Ian A. Harris
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View article: Antinuclear antibody positivity in acute Epstein–Barr virus and cytomegalovirus infections
Antinuclear antibody positivity in acute Epstein–Barr virus and cytomegalovirus infections Open
Epstein-Barr virus (EBV) and cytomegalovirus (CMV) are herpesviruses presumed to trigger autoimmunity. This study assessed the association between acute EBV/CMV infection and antinuclear antibody (ANA) seropositivity. We retrospectively re…
View article: Global Carbon Budget 2025
Global Carbon Budget 2025 Open
Accurate assessment of anthropogenic carbon dioxide (CO2) emissions and their redistribution among the atmosphere, ocean, and terrestrial biosphere in a changing climate is critical to better understand the global carbon cycle, support the…
View article: Expectations about pain management after discharge from total hip and knee replacement surgery: a qualitative study with patients and prescribers
Expectations about pain management after discharge from total hip and knee replacement surgery: a qualitative study with patients and prescribers Open
Objective This study aimed to explore the perspectives of both patients and prescribers regarding analgesia after discharge following total hip or knee replacement surgeries, focusing on opioid use and the factors influencing patient and p…
View article: Spinal cord stimulation patterns of care, re‐interventions, and costs for private health insurers, Australia, 2011–22: a retrospective observational study
Spinal cord stimulation patterns of care, re‐interventions, and costs for private health insurers, Australia, 2011–22: a retrospective observational study Open
Objectives To investigate spinal cord stimulation patterns of care, the proportions of people who require unplanned surgical interventions after receiving definitive spinal cord stimulator implants, and the costs to private health insurers…
View article: Are Rates of Inpatient Rehabilitation Reduced for Robotic Assisted Total Knee Arthroplasty Compared With Computer Navigated Total Knee Arthroplasty?
Are Rates of Inpatient Rehabilitation Reduced for Robotic Assisted Total Knee Arthroplasty Compared With Computer Navigated Total Knee Arthroplasty? Open
Background Robotic assistance and computer navigation systems are increasingly being used for total knee arthroplasty (TKA) with demonstrated improvements in early functional outcomes relative to conventional instrumentation. Patients are …
View article: ARC (Australian Rotator Cuff) trial: study protocol for a randomised placebo-controlled trial comparing rotator cuff repair to no repair during arthroscopic shoulder surgery for people with shoulder pain and non-acute rotator cuff tears
ARC (Australian Rotator Cuff) trial: study protocol for a randomised placebo-controlled trial comparing rotator cuff repair to no repair during arthroscopic shoulder surgery for people with shoulder pain and non-acute rotator cuff tears Open
The trial is registered with the Australian New Zealand Clinical Trials Registry (ACTRN12620000789965) on 5 August 2020 and the WHO International Clinical Trials Registry Platform (universal trial number U1111-1251-6599).
