Ian Purcell
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View article: Granulocyte Colony Stimulating Factor in the Prevention of Chemotherapy-Induced Neutropenia in Patients With Colorectal Cancer Receiving Trifluridine/Tipiracil: A Real-World UK Retrospective Review
Granulocyte Colony Stimulating Factor in the Prevention of Chemotherapy-Induced Neutropenia in Patients With Colorectal Cancer Receiving Trifluridine/Tipiracil: A Real-World UK Retrospective Review Open
Introduction Trifluridine-tipiracil (FTD/TPI) is approved as monotherapy and in combination with bevacizumab for the treatment of metastatic colorectal cancer (mCRC). This UK real-world retrospective analysis aimed to evaluate the use of g…
View article: Percutaneous Coronary Intervention in the UK: Recommendations of the British Cardiovascular Intervention Society
Percutaneous Coronary Intervention in the UK: Recommendations of the British Cardiovascular Intervention Society Open
Percutaneous techniques to treat obstructive coronary artery disease continue to evolve and the evidence base informing our practice is shared and summarised in international guidelines. In the UK, the British Cardiovascular Intervention S…
View article: Pullback Pressure Gradient—An Emerging Concept in Patients with Coronary Artery Disease
Pullback Pressure Gradient—An Emerging Concept in Patients with Coronary Artery Disease Open
Fractional flow reserve fractional flow reserve (FFR)-guided percutaneous coronary intervention (PCI) is currently recommended in the management of patients with stable coronary artery disease (CAD). Pullback pressure gradient (PPG) index …
View article: The role of arginine vasopressin in the pathophysiology of microvascular dysfunction after ST-elevation myocardial infarction
The role of arginine vasopressin in the pathophysiology of microvascular dysfunction after ST-elevation myocardial infarction Open
Background Coronary microvascular dysfunction (CMD) after ST-elevation myocardial infarction (STEMI), in part due to impaired vasomotor tone, predicts heart failure and mortality at one year. Arginine vasopressin (AVP) may be implicated in…
View article: P131 Transferring critically ill Covid-19 patients in ITU - A multidisciplinary training exercise
P131 Transferring critically ill Covid-19 patients in ITU - A multidisciplinary training exercise Open
Introduction During Covid-19 many staff members were redeployed to the Intensive Care Unit (ICU) with little opportunity to train in the new skills they would require. One such skill was the transfer of a critically ill, and contagious, pa…
View article: Effect of Pressure-controlled intermittent Coronary Sinus Occlusion (PiCSO) on infarct size in anterior STEMI: PiCSO in ACS study
Effect of Pressure-controlled intermittent Coronary Sinus Occlusion (PiCSO) on infarct size in anterior STEMI: PiCSO in ACS study Open
PiCSO, as an adjunct to pPCI, was associated with a lower infarct size at 5 days after anterior STEMI in a propensity score-matched population.
View article: Percutaneous coronary intervention for left main stem disease: Impact of diabetes mellitus on mortality
Percutaneous coronary intervention for left main stem disease: Impact of diabetes mellitus on mortality Open
Objectives We assessed the impact of diabetes mellitus (DM) on mortality after percutaneous coronary intervention (PCI) for left main stem (LMS) disease. Second, we compared mortality outcomes between non‐insulin treated (NITDM) and insuli…
View article: Smoking status and mortality outcomes following percutaneous coronary intervention
Smoking status and mortality outcomes following percutaneous coronary intervention Open
Objective The aim of this study was to assess the impact of smoking on short (30-day) and intermediate (30-day to 6-month) mortality following percutaneous coronary intervention (PCI). Background The effect of smoking on mortality post-PCI…
View article: 11 The association of frailty and coronary artery plaque composition in high-risk older patients with non-st elevation acute coronary syndrome
11 The association of frailty and coronary artery plaque composition in high-risk older patients with non-st elevation acute coronary syndrome Open
Introduction The association of frailty with vulnerable plaques and plaque composition in older patients following non-ST elevation acute coronary syndrome (NSTEACS) is not known. Methods 27 patients>70 years of age, admitted for invasive…
View article: 23 The association of cognitive impairment and coronary artery disease burden in older patients with non-st elevation acute coronary syndrome
23 The association of cognitive impairment and coronary artery disease burden in older patients with non-st elevation acute coronary syndrome Open
Introduction The relationship between cognition and complexity of coronary artery disease (CAD) measured by Syntax score and British Cardiovascular Intervention Society Jeopardy Score (BCIS JS) in older patients presenting with non ST elev…
View article: 66 Cognitive impairment is not associated with 30 day major adverse cardiovascular events in older (75 years) patients presenting with non-st elevation acute coronary syndrome: an evaluation from the icon1 study
66 Cognitive impairment is not associated with 30 day major adverse cardiovascular events in older (75 years) patients presenting with non-st elevation acute coronary syndrome: an evaluation from the icon1 study Open
Introduction Dementia is leading cause of death in the UK and shares many common risk factors with coronary artery disease. The relationship between cognition and major adverse cardiovascular events (MACE) in older patients presenting with…