Ian Faragher
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View article: Colorectal cancer survivorship program at a single tertiary centre: has service provision changed after COVID-19?
Colorectal cancer survivorship program at a single tertiary centre: has service provision changed after COVID-19? Open
View article: Factors associated with diagnostic and treatment intervals in colorectal cancer: A linked data study
Factors associated with diagnostic and treatment intervals in colorectal cancer: A linked data study Open
This research aimed to assess the length of intervals before diagnosis and treatment for colorectal cancer in Australia using linked datasets, and to determine any factors associated with interval length. A colorectal cancer clinical regis…
View article: “Scoping” sustainability: rethinking sterile water use in colonoscopies
“Scoping” sustainability: rethinking sterile water use in colonoscopies Open
View article: Colorectal cancer survivorship program at a single tertiary centre :– Has service provision changed after Covid-19?
Colorectal cancer survivorship program at a single tertiary centre :– Has service provision changed after Covid-19? Open
Purpose Surveillance after colorectal cancer (CRC) resection is an important aspect of survivorship care. This study aimed to assess whether there were any changes to post-operative surveillance in non-metastatic CRC patients, pre and post…
View article: Accuracy of Baseline Magnetic Resonance Imaging for Staging Rectal Cancer Patients Proceeding Directly to Surgery
Accuracy of Baseline Magnetic Resonance Imaging for Staging Rectal Cancer Patients Proceeding Directly to Surgery Open
Background and Objectives High‐resolution magnetic resonance imaging (MRI) accuracy for staging preoperative rectal cancer varies across studies. We examined MRI accuracy for T‐ and N‐staging of rectal cancer compared with final histopatho…
View article: It's time to consider screening for anal cancer in high risk populations
It's time to consider screening for anal cancer in high risk populations Open
Community groups and medical bodies such as the US Center for Disease Control have called for establishment of screening programs for anal cancer in high-risk groups.1 Over 90% of anal squamous cell carcinoma (aSCC) is caused by human papi…
View article: Body composition assessment by artificial intelligence can be a predictive tool for short-term postoperative complications in Hartmann’s reversals
Body composition assessment by artificial intelligence can be a predictive tool for short-term postoperative complications in Hartmann’s reversals Open
Background Hartmann's reversal, a complex elective surgery, reverses and closes the colostomy in individuals who previously underwent a Hartmann's procedure due to colonic pathology like cancer or diverticulitis. It demands careful plannin…
View article: Artificial intelligence measured <scp>3D</scp> body composition to predict pathological response in rectal cancer patients
Artificial intelligence measured <span>3D</span> body composition to predict pathological response in rectal cancer patients Open
Background The treatment of locally advanced rectal cancer (LARC) is moving towards total neoadjuvant therapy and potential organ preservation. Of particular interest are predictors of pathological complete response (pCR) that can guide pe…
View article: Issue Information
Issue Information Open
View article: Body composition assessment by Artificial Intelligence can be a predictive tool for short-term postoperative complications in Hartmann’s reversals
Body composition assessment by Artificial Intelligence can be a predictive tool for short-term postoperative complications in Hartmann’s reversals Open
Background Hartmann’s reversal is a complex elective procedure that requires careful planning and patient optimisation to help reduce postoperative complications. Preoperative evaluation of body composition has been useful in identifying p…
View article: Issue Information
Issue Information Open
View article: Emerging trends in the prediction of pathological tumour response in rectal cancer following neoadjuvant therapy
Emerging trends in the prediction of pathological tumour response in rectal cancer following neoadjuvant therapy Open
The treatment landscape of locally advanced rectal cancer (LARC) is moving towards total neoadjuvant therapy and potential organ preservation. Multimodality neoadjuvant therapy (NAT) and surgery remain the standard-of-care for LARC, with c…
View article: Are health outcomes in the older colorectal cancer patients treated by curative intent surgery any different to the younger patients?
Are health outcomes in the older colorectal cancer patients treated by curative intent surgery any different to the younger patients? Open
Background Colorectal cancer poses a major burden. Its incidence increases with age and older patients with comorbidities have a higher likelihood of major complications. This study investigated the impact of age on health outcomes in colo…
View article: Current colorectal cancer chemotherapy dosing limitations and novel assessments to personalize treatments
Current colorectal cancer chemotherapy dosing limitations and novel assessments to personalize treatments Open
Management of colorectal cancer is becoming increasingly more complex, with current major treatment modalities now including surgery, radiotherapy, chemotherapy, targeted therapy and immunotherapy. In the era of personalized oncology, a re…
View article: Reversal of Hartmann's procedure: timelines, preoperative investigations and early outcomes. A single Australian institution's ten‐year experience
Reversal of Hartmann's procedure: timelines, preoperative investigations and early outcomes. A single Australian institution's ten‐year experience Open
Background Real‐world data on outcomes following Hartmann's reversal is necessary to help optimize the patient experience. We have explored the timing between the index operation and its reversal; what investigations were carried out prior…
View article: Is increasing nodal count associated with improved recurrence‐free and overall survival following standard right hemicolectomy for colon cancer?