View article: Kinematic alignment achieves a tibial joint line angle that is more parallel to the floor in single-leg stance than mechanical alignment
Kinematic alignment achieves a tibial joint line angle that is more parallel to the floor in single-leg stance than mechanical alignment Open
Aims Previous research on knee kinematics has demonstrated that achieving a tibial joint line angle (TJLA) parallel to the floor in the single-leg stance phase of gait may restore native knee kinematics and optimize compartmental compressi…
View article: ARC (Australian Rotator Cuff) trial: study protocol for a randomised placebo-controlled trial comparing rotator cuff repair to no repair during arthroscopic shoulder surgery for people with shoulder pain and non-acute rotator cuff tears
ARC (Australian Rotator Cuff) trial: study protocol for a randomised placebo-controlled trial comparing rotator cuff repair to no repair during arthroscopic shoulder surgery for people with shoulder pain and non-acute rotator cuff tears Open
Background Degenerative rotator cuff tears are common and are often treated with surgical repair. Randomised trials have not shown a clear advantage to surgery over non-surgical treatment but there have been no published placebo-controlled…
View article: The smallest worthwhile effect of surgery versus non-surgical treatments for sciatica: a benefit-harm trade-off study
The smallest worthwhile effect of surgery versus non-surgical treatments for sciatica: a benefit-harm trade-off study Open
People with sciatica would require discectomy to provide an additional 15% reduction in their leg pain beyond the expected 50% improvement in leg pain from non-surgical treatments in the short term to consider discectomy worthwhile. These …
View article: Statistical analysis plan for the Robotic-Assisted Surgery and Kinematic ALignment in total knee arthroplasty (RASKAL) registry-nested randomized trial
Statistical analysis plan for the Robotic-Assisted Surgery and Kinematic ALignment in total knee arthroplasty (RASKAL) registry-nested randomized trial Open
Aims There is uncertainty over whether robotic-assisted surgery (RAS) or kinematic alignment (KA) improves outcomes in total knee arthroplasty (TKA). The Robotic-Assisted Surgery and Kinematic ALignment in TKA trial (RASKAL) is a registry-…
View article: Global Carbon Budget 2024
Global Carbon Budget 2024 Open
Accurate assessment of anthropogenic carbon dioxide (CO2) emissions and their redistribution among the atmosphere, ocean, and terrestrial biosphere in a changing climate is critical to better understand the global carbon cycle, support the…
View article: Comparative Effectiveness of Different Opioid Regimens, in Daily Dose or Treatment Duration, Prescribed at Surgical Discharge: a Systematic Review and Meta-Analysis
Comparative Effectiveness of Different Opioid Regimens, in Daily Dose or Treatment Duration, Prescribed at Surgical Discharge: a Systematic Review and Meta-Analysis Open
Higher-dose opioids provide a slight reduction in immediate post-discharge pain intensity but may lead to more adverse events. Longer durations of opioid treatment are probably not more effective in reducing pain than shorter treatment dur…
View article: Factors influencing prosthesis selection and variation: a survey of orthopaedic surgeons in Australia
Factors influencing prosthesis selection and variation: a survey of orthopaedic surgeons in Australia Open
Background There is increasing demand for knee and hip arthroplasty with considerable health system cost implications. Despite the high surgical costs relating to the prosthesis used, little is known about which factors are most influentia…
View article: Performance of ChatGPT-4o in the diagnostic workup of fever among returning travellers requiring hospitalization: a validation study
Performance of ChatGPT-4o in the diagnostic workup of fever among returning travellers requiring hospitalization: a validation study Open
Background Febrile illness in returned travellers presents a diagnostic challenge in non-endemic settings. Chat generative pretrained transformer (ChatGPT) has the potential to assist in medical tasks, yet its diagnostic performance in cli…
View article: Development of a patient decision aid for people with chronic low back pain and degenerative disc disease considering lumbar fusion: A mixed-methods study
Development of a patient decision aid for people with chronic low back pain and degenerative disc disease considering lumbar fusion: A mixed-methods study Open
This study showed that our prototype patient decision aid is acceptable, useful, and prepares patients to make informed decisions about spinal fusion for chronic LBP and degenerative disc disease. Future studies will assess the clinical im…
View article: Effectiveness of a physiotherapist-led triage and treatment service on WAITing time for adults with musculoskeletal pain referred to Australian public hospital physiotherapy clinics: a protocol for the WAIT-less trial
