Ilan Halperin
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View article: Meta genetic analysis of melon sweetness
Meta genetic analysis of melon sweetness Open
Key message Through meta-genetic analysis of Cucumis melo sweetness, we expand the description of the complex genetic architecture of this trait. Integration of extensive new results with published QTL data provides an outline towards cons…
View article: Practice variation in surgical treatment for lumbar degenerative disc disease: exploring regional and hospital factors influencing surgical rates
Practice variation in surgical treatment for lumbar degenerative disc disease: exploring regional and hospital factors influencing surgical rates Open
The presence of significant, unwarranted variation in treatment suggests that clinical decision making also depends on where patients live instead of what they need and prefer. Historically, high practice variation in surgical treatment fo…
View article: Impact of evidence-based guidelines on healthcare utilisation and costs for disc related sciatica in the Netherlands: a population-based, cross-sectional study
Impact of evidence-based guidelines on healthcare utilisation and costs for disc related sciatica in the Netherlands: a population-based, cross-sectional study Open
Objective The aim of this study was to assess the impact of high-quality evidence supporting surgical treatment of lumbar disc herniation (LDH) on healthcare practice in the Netherlands by examining changes in healthcare utilisation, inclu…
View article: The diagnostic accuracy of spirometry as screening tool for adult patients with a benign subglottic stenosis
The diagnostic accuracy of spirometry as screening tool for adult patients with a benign subglottic stenosis Open
Background There is a considerable diagnostic delay in the diagnosis ‘benign acquired subglottic stenosis in adults’ (SGS, diagnosed by the reference standard, i.e. laryngo- or bronchoscopy). Patients are frequently misdiagnosed since symp…
View article: Practice Variation in Surgical Treatment for Lumbar Degenerative Disc Disease: Exploring Regional and Hospital Factors Influencing Surgical Rates
Practice Variation in Surgical Treatment for Lumbar Degenerative Disc Disease: Exploring Regional and Hospital Factors Influencing Surgical Rates Open
Introduction: The presence of significant, unwarranted variation in treatment suggests that clinical decision making also depends on where patients live instead of what they need and prefer. Historically, high practice variation in surgica…
View article: Pan‐genome and multi‐parental framework for high‐resolution trait dissection in melon ( <i>Cucumis melo</i> )
Pan‐genome and multi‐parental framework for high‐resolution trait dissection in melon ( <i>Cucumis melo</i> ) Open
SUMMARY Linking genotype with phenotype is a fundamental goal in biology and requires robust data for both. Recent advances in plant‐genome sequencing have expedited comparisons among multiple‐related individuals. The abundance of structur…
View article: Melon pan-genome and multi-parental framework for highresolution trait dissection
Melon pan-genome and multi-parental framework for highresolution trait dissection Open
Gff3 annotation files for 25 de-novo melon genomes discussed in publication. These are draft annotations based on lif-over from "Harukei-3" and "HS" melon genomes. Genome fasta files can be found in NCBI PRJNA726743
View article: Melon pan-genome and multi-parental framework for highresolution trait dissection
Melon pan-genome and multi-parental framework for highresolution trait dissection Open
Gff3 annotation files for 25 de-novo melon genomes discussed in publication. These are draft annotations based on lif-over from "Harukei-3" and "HS" melon genomes. Genome fasta files can be found in NCBI PRJNA726743
View article: Melon pan-genome and multi-parental framework for high-resolution trait dissection
Melon pan-genome and multi-parental framework for high-resolution trait dissection Open
Linking between genotype and phenotype is a fundamental goal in biology and requires robust data for both layers. The prominent increase in plant genome sequencing and comparisons of multiple related individuals, exposed the abundance of s…
View article: Practice Variation Research in Degenerative Lumbar Disc Surgery: A Literature Review on Design Characteristics and Outcomes
Practice Variation Research in Degenerative Lumbar Disc Surgery: A Literature Review on Design Characteristics and Outcomes Open
Study Design Literature review. Objective To describe whether practice variation studies on surgery in patients with lumbar degenerative disc disease used adequate study methodology to identify unwarranted variation, and to inform quality …
View article: Underground Heterosis for Melons Yield
Underground Heterosis for Melons Yield Open
Heterosis, the superiority of hybrids over their parents, is a major genetic force associated with plant fitness and crop yield enhancement. Understanding and predicting heterosis is crucial for evolutionary biology, as well as for plant a…
View article: Peer Review #1 of "Heavier- and lighter-load isolated lumbar extension resistance training produce similar strength increases, but different perceptual responses, in healthy males and females (v0.1)"
Peer Review #1 of "Heavier- and lighter-load isolated lumbar extension resistance training produce similar strength increases, but different perceptual responses, in healthy males and females (v0.1)" Open
Objectives: Muscles dominant in type I muscle fibres, such as the lumbar extensors, are often trained using lighter loads and higher repetition ranges.However, literature suggests that similar strength adaptations can be attained by the us…
View article: Peer Review #1 of "Heavier- and lighter-load isolated lumbar extension resistance training produce similar strength increases, but different perceptual responses, in healthy males and females (v0.2)"
Peer Review #1 of "Heavier- and lighter-load isolated lumbar extension resistance training produce similar strength increases, but different perceptual responses, in healthy males and females (v0.2)" Open
Objectives: Muscles dominant in type I muscle fibres, such as the lumbar extensors, are often trained using lighter loads and higher repetition ranges.However, literature suggests that similar strength adaptations can be attained by the us…