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View article: Genetically Determined Inflammation‐Related Proteins in Asthma and Type‐2 Signatures
Genetically Determined Inflammation‐Related Proteins in Asthma and Type‐2 Signatures Open
Background Protein quantitative trait loci (pQTLs) remain underexplored in asthma but might provide valuable insights into the underlying molecular mechanisms. This study aimed to investigate associations between genetic variation and infl…
View article: Post COVID-19 among young adults– prevalence and associations with general health, stress, and lifestyle factors
Post COVID-19 among young adults– prevalence and associations with general health, stress, and lifestyle factors Open
Background The prevalence of post COVID-19 condition (PCC) after mild infection among young adults is largely unknown, as are its impact on health and lifestyle factors. Objective To assess the prevalence of PCC among young adults and its …
View article: Childhood atopic dermatitis is associated with cardiovascular risk factors in young adulthood—A population‐based cohort study
Childhood atopic dermatitis is associated with cardiovascular risk factors in young adulthood—A population‐based cohort study Open
Background Studies have indicated that atopic dermatitis (AD) is associated with an increased risk of cardiovascular disease (CVD). However, data are conflicting. Furthermore, the longitudinal effect of childhood AD on cardiovascular risk …
View article: Ambient air pollution exposure linked to long COVID among young adults: a nested survey in a population-based cohort in Sweden
Ambient air pollution exposure linked to long COVID among young adults: a nested survey in a population-based cohort in Sweden Open
The study received funding from the Swedish Research Council (grant no. 2020-01886, 2022-06340), the Swedish Research Council for Health, Working life and Welfare (FORTE grant no. 2017-01146), the Swedish Heart-Lung Foundation, Karolinska …
View article: Egg and milk exposure during pregnancy and food reactions in grandchildren
Egg and milk exposure during pregnancy and food reactions in grandchildren Open
To the Editor, The origins of food allergy and food-related symptoms are to a large extent not understood, despite their large impact on public health.1 Our aim was to evaluate whether avoidance of intake of egg and milk during the last tr…
View article: Exploring proteomic plasma biomarkers in eosinophilic and neutrophilic asthma
Exploring proteomic plasma biomarkers in eosinophilic and neutrophilic asthma Open
Background Few biomarkers identify eosinophilic and neutrophilic asthma beyond cell concentrations in blood or sputum. Finding novel biomarkers for asthma endotypes could give insight about disease mechanisms and guide tailored treatment. …
View article: Association of Short-term Air Pollution Exposure With SARS-CoV-2 Infection Among Young Adults in Sweden
Association of Short-term Air Pollution Exposure With SARS-CoV-2 Infection Among Young Adults in Sweden Open
The findings of this case-crossover study of Swedish young adults suggest that short-term exposure to particulate matter and BC was associated with increased risk of positive PRC test results for SARS-CoV-2, supporting the broad public hea…
View article: Lung function in young adulthood: differences between males and females with asthma
Lung function in young adulthood: differences between males and females with asthma Open
Background There are phenotypic differences in asthma in males and females. Differences in lung function between the sexes at the peak lung function level in young adulthood are so far not directly addressed. The aim of the present study w…
View article: Uncontrolled asthma from childhood to young adulthood associates with airflow obstruction
Uncontrolled asthma from childhood to young adulthood associates with airflow obstruction Open
Introduction Lung function development from childhood to young adulthood is important for lung health later in life. We investigated the association between asthma control and lung function from 8 to 24 years of age. Methods A total of 668…
View article: Inflammatory patterns in fixed airflow obstruction are dependent on the presence of asthma
Inflammatory patterns in fixed airflow obstruction are dependent on the presence of asthma Open
Rationale Fixed airflow obstruction (FAO) can complicate asthma. Inflammation is a proposed underlying mechanism. Objective Our aim in this cross-sectional investigation was to evaluate the blood leucocyte pattern and level of exhaled nitr…
View article: Blood eosinophil level and lung function trajectories: cross-sectional and longitudinal studies in European cohorts
Blood eosinophil level and lung function trajectories: cross-sectional and longitudinal studies in European cohorts Open
Background Elevated blood eosinophils have been associated with lower lung function and are believed to be associated with accelerated lung function decline. Method Blood eosinophils were measured in four cohorts: <45 years cohort within t…
View article: Inflammation in asthma: relation to symptomatology, exacerbations and lung function
Inflammation in asthma: relation to symptomatology, exacerbations and lung function Open
Asthma is an inflammatory disease in the airways. It is characterized by respiratory symptoms such as wheezing, variable airflow obstruction and impaired lung function development. A better understanding of the underlying inflammation is c…