Explanipedia

Clinical Efficacy and Pharmacokinetics of Antivenom Viperfav® in Vipera ammodytes ammodytes Envenomation Open

Tihana Kurtović, Mojca Dobaja Borak, Damjan Grenc, Adrijana Leonardi, Igor Križaj , et al. · 2025

Background: In Europe, Vipera ammodytes ammodytes (Vaa, nose-horned viper) is considered the most venomous of the European vipers. The antivenom Viperfav®, composed of polyvalent equine F(ab′)2 fragments, is effective against Vipera aspis,…

BURNOUT SYNDROME OF NURSES/TECHNICIANS IN THE COVID-19 PANDEMIC AT UNIVERSITY CLINICAL HOSPITAL MOSTAR Open

Marija Vidović, Boris Lukšić · 2024

Introduction: Burnout syndrome results from chronic stress at work combined with ineffective coping with stress. Medical workers belong to the occupations with the highest percentages of burnout syndrome, which has been further increased b…

A pilot sentinel surveillance system to monitor treatment and treatment outcomes of chronic hepatitis B and C infections in clinical centres in three European countries, 2019 Open

Anthony Nardone, Lina Nerlander, Erika Duffell, Marta Valenciano, Marı́a Buti , et al. · 2023

Background The World Health Organization European Action Plan 2020 targets for the elimination of viral hepatitis are that > 75% of eligible individuals with chronic hepatitis B (HBV) or hepatitis C (HCV) are treated, of whom > 90% achieve…

Intravenous Vipera berus Venom-Specific Fab Fragments and Intramuscular Vipera ammodytes Venom-Specific F(ab’)2 Fragments in Vipera ammodytes-Envenomed Patients Open

Tihana Kurtović, Svjetlana Karabuva, Damjan Grenc, Mojca Dobaja Borak, Igor Križaj , et al. · 2021

Vipera ammodytes (V. ammodytes) is the most venomous European viper. The aim of this study was to compare the clinical efficacy and pharmacokinetic values of intravenous Vipera berus venom-specific (paraspecific) Fab fragments (ViperaTAb) …

Strategies to eliminate hepatitis C in Croatia, a modelling study Open

Sarah Blach, C Hrvatskoj, Studija Modeliranja, Adriana Vince, Ellen Dugan , et al. · 2020

Background: Since a 2016 analysis on the epidemiology and disease burden of HCV in Croatia, the HCV treatment paradigm has shifted substantially.Fibrosis restrictions were removed, and the number of patients treated tripled.With these enco…

Anisakis Sensitization in the Croatian fish processing workers: Behavioral instead of occupational risk factors? Open

Ana Jerončić, Diana Nonković, Anamarija Vrbatović, Jerko Hrabar, Ivana Bušelić , et al. · 2020

Vancomycin-Resistant Enterococcus faecium Colonization and Clostridium difficile Infection in a Hematologic Patient Open

Ivana Goić-Barišić, Marina Radić, Anita Novak, Žana Rubić, Nataša Boban , et al. · 2020

Vancomycin-resistant enterococci (VRE), especially Enterococcus faecium, have emerged as significant nosocomial pathogens and patients with impaired host defenses are at a particular risk of VRE infection. The most common occurrence…

Usefulness of presepsin as diagnostic and prognostic marker of sepsis in daily clinical practice Open

Matjaž Jereb, Matej Mavrič, Miha Skvarč, Alja Drobnic, Špela Dolenc , et al. · 2019

Introduction: Sepsis represents a major cause of morbidity and mortality in critically ill patients. Early diagnosis and appropriate treatment have a crucial influence on survival. The aim of this study was to evaluate the diagnostic and p…

Thrombocytopenic purpura following envenomation by the nose-horned viper (Vipera ammodytes ammodytes) Open

Boris Lukšić, Svjetlana Karabuva, Joško Markić, Branka Polić, Tanja Kovačević , et al. · 2018

Rationale: Two clinical cases are reported of envenomation by the nose-horned viper ( Vipera ammodytes ammodytes ) venom of a 9-year-old boy and of an 84-year-old woman. Patient concerns: Both patients had been bitten on their extremities …

Historical epidemiology of hepatitis C virus in select countries—volume 4 Open

Abderrahmane Maaroufi, Adriana Vince, Sayed Himatt, Rosmawati Mohamed, James Fung , et al. · 2017

Summary Due to the introduction of newer, more efficacious treatment options, there is a pressing need for policy makers and public health officials to develop or adapt national hepatitis C virus ( HCV ) control strategies to the changing …

Strategies to manage hepatitis C virus infection disease burden—Volume 4 Open

Ding‐Shinn Chen, Waseem Hamoudi, B. Mustapha, Jennifer E. Layden, Alexander Nersesov , et al. · 2017

Summary The hepatitis C virus ( HCV ) epidemic was forecasted through 2030 for 17 countries in Africa, Asia, Europe, Latin America and the Middle East, and interventions for achieving the Global Health Sector Strategy on viral hepatitis ta…

The present and future disease burden of hepatitis C virus infections with today's treatment paradigm: Volume 4 Open

Henry Lik‐Yuen Chan, C. J. Chen, O. Omede, Jehad Al Qamish, Khalid Al Naamani , et al. · 2017

Summary Factors influencing the morbidity and mortality associated with viremic hepatitis C virus (HCV) infection change over time and place, making it difficult to compare reported estimates. Models were developed for 17 countries (Bahrai…

First case of imported chikungunya infection in Croatia, 2016 Open

Boris Lukšić, Nenad Pandak, Edita Drazic-Maras, Svjetlana Karabuva, Mislav Radić , et al. · 2017

In recent years, several European countries reported cases of imported chikungunya infection. We present the first imported clinically manifested chikungunya fever in Croatia. A 27-year-old woman returned to Croatia on 21 March 2016, after…

Perinatal risk factors in newborns with gastrointestinal perforation Open

Sandra Prgomet, Boris Lukšić, Zenon Pogorelić, Ivo Jurić, Vesna Čapkun , et al. · 2017

GIP in newborns is mostly disease of infants with birth weight below 10^th percentile according to gestational age. GIP occurs more often in infants with anemia.

Real-time two-dimensional shear wave ultrasound elastography of the liver is a reliable predictor of clinical outcomes and the presence of esophageal varices in patients with compensated liver cirrhosis Open

Ivica Grgurević, Tomislav Bokun, Sanda Mustapić, Vladimir Trkulja, Renata Heinzl , et al. · 2015

This is the first evaluation of RT-2D-SWE as a prognostic tool in LC. Although preliminary and gathered in a limited sample, our data emphasize the potential of LS to be a reliable predictor of clinical outcomes and the presence of EV in L…

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