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View article: Personalized Intervention to Improve Medication Adherence for Persons with Multiple Sclerosis
Personalized Intervention to Improve Medication Adherence for Persons with Multiple Sclerosis Open
This study demonstrated reasonable retention and initial efficacy of a combined psycho-education and MI protocol for PwRRMS to enhance medication adherence to DMT. To maintain the change, a more sustained intervention is required.
View article: Treatment Persistence of Apremilast Among Patients with Psoriatic Arthritis
Treatment Persistence of Apremilast Among Patients with Psoriatic Arthritis Open
In this large observational retrospective cohort of patients treated with apremilast, a relatively low drug persistence was observed with 6-month and 1-year survival rates of 50.3% and 31.3%, respectively. Treatment discontinuation was mai…
View article: Predictors and Long-Term Prognostic Significance of Acute Renal Function Change in Patients Who Underwent Surgical Aortic Valve Replacement
Predictors and Long-Term Prognostic Significance of Acute Renal Function Change in Patients Who Underwent Surgical Aortic Valve Replacement Open
There are few reports on short-term changes in renal function after surgical aortic valve replacement, and data are scarce regarding its impact on long-term outcomes. This is a retrospective study of patients who underwent isolated aortic …
View article: Association of CYP2C19 Polymorphism With Proton Pump Inhibitors Effectiveness and With Fractures in Real‐Life: Retrospective Cohort Study
Association of CYP2C19 Polymorphism With Proton Pump Inhibitors Effectiveness and With Fractures in Real‐Life: Retrospective Cohort Study Open
Symptom refractoriness of patients treated with proton pump inhibitors (PPIs) might be explained by polymorphism in CYP2C19. This is a retrospective cohort study in which we used the computerized database of Clalit Health Services to compo…
View article: High Dimensional Analyses of Circulating Immune Cells in Psoriatic Arthritis Detects Elevated Phosphorylated STAT3
High Dimensional Analyses of Circulating Immune Cells in Psoriatic Arthritis Detects Elevated Phosphorylated STAT3 Open
Psoriatic arthritis (PsA) is a chronic inflammatory arthritis, affecting up to 40% of patients with psoriasis. Constitutive expression by CD4+ T cells of an active form of STAT3, a signal transducer and transcription factor, has been shown…
View article: Implementation of the Treat-to-Target Concept in Evaluation of Psoriatic Arthritis Patients
Implementation of the Treat-to-Target Concept in Evaluation of Psoriatic Arthritis Patients Open
Background: The treat-to-target approach was recently adopted for psoriatic arthritis (PsA) management. Objective: To assess the implementation of the “treat-to-target” (T2T) concept in daily management of PsA by use of composite scores of…
View article: Research Productivity among Plastic Surgeons in the State of Israel: h-index and M-quotient Assessment
Research Productivity among Plastic Surgeons in the State of Israel: h-index and M-quotient Assessment Open
Background: The h -index has been proven in the US and Canada to be a solid tool to assess the quality and impact of individual scientific work in the field of plastic surgery. M-quotient is an additional metric that mitigates the h -index…
View article: Global longitudinal strain and long-term outcome in patients presenting to the emergency department with suspected acute coronary syndrome
Global longitudinal strain and long-term outcome in patients presenting to the emergency department with suspected acute coronary syndrome Open
Aims: We have previously shown that 2-dimentional strain is not a useful tool for ruling out acute coronary syndrome (ACS) in the emergency department (ED). The aim of the present study was to determine whether in patients with suspected A…
View article: Causes of mortality in a department of cardiology over a 15-year period
Causes of mortality in a department of cardiology over a 15-year period Open
The profile of the patients who died did not change significantly over the 15-year study period. Age of admitted patients was higher in later years of the study. The leading cause of admission was ACS and the leading causes of death were c…
View article: Treatment Persistence of Biologics among patients with Psoriatic Arthritis
Treatment Persistence of Biologics among patients with Psoriatic Arthritis Open
Background Persistence of biologic therapy in psoriatic arthritis (PsA) patients is an important factor in individualized patient treatment planning and healthcare policy and guideline development. . Objective To estimate the persistence o…
View article: Inflammatory Bowel Disease in Children With Systemic Juvenile Idiopathic Arthritis
Inflammatory Bowel Disease in Children With Systemic Juvenile Idiopathic Arthritis Open
Objective The incidence of inflammatory bowel disease (IBD) in juvenile idiopathic arthritis (JIA) is higher than in the general pediatric population. However, reports of IBD in the systemic JIA (sJIA) subtype are limited. We sought to cha…
View article: Increased Prevalence of Systemic Lupus Erythematosus Comorbidity in Patients With Psoriatic Arthritis: A Population-based Case-control Study
Increased Prevalence of Systemic Lupus Erythematosus Comorbidity in Patients With Psoriatic Arthritis: A Population-based Case-control Study Open
Objective. To assess the prevalence of systemic lupus erythematosus (SLE) in a psoriatic arthritis (PsA) cohort and to compare it to the general population using the database of a large healthcare provider. Methods. We analyzed the databas…
View article: Treat-to-target concept implementation for evaluating rheumatoid arthritis patients in daily practice
Treat-to-target concept implementation for evaluating rheumatoid arthritis patients in daily practice Open
Objective: We aimed to assess the implementation of the treat-to-target (T2T) concept in rheumatoid arthritis (RA) patients in daily practice. Methods: All RA patients visiting one of the 7 academic medical centers in Israel in June 2015 w…
View article: Delayed Colonoscopy Following a Positive Fecal Test Result and Cancer Mortality
Delayed Colonoscopy Following a Positive Fecal Test Result and Cancer Mortality Open
Background A fecal test followed by diagnostic colonoscopy for a positive result is a widely endorsed screening strategy for colorectal cancer (CRC). However, the relationship between the time delay from the positive test to the follow-up …
View article: Postoperative Treatment of Distal Radius Fractures Using Sensorimotor Rehabilitation
Postoperative Treatment of Distal Radius Fractures Using Sensorimotor Rehabilitation Open
Background Sensorimotor and specifically proprioception sense has been used in rehabilitation to treat neurological and joint injuries. These feedback loops are not well understood or implemented in wrist treatment. We observed a temporary…
View article: Distinct Wrist Patterns Founded on Measurements in Plain Radiographs
Distinct Wrist Patterns Founded on Measurements in Plain Radiographs Open
Background In joints, structure dictates function and consequently pathology. Interpreting wrist structure is complicated by the existence of multiple joints and variability in bone shapes and anatomical patterns in the wrist. Previous stu…
View article: Utility of the iPhone 4 Gyroscope Application in the Measurement of Wrist Motion
Utility of the iPhone 4 Gyroscope Application in the Measurement of Wrist Motion Open
Background: Measurement of wrist range of motion (ROM) is important to all aspects of treatment and rehabilitation of upper extremity conditions. Recently, gyroscopes have been used to measure ROM and may be more precise than manual evalua…