Igor Kagan
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View article: Probing the staying power of chemogenetics
Probing the staying power of chemogenetics Open
A study that monitored the expression and function of designer receptors called DREADDs in macaque monkeys for a period of three years demonstrates that they are effective in long-term studies of nonhuman primates.
View article: L-arginine Results in an Artificial Increase in Creatinine
L-arginine Results in an Artificial Increase in Creatinine Open
L-arginine is a commonly available over-the-counter supplement. We report a 65-year-old man with a history of benign prostatic hyperplasia, hypertension, and obstructive sleep apnea who had an elevated serum creatinine level and normal cys…
View article: Dyadic Interaction Platform: A novel tool to study transparent social interactions
Dyadic Interaction Platform: A novel tool to study transparent social interactions Open
Studies of social cognition examine how organisms process and act on the presence, intentions, actions, and behavioural outcomes of others in social contexts. Many real-life social interactions unfold during direct face-to-face contact and…
View article: Dyadic Interaction Platform: A novel tool to study transparent social interactions
Dyadic Interaction Platform: A novel tool to study transparent social interactions Open
Studies of social cognition examine how organisms process and act on the presence, intentions, actions, and behavioural outcomes of others in social contexts. Many real-life social interactions unfold during direct face-to-face contact and…
View article: Fixation shifts in a novel “no-report” binocular rivalry paradigm induce saccade-related perceptual switches
Fixation shifts in a novel “no-report” binocular rivalry paradigm induce saccade-related perceptual switches Open
No-report paradigms help to avoid report-related confounds in conscious perception studies. A novel no-report binocular rivalry paradigm by Hesse and Tsao (2020) tracks conscious content using eye position as subjects follow fixation point…
View article: Continuous dynamics of cooperation and competition in social decision-making
Continuous dynamics of cooperation and competition in social decision-making Open
Real-life social interactions often unfold continuously and involve dynamic cooperation and competition, yet most studies rely on discrete games that do not capture the adaptive and graded nature of continuous sensorimotor decisions. To ad…
View article: Dyadic Interaction Platform: A novel tool to study transparent social interactions
Dyadic Interaction Platform: A novel tool to study transparent social interactions Open
Studies of social cognition examine how organisms process and act on the presence, intentions, actions, and behavioural outcomes of others in social contexts. Many real-life social interactions unfold during direct face-to-face contact and…
View article: Optic Ataxia in Patients with Thalamic Lesions
Optic Ataxia in Patients with Thalamic Lesions Open
Lesions in parietal cortex can strongly impair visually guided reach-grasping behaviour. A specific reaching deficit termed ‘Optic Ataxia’ (OA) occurs when eye and hand position are dissociated. Optic ataxia has typically been studied in p…
View article: Fixation shifts in a novel “no-report” binocular rivalry paradigm induce saccade-related perceptual switches
Fixation shifts in a novel “no-report” binocular rivalry paradigm induce saccade-related perceptual switches Open
No-report paradigms help to avoid report-related confounds in conscious perception studies. A novel no-report binocular rivalry paradigm by Hesse and Tsao (2020) tracks conscious content using eye position as subjects follow fixation point…
View article: Optic ataxia in patients with thalamic lesions
Optic ataxia in patients with thalamic lesions Open
Lesions in the parietal cortex can strongly impair visually guided reach-grasping behaviour. A specific reaching deficit termed ‘optic ataxia’ (OA) occurs when eye and hand position are dissociated. OA has typically been studied in patient…
View article: Modality-specific and modality-general representations of subjective value in frontal cortex
Modality-specific and modality-general representations of subjective value in frontal cortex Open
Neuroeconomics theories propose that the value associated with diverse rewards or reward-predicting stimuli is encoded along a common reference scale, irrespective of their sensory properties. However, in a dynamic environment with changin…
View article: Confidence over competence: Real-time integration of social information in human continuous perceptual decision-making
Confidence over competence: Real-time integration of social information in human continuous perceptual decision-making Open
Human perceptual decision-making is susceptible to social influences. To determine if and how individuals opportunistically integrate real-time social information about noisy stimuli into their judgment, we tracked perceptual accuracy and …
View article: Confidence over competence: Real-time integration of social information in human continuous perceptual decision-making
Confidence over competence: Real-time integration of social information in human continuous perceptual decision-making Open
Human perception is susceptible to social influences. To determine if and how individuals opportunistically integrate real-time social information about noisy stimuli into their judgment, we tracked perceptual accuracy and confidence in so…
