İdil Esen
YOU?
Author Swipe
View article: Impaired IL-6-induced JAK-STAT signaling in CD4+ T cells associates with longer treatment duration in giant cell arteritis
Impaired IL-6-induced JAK-STAT signaling in CD4+ T cells associates with longer treatment duration in giant cell arteritis Open
Overall, in GCA, the percentages of in vitro IL-6-induced pSTAT3+CD4+T-cells likely reflect prior in vivo exposure to high IL-6 and may serve as a prognostic marker for GC-treatment duration and may assist improving personalized treatment …
View article: Immune signatures in chronic inflammatory diseases
Immune signatures in chronic inflammatory diseases Open
Giant cell arteritis (GCA) and polymyalgia rheumatica (PMR) are inflammatory rheumatic diseases that may develop with aging. GCA is one of the most common forms of vasculitis affecting large- and medium-sized blood vessels in elderly patie…
View article: Evidence for increased interferon type I activity in CD8+ T cells in giant cell arteritis patients
Evidence for increased interferon type I activity in CD8+ T cells in giant cell arteritis patients Open
Introduction Giant cell arteritis (GCA) is a vasculitis of the medium- and large-sized arteries. Interferon type I (IFN-I) is increasingly recognized as a key player in autoimmune diseases and might be involved in GCA pathogenesis, however…
View article: POS1440 EVIDENCE FOR INCREASED RESPONSIVENESS TO INTERFERON TYPE I IN CD8+ T CELLS IN PATIENTS WITH GIANT CELL ARTERITIS
POS1440 EVIDENCE FOR INCREASED RESPONSIVENESS TO INTERFERON TYPE I IN CD8+ T CELLS IN PATIENTS WITH GIANT CELL ARTERITIS Open
View article: AB0718 LEVELS OF PHOSPHO-STAT3 ASSOCIATE WITH TREATMENT DURATION IN GIANT CELL ARTERITIS
AB0718 LEVELS OF PHOSPHO-STAT3 ASSOCIATE WITH TREATMENT DURATION IN GIANT CELL ARTERITIS Open
View article: Metabolic features and glucocorticoid-induced comorbidities in patients with giant cell arteritis and polymyalgia rheumatica in a Dutch and Danish cohort
Metabolic features and glucocorticoid-induced comorbidities in patients with giant cell arteritis and polymyalgia rheumatica in a Dutch and Danish cohort Open
Objectives Giant cell arteritis (GCA) and polymyalgia rheumatica (PMR) are age-associated inflammatory diseases that frequently overlap. Both diseases require long-term treatment with glucocorticoids (GCs), often associated with comorbidit…
View article: Tocilizumab in Giant Cell Arteritis: Better Understanding the Benefits
Tocilizumab in Giant Cell Arteritis: Better Understanding the Benefits Open
Disclosure Form Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author f…
View article: Humoral and cellular SARS-CoV-2 vaccine responses in patients with giant cell arteritis and polymyalgia rheumatica
Humoral and cellular SARS-CoV-2 vaccine responses in patients with giant cell arteritis and polymyalgia rheumatica Open
Objectives Giant cell arteritis (GCA) and polymyalgia rheumatica (PMR) are overlapping autoinflammatory diseases affecting people over 50 years. The diseases are treated with immunosuppressive drugs such as prednisolone, methotrexate, lefl…
View article: Comment on: Plasma Pyruvate Kinase M2 as a marker of vascular inflammation in giant cell arteritis: reply
Comment on: Plasma Pyruvate Kinase M2 as a marker of vascular inflammation in giant cell arteritis: reply Open
View article: Plasma Pyruvate Kinase M2 as a marker of vascular inflammation in giant cell arteritis
Plasma Pyruvate Kinase M2 as a marker of vascular inflammation in giant cell arteritis Open
Objectives GCA is a large vessel vasculitis in which metabolically active immune cells play an important role. GCA diagnosis is based on CRP/ESR and temporal artery biopsies (TABs), in combination with 18F-fluorodeoxyglucose ([18F]FDG)-PET…
View article: Functionally Heterogenous Macrophage Subsets in the Pathogenesis of Giant Cell Arteritis: Novel Targets for Disease Monitoring and Treatment : Novel Targets for Disease Monitoring and Treatment
Functionally Heterogenous Macrophage Subsets in the Pathogenesis of Giant Cell Arteritis: Novel Targets for Disease Monitoring and Treatment : Novel Targets for Disease Monitoring and Treatment Open
Giant cell arteritis (GCA) is a granulomatous large-vessel vasculitis that affects adults above 50 years of age. In GCA, circulating monocytes are recruited to the inflamed arteries. With cues from the vascular microenvironment, they diffe…
View article: Functionally Heterogenous Macrophage Subsets in the Pathogenesis of Giant Cell Arteritis: Novel Targets for Disease Monitoring and Treatment
Functionally Heterogenous Macrophage Subsets in the Pathogenesis of Giant Cell Arteritis: Novel Targets for Disease Monitoring and Treatment Open
Giant cell arteritis (GCA) is a granulomatous large-vessel vasculitis that affects adults above 50 years of age. In GCA, circulating monocytes are recruited to the inflamed arteries. With cues from the vascular microenvironment, they diffe…
View article: ARID4B is critical for mouse embryonic stem cell differentiation towards mesoderm and endoderm, linking epigenetics to pluripotency exit
ARID4B is critical for mouse embryonic stem cell differentiation towards mesoderm and endoderm, linking epigenetics to pluripotency exit Open
Distinct cell types emerge from embryonic stem cells through a precise and coordinated execution of gene expression programs during lineage commitment. This is established by the action of lineage specific transcription factors along with …