Effectiveness of a physiotherapist-led triage and treatment service on WAITing time for adults with musculoskeletal pain referred to Australian public hospital physiotherapy clinics: a protocol for the WAIT-less trial Open
Introduction Musculoskeletal pain is the second leading cause of disease burden in Australia, and there is a need to investigate new models of care to cope with the increasing demand for health services. This paper describes the protocol f…
View article: A systematic review of qualitative studies examining barriers and facilitators to orthopaedic surgeon engagement with patient-reported outcome measures data
A systematic review of qualitative studies examining barriers and facilitators to orthopaedic surgeon engagement with patient-reported outcome measures data Open
Background Orthopaedic surgeon engagement with patient-reported outcome measures (PROMs) data has not been comprehensively evaluated, despite increasing uptake of orthopaedic PROMs programmes globally. The aim of this review was to systema…
View article: Describing randomization in trials included in systematic reviews in orthopaedic surgery
Describing randomization in trials included in systematic reviews in orthopaedic surgery Open
Aims Systematic reviews of randomized controlled trials (RCTs) are the highest level of evidence used to inform patient care. However, it has been suggested that the quality of randomization in RCTs in orthopaedic surgery may be low. This …
View article: PP42 Implementing A Sustainable Enhanced Recovery From Surgery Pathway After Hip And Knee Arthroplasty: A Budget Impact Analysis
PP42 Implementing A Sustainable Enhanced Recovery From Surgery Pathway After Hip And Knee Arthroplasty: A Budget Impact Analysis Open
Introduction Increasing resources are devoted to osteoarthritis surgical care in Australia annually, with significant expenditure attributed to hip and knee arthroplasties. Safe, efficient, and sustainable models of care are required. This…
View article: Global Carbon Budget 2024
Global Carbon Budget 2024 Open
Accurate assessment of anthropogenic carbon dioxide (CO2) emissions and their redistribution among the atmosphere, ocean, and terrestrial biosphere in a changing climate is critical to better understand the global carbon cycle, support the…
View article: Oral Nutritional Supplementation in Older Adults with a Hip Fracture—Findings from a Bi-National Clinical Audit
Oral Nutritional Supplementation in Older Adults with a Hip Fracture—Findings from a Bi-National Clinical Audit Open
Background/Objectives: Evidence-based guidelines and care standards recommend offering oral nutrition supplements to all older adults with hip fracture, not just those already malnourished. This study aimed to identify the proportion of in…
View article: Lifetime Cost-Effectiveness of Structured Education and Exercise Therapy for Knee Osteoarthritis in Australia
Lifetime Cost-Effectiveness of Structured Education and Exercise Therapy for Knee Osteoarthritis in Australia Open
Importance Structured education and exercise therapy programs have been proposed to reduce reliance on total knee replacement (TKR) surgery and improve health care sustainability. The long-term cost-effectiveness of these programs is uncle…
View article: Adherence to clinical care standards and mortality after hip fracture surgery in New South Wales, 2015–2018: a retrospective population‐based study
Adherence to clinical care standards and mortality after hip fracture surgery in New South Wales, 2015–2018: a retrospective population‐based study Open
Objectives To determine whether adherence to hip fracture clinical care quality indicators influences mortality among people who undergo surgery after hip fracture in New South Wales, both overall and by individual indicator. Study design …
View article: The smallest worthwhile effect on pain and function for rotator cuff repair surgery: a benefit-harm trade-off study
The smallest worthwhile effect on pain and function for rotator cuff repair surgery: a benefit-harm trade-off study Open
Background The smallest worthwhile effect (SWE) is the minimum benefit required in addition to that from a comparator, for an intervention to be considered worthwhile by patients. We aimed to estimate the SWE for rotator cuff repair (with …
View article: Unnecessary care in orthopaedic surgery
Unnecessary care in orthopaedic surgery Open
Unnecessary care, where the potential for harm exceeds the potential for benefit, is widespread in medical care. Orthopaedic surgery is no exception. This has significant implications for patient safety and health care expenditure. This na…
View article: The influence of implant factors on patient outcomes in primary total knee arthroplasty
The influence of implant factors on patient outcomes in primary total knee arthroplasty Open
Utilizing a fixed bearing or robotic assistance correlated with improved OKS scores, whereas highly crosslinked polyethylene or cemented femoral components were associated with improved pain scores. At six months, the use of IDI compared t…