View article: Confidence over competence: Real-time integration of social information in human continuous perceptual decision-making
Confidence over competence: Real-time integration of social information in human continuous perceptual decision-making Open
Human perceptual decision-making is susceptible to social influences. To determine if and how individuals opportunistically integrate real-time social information about noisy stimuli into their judgment, we tracked perceptual accuracy and …
View article: Dorsal pulvinar inactivation leads to spatial selection bias without perceptual deficit
Dorsal pulvinar inactivation leads to spatial selection bias without perceptual deficit Open
The dorsal pulvinar has been implicated in visuospatial attentional and perceptual confidence processing. Pulvinar lesions in humans and monkeys lead to spatial neglect symptoms, including an overt spatial saccade bias during free choices.…
View article: Using camera-guided electrode microdrive navigation for precise 3D targeting of macaque brain sites
Using camera-guided electrode microdrive navigation for precise 3D targeting of macaque brain sites Open
Spatial accuracy in electrophysiological investigations is paramount, as precise localization and reliable access to specific brain regions help the advancement of our understanding of the brain’s complex neural activity. Here, we introduc…
View article: The contribution of sensory information asymmetry and bias of attribution to egocentric tendencies in effort comparison tasks
The contribution of sensory information asymmetry and bias of attribution to egocentric tendencies in effort comparison tasks Open
When comparing themselves with others, people often evaluate their own behaviors more favorably. This egocentric tendency is often categorized as a bias of attribution, with favorable self-evaluation resulting from differing explanations o…
View article: Little scientists & social apprentices: Active word learning in dynamic social contexts using a transparent dyadic interaction platform
Little scientists & social apprentices: Active word learning in dynamic social contexts using a transparent dyadic interaction platform Open
Previous tablet studies indicate that children learn object labels better through active initiation rather than passive observation. However, as children typically learn object labels through interactions with familiar partners, this study…
View article: Decision-making processes in perceptual learning depend on effectors
Decision-making processes in perceptual learning depend on effectors Open
Visual perceptual learning is traditionally thought to arise in visual cortex. However, typical perceptual learning tasks also involve systematic mapping of visual information onto motor actions. Because the motor system contains both effe…
View article: Dorsal pulvinar inactivation leads to spatial selection bias without perceptual deficit
Dorsal pulvinar inactivation leads to spatial selection bias without perceptual deficit Open
The dorsal pulvinar has been implicated in visuospatial attentional and perceptual confidence processing. Pulvinar lesions in humans and monkeys lead to spatial neglect symptoms, including an overt spatial saccade bias during free choices.…
View article: Visual, delay, and oculomotor timing and tuning in macaque dorsal pulvinar during instructed and free choice memory saccades
Visual, delay, and oculomotor timing and tuning in macaque dorsal pulvinar during instructed and free choice memory saccades Open
Causal perturbations suggest that primate dorsal pulvinar plays a crucial role in target selection and saccade planning, though its basic neuronal properties remain unclear. Some functional aspects of dorsal pulvinar and interconnected fro…
View article: Human and macaque pairs employ different coordination strategies in a transparent decision game
Human and macaque pairs employ different coordination strategies in a transparent decision game Open
Many real-world decisions in social contexts are made while observing a partner’s actions. To study dynamic interactions during such decisions, we developed a setup where two agents seated face-to-face to engage in game-theoretical tasks o…
View article: Dorsal pulvinar inactivation leads to spatial selection bias without perceptual deficit
Dorsal pulvinar inactivation leads to spatial selection bias without perceptual deficit Open
The dorsal pulvinar has been implicated in visuospatial attentional and perceptual confidence processing. Pulvinar lesions in humans and monkeys lead to spatial neglect symptoms, including an overt spatial saccade bias during free choices.…
View article: Modality-specific and modality-general representations of subjective value in frontal cortex
Modality-specific and modality-general representations of subjective value in frontal cortex Open
Standard neuroeconomics theories state that the value of different classes of stimuli, for instance the hedonic value of food versus music, is transformed to a common reference scale that is independent of their sensory properties. However…
View article: Author response: Human and macaque pairs employ different coordination strategies in a transparent decision game
Author response: Human and macaque pairs employ different coordination strategies in a transparent decision game Open
Article Figures and data Abstract Editor's evaluation eLife digest Introduction Results Discussion Materials and methods Appendix 1 Data availability References Decision letter Author response Article and author information Metrics Abstrac…