agent, which causes life-threatening disease …
View article: A prospective study to compare the effectiveness of adjunctive rectal misoprostol or oxytocin titration in the prevention of primary post-partum haemorrhage in at risk patients
A prospective study to compare the effectiveness of adjunctive rectal misoprostol or oxytocin titration in the prevention of primary post-partum haemorrhage in at risk patients Open
Rectal misoprostol is as effective and safe as oxytocin when used as an adjunctive uterotonic in preventing primary post-partum haemorrhage in patients with risk factors for uterine atony after active management of third stage of labour.
View article: Annexin II as a Dengue Virus Serotype 2 Interacting Protein Mediating Virus Interaction on Vero Cells
Annexin II as a Dengue Virus Serotype 2 Interacting Protein Mediating Virus Interaction on Vero Cells Open
Recent evidence has demonstrated that dengue virus requires active filopodia formation for a successful infection. However, the cellular factor involved in the interaction has not been fully elucidated. We used a combination of virus overl…
View article: Sero-epidemiology of Contagious Ecthyma Based on Detection of IgG Antibody in Selected Sheep and Goats Farms in Malaysia
Sero-epidemiology of Contagious Ecthyma Based on Detection of IgG Antibody in Selected Sheep and Goats Farms in Malaysia Open
C ontagious ecthyma (CE) is an emerging, infectious and zoonotic viral disease of sheep and goat that is caused by CE virus belonging to the poxviridae family according to the classification of the international committee on taxonomy of vi…
View article: Molecular identification of dengue virus binding protein on filopodia of vero cells
Molecular identification of dengue virus binding protein on filopodia of vero cells Open
Despite much efforts to control dengue virus, there is still neither scientifically proven effective drug nor an effective internationally licensed vaccine to treat or control dengue. Recent evidence has demonstrated that dengue virus requ…