Ignacio Ara
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View article: Cost-effectiveness of a multicomponent training programme for older adults with decreased functional capacity: An economic evaluation
Cost-effectiveness of a multicomponent training programme for older adults with decreased functional capacity: An economic evaluation Open
ClinicalTrial.gov identifier: NCT03831841 DATE OF REGISTRATION: 6/02/2019 (Last update 02/07/2020).
View article: Low relative sit-to-stand power is associated with history of falls and fractures, prospective hospitalization, and all-cause mortality in older adults from the Toledo study for healthy aging
Low relative sit-to-stand power is associated with history of falls and fractures, prospective hospitalization, and all-cause mortality in older adults from the Toledo study for healthy aging Open
Low relative STS power was associated with history of hip fractures in women, whereas in men it was associated with history of falls and all-type fractures. Low relative STS power predicted hospitalizations in women but not in men. In both…
View article: Serum lncRNAs NEAT1, PVT1 and H19 as novel biomarkers for sarcopenia diagnosis and treatment response
Serum lncRNAs NEAT1, PVT1 and H19 as novel biomarkers for sarcopenia diagnosis and treatment response Open
Sarcopenia, the loss of muscle mass and function generally associated to age, leads to increased dependence and mortality in older adults. Despite its clinical significance, unclear molecular mechanisms hinder the development of universal …
View article: Low Relative Sit‐to‐Stand Power Is Associated With the Development of Adverse Health Outcomes: A 5‐Year Longitudinal Study
Low Relative Sit‐to‐Stand Power Is Associated With the Development of Adverse Health Outcomes: A 5‐Year Longitudinal Study Open
Background Relative sit‐to‐stand (STS) power has emerged as a key biomarker of aging due to its strong association with adverse health outcomes such as frailty or disability. Thus, this study aimed to evaluate the association between low b…
View article: Role of high-intensity exercise interventions in the management of frailty: a short systematic review
Role of high-intensity exercise interventions in the management of frailty: a short systematic review Open
This study aimed to summarize the current evidence on the impact of high-intensity exercise training interventions on frailty and physical function in older adults. A systematic review of controlled trials involving frail and prefrail olde…
View article: Cut‐Off Points for Low Relative 30‐s Sit‐to‐Stand Power and Their Associations With Adverse Health Conditions
Cut‐Off Points for Low Relative 30‐s Sit‐to‐Stand Power and Their Associations With Adverse Health Conditions Open
Background Despite muscle power derived from the 5‐rep sit‐to‐stand (STS) test having been demonstrated to be a valuable biomarker in older individuals, there is limited information regarding muscle power derived from the 30‐s STS test, a …
View article: Open-source code for analysis of the lifetime total physical activity questionnaire (LTPAQ)
Open-source code for analysis of the lifetime total physical activity questionnaire (LTPAQ) Open
Advancing research to understand the impact of lifetime physical activity patterns on health is essential. While some progress on the topic has been made, further research is nevertheless warranted. Openly accessible operational resources …
View article: Supervised Versus Unsupervised Exercise for the Improvement of Physical Function and Well-Being Outcomes in Older Adults: A Systematic Review and Meta-analysis of Randomized Controlled Trials
Supervised Versus Unsupervised Exercise for the Improvement of Physical Function and Well-Being Outcomes in Older Adults: A Systematic Review and Meta-analysis of Randomized Controlled Trials Open
Background Unsupervised exercise intervention (UNSUP) appears to be a practical and beneficial strategy for older adults, although its feasibility and effectiveness compared to supervised exercise intervention (SUP) remains unknown. We aim…
View article: Effects of multicomponent training and HMB supplementation on disability, cognitive and physical function in institutionalized older adults aged over 70 years: a cluster-randomized controlled trial
Effects of multicomponent training and HMB supplementation on disability, cognitive and physical function in institutionalized older adults aged over 70 years: a cluster-randomized controlled trial Open
The Vivifrail exercise program was effective in improving cognitive and physical function, and muscle power in nursing home residents, while HMB supplementation did not provide additional benefits when combined with exercise. These results…
View article: Effects of 12 weeks of power-oriented resistance training plus high-intensity interval training on metabolic syndrome factors in older people with COPD
Effects of 12 weeks of power-oriented resistance training plus high-intensity interval training on metabolic syndrome factors in older people with COPD Open
Objectives To assess the effects of an exercise training program combining power-oriented resistance training (RT) and high-intensity interval training (HIIT) on metabolic syndrome (MetS) markers in older people with COPD. Methods Twenty-n…
View article: Effects of a multicomponent training followed by a detraining period on metabolic syndrome profile of older adults
Effects of a multicomponent training followed by a detraining period on metabolic syndrome profile of older adults Open
ClinicalTrial.gov identifier: NCT03831841.
