Ignacio Izeddin
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Bottom-up iterative anomalous diffusion detector (BI-ADD) Open
In recent years, the segmentation of short molecular trajectories with varying diffusive properties has drawn particular attention of researchers, since it allows studying the dynamics of a particle. In the past decade, machine learning me…
View article: Nano-resolved sensing of 3D electromagnetic fields via single emitters' extreme variation of enhanced spontaneous emission
Nano-resolved sensing of 3D electromagnetic fields via single emitters' extreme variation of enhanced spontaneous emission Open
Controlling quantum light-matter interactions at scales smaller than the diffraction limit at the single quantum emitter level is a critical challenge to the goal of advancing quantum technologies. We introduce a novel material platform th…
Bottom-up Iterative Anomalous Diffusion Detector (BI-ADD) Open
In recent years, the segmentation of short molecular trajectories with varying diffusive properties has drawn particular attention of researchers, since it allows studying the dynamics of a particle. In the past decade, machine learning me…
EVE is an open modular data analysis software for event-based localization microscopy Open
Event-based sensors (EBS), or neuromorphic vision sensors, offer a novel approach to imaging by recording light intensity changes asynchronously, unlike conventional cameras that capture light over fixed exposure times. This capability res…
Single-emitter super-resolved imaging of radiative decay rate enhancement in dielectric gap nanoantennas Open
High refractive index dielectric nanoantennas strongly modify the decay rate via the Purcell effect through the design of radiative channels. Due to their dielectric nature, the field is mainly confined inside the nanostructure and in the …
3D single-molecule super-resolution imaging of microfabricated multiscale fractal substrates for self-referenced cell imaging Open
Microstructures arrayed over a substrate have shown increasing interest due to their ability to provide advanced 3D cellular models, which open new possibilities for cell culture, proliferation, and differentiation. Still, the mechanisms b…
3D‐Architected Alkaline‐Earth Perovskites Open
3D ceramic architectures are captivating geometrical features with an immense demand in optics. In this work, an additive manufacturing (AM) approach for printing alkaline‐earth perovskite 3D microarchitectures is developed. The approach e…
Label-free virus-antibody interaction monitoring in real time by common-path interferometry Open
Viruses can affect all life forms, raising concerns about virus detection and quantification of small nanoparticles. In this paper we use a label-free, full-field, incoherently illuminated common path interferometric method to detect, trac…
Event-based vision sensor enables fast and dense single-molecule localization microscopy Open
Single-molecule localization microscopy (SMLM) is often hampered by the fixed frame rate of the acquisition. Here, we present an alternative new approach to data acquisition and processing based on an affordable event-based sensor. This ty…
Long wave infrared wavefront sensing through a thin diffuser Open
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Additive Manufacturing of 3D Luminescent ZrO<sub>2</sub>:Eu<sup>3+</sup> Architectures Open
Implementation of more refined structures at the nano to microscale is expected to advance applications in optics and photonics. This work presents the additive manufacturing of 3D luminescent microarchitectures emitting light in the visib…
Long Wave Infrared Wavefront Reconstruction Through Complex Media Open
A novel broadband infrared (IR) speckle imaging system with a thin scatterer and an uncooled microbolometric camera is employed to encode wavefront phase variations as local speckle deformations. The phase reconstruction from speckle shift…
View article: Super-resolution imaging: when biophysics meets nanophotonics
Super-resolution imaging: when biophysics meets nanophotonics Open
Probing light–matter interaction at the nanometer scale is one of the most fascinating topics of modern optics. Its importance is underlined by the large span of fields in which such accurate knowledge of light–matter interaction is needed…
Infrared phase imaging using complex scattering media Open
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Epigenetic rewriting at centromeric DNA repeats leads to increased chromatin accessibility and chromosomal instability Open
Background Centromeric regions of human chromosomes contain large numbers of tandemly repeated α-satellite sequences. These sequences are covered with constitutive heterochromatin which is enriched in trimethylation of histone H3 on lysine…
Epigenetic rewriting at centromeric DNA repeats leads to increased chromatin accessibility and chromosomal instability Open
Centromeric regions of human chromosomes contain large numbers of tandemly repeated α-satellite sequences. These sequences are covered with constitutive heterochromatin which is enriched in trimethylation of histone H3 on lysine 9 (H3K9me3…
Anomalous Subdiffusion in Living Cells: Bridging the Gap Between Experiments and Realistic Models Through Collaborative Challenges Open
The life of a cell is governed by highly dynamical microscopic processes. Two notable examples are the diffusion of membrane receptors and the kinetics of transcription factors governing the rates of gene expression. Different fluorescence…
Relocating single-molecules in super-resolved fluorescence lifetime images near a plasmonic nanostructure Open
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Relocating Single Molecules in Super-Resolved Fluorescence Lifetime Images near a Plasmonic Nanostructure Open
Single-molecule localization microscopy is a powerful technique with vast potential to study light-matter interactions at the nanoscale. Nanostructured environments can modify the fluorescence emission of single molecules, and the induced …
Cramér-Rao analysis of lifetime estimations in time-resolved fluorescence microscopy Open
Measuring the lifetime of fluorescent emitters by time-correlated single photon counting (TCSPC) is a routine procedure in many research areas spanning from nanophotonics to biology. The precision of such measurement depends on the number …
Fisher information theory for optimised lifetime estimations in time-resolved fluorescence microscopy Open
Measuring the lifetime of fluorescent emitters by time-correlated single photon counting (TCSPC) is a routine procedure in many research areas spanning from nanophotonics to biology. The precision of such measurement depends on the number …
Multi-scale tracking reveals scale-dependent chromatin dynamics after DNA damage Open
The dynamic organization of genes inside the nucleus is an important determinant for their function. Using fast DNA tracking microscopy in Saccharomyces cerevisiae cells and improved analysis of mean-squared displacements, we quantified DN…
Chromatin mobility after DNA damage is modified to enhance long distance explorations and minimize local resampling Open
The dynamic organization of genes inside the nucleus is an important determinant for their function. Using ultra-fast microscopy in S. cerevisiae cells and improved analysis of mean square displacements, we quantified DNA motion at time sc…