Igor Lima Maldonado
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View article: Automated Generation of Exploratory Test Cases Using Prompt Chaining and Reflective Evaluation
Automated Generation of Exploratory Test Cases Using Prompt Chaining and Reflective Evaluation Open
Exploratory testing uncovers latent defects, but the design of Exploratory Test Cases (ETC) is largely manual, incurring high costs, reliance on expert knowledge, and limited reproducibility. We propose IGEX, a fully automated approach to …
View article: Microsurgical Anatomy of Periventricular White Matter from the Endoventricular Perspective
Microsurgical Anatomy of Periventricular White Matter from the Endoventricular Perspective Open
Fiber dissection through ependyma removal is an effective method for studying anatomic relationships with adjacent white matter bundles, important for developing a precise anatomic mental picture necessary for effective and safe brain surg…
View article: Dysgraphia Following the Resection of a Left Parietal Glioma
Dysgraphia Following the Resection of a Left Parietal Glioma Open
We report herein the case of a 41-year-old man operated on for a small inferior parietal lobule ganglioglioma with a sleep-awake-sleep protocol and language mapping to avoid major speech disorders. Postoperatively, however, writing disturb…
View article: A road map to manual segmentation of cerebral structures
A road map to manual segmentation of cerebral structures Open
Manual segmentation is an essential tool in the researcher's technical arsenal. It is a frequent practice necessary for image analysis in many protocols, especially in neuroimaging and comparative brain anatomy. In the framework of emergen…
View article: Correlação da expressão imunoistoquímica de β-catenina, CDX2 e c-MYC com a agressividade no osteossarcoma
Correlação da expressão imunoistoquímica de β-catenina, CDX2 e c-MYC com a agressividade no osteossarcoma Open
Introdução: Osteossarcoma é neoplasia maligna agressiva, de origem mesenquimal, encontrado frequentemente em regiões metafisárias de ossos longos. A sobrevida geral em 5 anos é de aproximadamente 65%, sendo as metástases pulmonares as prin…
View article: Cicatrização de defeitos periostais na calvária entre dois tipos de membranas produzidas por meio de bioengenharia: estudo em coelhos
Cicatrização de defeitos periostais na calvária entre dois tipos de membranas produzidas por meio de bioengenharia: estudo em coelhos Open
Introdução: Simultaneamente ao desenvolvimento de novos biomateriais, abundantes modalidades cirúrgicas têm sido propostas, com a finalidade de promover adequada regeneração de defeitos ósseos, sem proporcionar fenestrações ou deiscências.…
View article: Direct Inside-Out Observation of Superficial White Matter Fasciculi in the Human Brain
Direct Inside-Out Observation of Superficial White Matter Fasciculi in the Human Brain Open
Background: Recent methodological advances in the study of the cerebral white matter have left short association fibers relatively underexplored due to their compact and juxtacortical nature, which represent significant chall…
View article: Multimodal study of multilevel pulvino-temporal connections: a new piece in the puzzle of lexical retrieval networks
Multimodal study of multilevel pulvino-temporal connections: a new piece in the puzzle of lexical retrieval networks Open
Advanced methods of imaging and mapping the healthy and lesioned brain have allowed for the identification of the cortical nodes and white matter tracts supporting the dual neurofunctional organization of language networks in a dorsal phon…
View article: Determinants and Clinical Relevance of Iodine Contrast Extravasation after Endovascular Thrombectomy: A Dual-Energy CT Study
Determinants and Clinical Relevance of Iodine Contrast Extravasation after Endovascular Thrombectomy: A Dual-Energy CT Study Open
ICE evaluated with DECT is a relatively frequent finding after EVT, present in almost one-third of patients. Lower admission ASPECTS, higher glycemia, and high contrast volume injected per procedure were associated with ICE. We also found …
View article: Paraffin embedding of the whole human cerebral hemisphere to assess arterial distribution territories
Paraffin embedding of the whole human cerebral hemisphere to assess arterial distribution territories Open
Commonly used to decode the human brain's structural complexity, ex vivo dissection focuses on a given structure or region but cannot depict the whole brain organization (for example, its arterial distribution territories). Where dissectio…
View article: The prey's perspective on the rise of predatory publishing
The prey's perspective on the rise of predatory publishing Open
View article: Using ex vivo arterial injection and dissection to assess white matter vascularization
Using ex vivo arterial injection and dissection to assess white matter vascularization Open
Advances in the techniques for assessing human cerebral white matter have recently contributed to greater attention to structural connectivity. Yet, little is known about the vascularization of most white matter fasciculi and the fascicula…
View article: Depicting the anatomy of the gyral white matter: <i>ubi sumus? quo vadimus?</i>
Depicting the anatomy of the gyral white matter: <i>ubi sumus? quo vadimus?</i> Open
A cerebral gyrus is made up of an external layer of folded cortex and an inner core of white matter. The architecture of the core has specific features that make it distinct from the white matter of the deep brain regions. Limited external…
View article: Anatomical study of the carotid‐trigeminal interface: The missing link in the trigeminovascular system?
