Ignacio Roa
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View article: Visualization of the dentogingival junction using micro‐plastination technique
Visualization of the dentogingival junction using micro‐plastination technique Open
Plastination has revolutionized the field of anatomy and research by providing biosecurity and enabling the long‐term preservation of biological material, ranging from entire bodies to individual organs and even micron sections. The dentog…
View article: Striated Musculature: Embryonic and Fetal Development
Striated Musculature: Embryonic and Fetal Development Open
The different embryological origins of striated muscle tissue make it an interesting tissue but at the same time difficult to understand, this is how the musculature of the face comes from the first pharyngeal arch, on the other hand. The …
View article: Celecoxib: Antiangiogenic and Antitumoral Action
Celecoxib: Antiangiogenic and Antitumoral Action Open
Angiogenesis, a process by which new blood vessels are generated from pre-existing ones, is significantly compromised in tumor development, given that due to the nutritional need of tumor cells, pro-angiogenic signals will be generated to …
View article: Respiratory Muscles: Structure, Function and Relationship with the ACE Gene. A Brief Morphofunctional Communication
Respiratory Muscles: Structure, Function and Relationship with the ACE Gene. A Brief Morphofunctional Communication Open
Pulmonary ventilation is a mechanical process in which the respiratory muscles act in coordination to maintain the oxygenation of the organism. Any alteration in the performance of these muscles may reduce the effectiveness of the process.…
View article: Immunohistochemical Markers in the Differential Diagnosis of Melanoma and Nevus in Humans
Immunohistochemical Markers in the Differential Diagnosis of Melanoma and Nevus in Humans Open
Immunohistochemistry allows in situ detection of cell and extracellular components through specific antibodies. The objective was to compare the immunohistochemical expression patterns of the S-100, HMB-45 and MART-1 proteins for different…
View article: Monosodium Glutamate Alters the Function and Morphology of the Parotid Gland in Sprague Dawley Rats
Monosodium Glutamate Alters the Function and Morphology of the Parotid Gland in Sprague Dawley Rats Open
Monosodium glutamate (MSG) is a flavor enhancer widely used in the food industry, with obesogenic properties, in addition to causing alterations in the oral cavity. The aim of the study was to observe the morphofunctional changes in the pa…
View article: Types I and III Parotid Collagen Variations and Serum Biochemical Parameters in Obese Rats Exposed to Monosodium Glutamate
Types I and III Parotid Collagen Variations and Serum Biochemical Parameters in Obese Rats Exposed to Monosodium Glutamate Open
The objective of this study was to describe the effects of monosodium glutamate on the collagen of the parotid gland in an obesity model. 18 newborn male Sprague Dawley rats were used (first control group; second group of MSG1: 4 mg/g of m…
View article: Parotid Gland Comparative Microscopic Anatomy
Parotid Gland Comparative Microscopic Anatomy Open
The frequent use of animal models in biomedical research means that the anatomy or histology of the animals is constantly analyzed so the results obtained can be extrapolated to human tissues; therefore, knowledge of the structures studied…
View article: Juxtaoral organ: an anatomical finding to be considered
Juxtaoral organ: an anatomical finding to be considered Open
The juxtaoral organ (JOO) is a vestigial anatomical structure which is not usuallydescribed in lectures and classic texts of general histology and oral histology, despiteit being included in the "Terminologia Histologica: International ter…
View article: Obesity, salivary glands and oral pathology.
Obesity, salivary glands and oral pathology. Open
Obesity has reached pandemic proportions in recent years. Not only adults suffer from the disease, but increasingly children and young people. One of the main causes of overweight and obesity is excessive food intake, in particular heavily…
View article: Obesity, salivary glands and oral pathology
Obesity, salivary glands and oral pathology Open
Obesity has reached pandemic proportions in recent years. Not only adults suffer from the disease, but increasingly children and young people. One of the main causes of overweight and obesity is excessive food intake, in particular heavily…
View article: miRNAs in the Odontogenesis Process
miRNAs in the Odontogenesis Process Open
MicroRNAs (miRNAs) are a class of small RNA molecules noncoding to proteins, which regulate gene expression at post-transcriptional level by binding to specific sequences within target genes. miRNAs have been recognized as important regula…
View article: Foetal Development in Mammals
Foetal Development in Mammals Open
During the fetal period are carried out a series of necessary changes, which prepare the fetus for extrauterine life, culminating embryonic development, leading to this physiological maturation of tissues, organs and systems, along with a …
View article: Basic Concepts in Tumor Angiogenesis
Basic Concepts in Tumor Angiogenesis Open
The transformation of normal cells into cancer encompasses a complex series of events, such as genetic disorders, aberrant cell cycles, changes in the phenotype and in cell adhesion, inhibition of apoptosis and generation of new blood vess…
View article: Clarification of Terminologia Embryologica: Gartner Duct
Clarification of Terminologia Embryologica: Gartner Duct Open
The use of eponyms is still a practice used among clinical, despite the efforts of the morphological community uprooting of medical language. The reason of this study is to make a clarification regarding Terminology Embryologica Gartner du…
View article: Adherence to International Anatomical Terminology by a Government-implemented High School Biology Science Education Curriculum
Adherence to International Anatomical Terminology by a Government-implemented High School Biology Science Education Curriculum Open
Chilean science education curriculum is standardized and issued by the Ministry of Education (MINEDUC). This study contributes to science education analyzing a government implemented high school biology curriculum and its adherence to the …
View article: Perikymata: A Non-existent Term. A Scientific Literature Invention? Terminology Analysis and Proposal
Perikymata: A Non-existent Term. A Scientific Literature Invention? Terminology Analysis and Proposal Open
The constant and gradual apposition of the enamel during odontogenesis forms different histological structures on the tooth, including the perikymata, which appear on the crown surface as ridges between two imbrication lines. Although they…
View article: Angiogenesis and Tumor Progression Inhibition of Cyclooxygenase-2 Selective Inhibitor Celecoxib Associated with Poly (lactic-co-glycolic acid) in Tumor Cell Line Resistant to Chemotherapy
Angiogenesis and Tumor Progression Inhibition of Cyclooxygenase-2 Selective Inhibitor Celecoxib Associated with Poly (lactic-co-glycolic acid) in Tumor Cell Line Resistant to Chemotherapy Open
© 2017, Universidad de la Frontera. All rights reserved. Although, antineoplastic therapies have now been developed reduction of tumor progression, it is necessary to find new therapeutic alternatives to suppress angiogenesis. Thus celecox…
View article: Anatomical Variations of the Foramen Transversarium in Cervical Vertebrae
Anatomical Variations of the Foramen Transversarium in Cervical Vertebrae Open
The cervical vertebrae are recognized mainly by the presence of the foramen transversarium, which is crossed by the vertebral artery and vein, accompanied by sympathetic fibers. The main objective of this study was to observe and describe …