Ignacio Roura
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View article: Circadian alterations in isolated REM sleep behavior disorder: associations with clinical, glymphatic and, dopaminergic imaging markers
Circadian alterations in isolated REM sleep behavior disorder: associations with clinical, glymphatic and, dopaminergic imaging markers Open
Alterations in sleep–wake patterns are well-recognized features of overt alpha-synucleinopathies. However, their presence in prodromal stages, characterised by isolated REM sleep behavior disorder (iRBD), remains controversial, and their a…
View article: Cortical macro- and microstructural changes in isolated rapid eye movement sleep behavior disorder
Cortical macro- and microstructural changes in isolated rapid eye movement sleep behavior disorder Open
Cortical mean diffusivity (cMD), a marker of cortical microstructural changes in neurodegenerative disorders, remains unexplored in isolated REM sleep behavior disorder (iRBD), a prodromal stage of Lewy body (LB) diseases. Its relationship…
View article: Altered Intra‐ and Inter‐Network Resting‐State Functional Connectivity is Associated with Neuropsychological Functioning and Clinical Symptoms in Patients with Isolated Rapid Eye Movement Sleep Behavior Disorder
Altered Intra‐ and Inter‐Network Resting‐State Functional Connectivity is Associated with Neuropsychological Functioning and Clinical Symptoms in Patients with Isolated Rapid Eye Movement Sleep Behavior Disorder Open
Background Isolated rapid‐eye movement (REM) sleep behavior disorder (iRBD) is characterized by abnormal behaviors in REM sleep and is considered as a prodromal symptom of alpha‐synucleinopathies. Resting‐state functional magnetic resonanc…
View article: Structural brain changes in post-COVID condition and its relationship with cognitive impairment
Structural brain changes in post-COVID condition and its relationship with cognitive impairment Open
It has been estimated that ∼4% of individuals infected with SARS-CoV-2 will be diagnosed with post-COVID condition. Previous studies have evidenced the presence of cognitive dysfunction and structural brain changes in infected individuals;…
View article: Cortical Macro‐ and Microstructural Changes in Parkinson's Disease with Probable Rapid Eye Movement Sleep Behavior Disorder
Cortical Macro‐ and Microstructural Changes in Parkinson's Disease with Probable Rapid Eye Movement Sleep Behavior Disorder Open
Background Evidence regarding cortical atrophy patterns in Parkinson's disease (PD) with probable rapid eye movement sleep behavior disorder (RBD) (PD‐pRBD) remains scarce. Cortical mean diffusivity (cMD), as a novel imaging biomarker high…