Anatomical study of the carotid‐trigeminal interface: The missing link in the trigeminovascular system? Open
The trigeminal system is considered a prominent actor in brain nociceptive innervation. The trigeminovascular system is mainly composed of pseudounipolar neurons located within the trigeminal ganglion, whose dendrites originate in cerebral…
View article: Avoiding vascular complications in insular glioma surgery – A microsurgical anatomy study and critical reflections regarding intraoperative findings
Avoiding vascular complications in insular glioma surgery – A microsurgical anatomy study and critical reflections regarding intraoperative findings Open
Introduction Vascular lesions in insular glioma surgery can severely impact patients' quality of life. This study aims to present the results of our dissections and authors’ reflections on the insular vascular anatomy. Matherials …
View article: Fibravasc: a method to assess the vascularization of main white matter fiber tracts
Fibravasc: a method to assess the vascularization of main white matter fiber tracts Open
Advances in the techniques for assessing human cerebral white matter have recently contributed to greater attention to structural connectivity. Yet, little is known about the vascularization of most white matter fasciculi and the fascicula…
View article: Safety of Oral P2Y12 Inhibitors in Interventional Neuroradiology: Current Status and Perspectives
Safety of Oral P2Y12 Inhibitors in Interventional Neuroradiology: Current Status and Perspectives Open
In the field of interventional neuroradiology, antiplatelet agents are commonly used to prepare patients before the implantation of permanent endovascular materials. Among the available drugs, clopidogrel is the most frequently used one, b…
View article: Relevance of Brain Regions' Eloquence Assessment in Patients With a Large Ischemic Core Treated With Mechanical Thrombectomy
Relevance of Brain Regions' Eloquence Assessment in Patients With a Large Ischemic Core Treated With Mechanical Thrombectomy Open
This study provides Class II evidence that, in patients with AIS and LIC, considering the functional eloquence of the infarct location improves prediction of disability status at 3 months.
View article: Cerebral white matter vasculature: still uncharted?
Cerebral white matter vasculature: still uncharted? Open
White matter vasculature plays a major role in the pathophysiology of permanent neurological deficits following a stroke or progressive cognitive alteration related to small vessel disease. Thus, knowledge of the complex vascularization an…
View article: Characterization of limbic system connectivity through fiber dissection and diffusion imaging techniques
Characterization of limbic system connectivity through fiber dissection and diffusion imaging techniques Open
This is the final version of the following article : Characterization of limbic system connectivity through fiber dissection and diffusion imaging techniques, which has been published in final form at https://www.lestudium-ias.com/content/…
View article: Child pial arteriovenous fistula of the conus medullaris presenting with spinal cord venous congestion: Case report and literature review
Child pial arteriovenous fistula of the conus medullaris presenting with spinal cord venous congestion: Case report and literature review Open
View article: Composition and organization of the sagittal stratum in the human brain: a fiber dissection study
Composition and organization of the sagittal stratum in the human brain: a fiber dissection study Open
OBJECTIVE The sagittal stratum is divided into two layers. In classic descriptions, the stratum sagittale internum corresponds to optic radiations (RADs), whereas the stratum sagittale externum corresponds to fibers of the inferior longitu…
View article: A novel 3D nanofibre scaffold conserves the plasticity of glioblastoma stem cell invasion by regulating galectin-3 and integrin-β1 expression
A novel 3D nanofibre scaffold conserves the plasticity of glioblastoma stem cell invasion by regulating galectin-3 and integrin-β1 expression Open
Glioblastoma Multiforme (GBM) invasiveness renders complete surgical resection impossible and highly invasive Glioblastoma Initiating Cells (GICs) are responsible for tumour recurrence. Their dissemination occurs along pre-existing fibrill…
View article: Global Perspectives on Task Shifting and Task Sharing in Neurosurgery
Global Perspectives on Task Shifting and Task Sharing in Neurosurgery Open
View article: Task-Shifting and Task-Sharing in Neurosurgery: An International Survey of Current Practices in Low- and Middle-Income Countries
Task-Shifting and Task-Sharing in Neurosurgery: An International Survey of Current Practices in Low- and Middle-Income Countries Open
View article: NITINOL-based actuator for device control even in high-field MRI environment
NITINOL-based actuator for device control even in high-field MRI environment Open
Marco Kalmar, Axel Boese, Ivan Maldonado, Rainer Landes, Michael FriebeIntelligente Katheter Inka, Otto-von-Guericke University Magdeburg, Magdeburg, GermanyCorrespondence: Marco Kalmar Otto-von-Guericke-University, Universitaetsplatz 2, M…
View article: Inpatient trunk exercises after recent stroke: An update meta-analysis of randomized controlled trials
Inpatient trunk exercises after recent stroke: An update meta-analysis of randomized controlled trials Open
The introduction of trunk-based inpatient training protocols brings short-term benefits in trunk performance and balance in stroke patients.
View article: Prévention de l’AVC ischémique
Prévention de l’AVC ischémique Open
View article: Stereoscopic Images from Computed Tomography Angiograms
Stereoscopic Images from Computed Tomography Angiograms Open
View article: “Please don't move”: Cone-beam computed tomography and obstructive sleep apnea hypopnea syndrome
“Please don't move”: Cone-beam computed tomography and obstructive sleep apnea hypopnea syndrome Open