View article: Longitudinal Changes in the Body Composition of Non-Institutionalized Spanish Older Adults after 8 Years of Follow-Up: The Effects of Sex, Age, and Organized Physical Activity
Longitudinal Changes in the Body Composition of Non-Institutionalized Spanish Older Adults after 8 Years of Follow-Up: The Effects of Sex, Age, and Organized Physical Activity Open
Aging leads to physiological changes affecting body composition, mediated by lifestyle. However, the effectiveness of organized physical activities (OPAs) in attenuating or delaying these age-related transformations remains an area of limi…
View article: The role of supervision and motivation during exercise on physical and mental health in older adults: A study protocol for a randomized controlled Trial (PRO-Training project)
The role of supervision and motivation during exercise on physical and mental health in older adults: A study protocol for a randomized controlled Trial (PRO-Training project) Open
Background Although supervised exercise is frequently recommended for older adults, its superiority over unsupervised exercise remains uncertain. Furthermore, whether motivational techniques could help to enhance the effectiveness of the l…
View article: Cardiopulmonary Exercise Testing in the Context of an Aerosol-Borne Infectious Disease: Comparison between the Jaeger Oxycon Pro and the COSMED Quark RMR Metabolic Carts
Cardiopulmonary Exercise Testing in the Context of an Aerosol-Borne Infectious Disease: Comparison between the Jaeger Oxycon Pro and the COSMED Quark RMR Metabolic Carts Open
Several factors, such as internal algorithm, sensor technology, and obsolescence might skew outcomes when comparing different gas analysers measurements during CPET. Besides aerosol borne infectious disease are a source of contamination du…
View article: Multicomponent Training Improves the Quality of Life of Older Adults at Risk of Frailty
Multicomponent Training Improves the Quality of Life of Older Adults at Risk of Frailty Open
Achieving a high quality of life in older adults can be difficult if they have limited physical function. The aims of this study were to evaluate the relationship between baseline values and variations in body composition, fitness, and nut…
View article: Comparison between the Jaeger Oxycon Pro and the COSMED Quark RMR Metabolic Carts for Cardiopulmonary Exercise Testing in the Context of an Aerosol-Borne Infectious Disease
Comparison between the Jaeger Oxycon Pro and the COSMED Quark RMR Metabolic Carts for Cardiopulmonary Exercise Testing in the Context of an Aerosol-Borne Infectious Disease Open
Several factors, such as internal algorithm, sensor technology, use of antibacterial filters or obsolescence, might explain the differences among computerised metabolic carts when measuring gas exchange parameters during cardiopulmonary ex…
View article: Power-oriented resistance training combined with high-intensity interval training in pre-frail and frail older people: comparison between traditional and cluster training set configurations on the force–velocity relationship, physical function and frailty
Power-oriented resistance training combined with high-intensity interval training in pre-frail and frail older people: comparison between traditional and cluster training set configurations on the force–velocity relationship, physical function and frailty Open
Objectives To analyse the force–velocity relationship changes in response to two different training programmes differing in the set configuration (cluster vs. traditional), and their impact on physical function and frailty in pre-frail and…
View article: Residual effects of 12 weeks of power‐oriented resistance training plus high‐intensity interval training on muscle dysfunction, systemic oxidative damage, and antioxidant capacity after 10 months of training cessation in older people with <scp>COPD</scp>
Residual effects of 12 weeks of power‐oriented resistance training plus high‐intensity interval training on muscle dysfunction, systemic oxidative damage, and antioxidant capacity after 10 months of training cessation in older people with <span>COPD</span> Open
Objective This study aimed to assess the residual effects of a 12‐week concurrent training program (power training + high‐intensity interval training) in older adults with chronic obstructive pulmonary disease (COPD). Methods A total of 21…
View article: Optimization of <scp>VO<sub>2</sub></scp> and <scp>VCO<sub>2</sub></scp> outputs for the calculation of resting metabolic rate using a portable indirect calorimeter
Optimization of <span>VO<sub>2</sub></span> and <span>VCO<sub>2</sub></span> outputs for the calculation of resting metabolic rate using a portable indirect calorimeter Open
This study aimed to compare the Cosmed K5 portable indirect calorimeter, using the mixing chamber mode and face mask, with a stationary metabolic cart when measuring the resting metabolic rate (RMR) and to derive fitting equations if discr…
View article: Patterns of Dietary Blood Markers Are Related to Frailty Status in the FRAILOMIC Validation Phase
Patterns of Dietary Blood Markers Are Related to Frailty Status in the FRAILOMIC Validation Phase Open
The influence of nutritional factors on frailty syndrome is still poorly understood. Thus, we aimed to confirm cross-sectional associations of diet-related blood biomarker patterns with frailty and pre-frailty statuses in 1271 older adults…