Is increasing nodal count associated with improved recurrence‐free and overall survival following standard right hemicolectomy for colon cancer? Open
Background and Objectives Increasing lymph node harvest for right‐sided colon cancer is associated with improved overall survival (OS), but most relevant studies failed to report the extent of resection. We examined the association between…
View article: Biology and Clinical Implications of Fecal Occult Blood Test Screen-Detected Colorectal Cancer
Biology and Clinical Implications of Fecal Occult Blood Test Screen-Detected Colorectal Cancer Open
Background Fecal occult blood test (FOBT)–based screening for colorectal cancer (CRC) reduces mortality, with earlier stage at diagnosis a prominent feature. Other characteristics of FOBT screen-detected cancers and any implications for cl…
View article: Stage dependent recurrence patterns and post-recurrence outcomes in non-metastatic colon cancer
Stage dependent recurrence patterns and post-recurrence outcomes in non-metastatic colon cancer Open
In this community cohort we defined significant differences in recurrence patterns and post-resection survival by tumor stage, with a diminishing rate of recurrence over time. While recurrence rates were lower with stage I and II disease, …
View article: Implementation of an organ space infection prevention bundle reduces the rate of organ space infection after elective colorectal surgery
Implementation of an organ space infection prevention bundle reduces the rate of organ space infection after elective colorectal surgery Open
Background Surgical site infections (SSIs) are morbid and costly complications after elective colorectal surgery. SSI prevention bundles have been shown to reduce SSI in colorectal surgery, but their impact on organ space infections (OSI) …
View article: Anaemia and its impact on colorectal cancer patients: how can we better optimize surgical outcomes?
Anaemia and its impact on colorectal cancer patients: how can we better optimize surgical outcomes? Open
Background Anaemia is a common manifestation of colorectal cancer (CRC). However, appropriate workup prior to surgery and the effect of anaemia on outcomes have not been well defined. This study aimed to describe preoperative anaemia incid…
View article: Positive lateral pelvic lymph nodes in low rectal cancer: should we change our practice now?
Positive lateral pelvic lymph nodes in low rectal cancer: should we change our practice now? Open
Background The role of lateral lymph node dissection (LLND) in the treatment of patients with low rectal cancer with enlarged lateral lymph nodes (LLN+) is under investigation. Enthusiasm for LLND stems from a perceived reduction in local …
View article: The effect of smoking, obesity and diabetes on recurrence‐free and overall survival in patients with stage III colon cancer receiving adjuvant chemotherapy
The effect of smoking, obesity and diabetes on recurrence‐free and overall survival in patients with stage III colon cancer receiving adjuvant chemotherapy Open
Background The association between smoking, diabetes and obesity and oncological outcomes in patients with stage III colon cancer treated with surgery and adjuvant chemotherapy is unclear. Aim To evaluate whether smoking, obesity and diabe…
View article: Going loopy: using ScopeGuide to demonstrate incarceration of a colonoscope within an inguinal hernia
Going loopy: using ScopeGuide to demonstrate incarceration of a colonoscope within an inguinal hernia Open
View article: Patterns of surveillance for colorectal cancer: Experience from a single large tertiary institution
Patterns of surveillance for colorectal cancer: Experience from a single large tertiary institution Open
Aim Colorectal cancer surveillance is an essential part of care and should include clinical review and follow‐up investigations. There is limited information regarding postoperative surveillance and survivorship care in the Australian cont…
View article: Abstract Journal Colorectal Surgery
Abstract Journal Colorectal Surgery Open
Purpose: Peritoneal metastases confer the worst survival in patients with metastatic colorectal cancer.Current management options are limited; with treatment resistance and disease progression common.The development of organoids as a pre-c…
View article: Circulating Tumor DNA Analyses as Markers of Recurrence Risk and Benefit of Adjuvant Therapy for Stage III Colon Cancer
Circulating Tumor DNA Analyses as Markers of Recurrence Risk and Benefit of Adjuvant Therapy for Stage III Colon Cancer Open
Results suggest that ctDNA analysis after surgery is a promising prognostic marker in stage III colon cancer. Postchemotherapy ctDNA analysis may define a patient subset that remains at high risk of recurrence despite completing standard a…
View article: Overexpression of TP53 protein is associated with the lack of adjuvant chemotherapy benefit in patients with stage III colorectal cancer
Overexpression of TP53 protein is associated with the lack of adjuvant chemotherapy benefit in patients with stage III colorectal cancer Open
View article: Treatment of colonoscopic perforation: outcomes from a major single tertiary institution
Treatment of colonoscopic perforation: outcomes from a major single tertiary institution Open
Background The use of colonoscopy has been increasing in Australia. This case series describes management and outcomes of colonoscopic perforation managed by a single tertiary referral unit. Methods An analysis of 13 years (2003–2015) of p…
View article: Complete state‐wide outcomes in elective colon cancer surgery
Complete state‐wide outcomes in elective colon cancer surgery Open
Background Maintaining high standards in colon cancer surgery requires the measurement of quality indicators and the re‐allocation of resources to address deficiencies. We used state‐wide administrative data to determine the inpatient mort…
View article: PO-065 Assessment of prognostic models for stage II/III colon cancer: a hospital-based prospective cohort study
PO-065 Assessment of prognostic models for stage II/III colon cancer: a hospital-based prospective cohort study Open
Introduction Multiple predictors of colon cancer prognosis to aid treatment decisions have been proposed. However, it is unclear whether calculators trained on one population yield accurate predictions for another population with differen…