Imad Uddin
YOU?
Author Swipe
View article: SYNTHESIS AND CHARACTERIZATION OF IRON OXIDE NANO PARTICLES FOR TARGETED THERAPY
SYNTHESIS AND CHARACTERIZATION OF IRON OXIDE NANO PARTICLES FOR TARGETED THERAPY Open
Iron oxide nanoparticles represent a promising platform for targeted cancer therapy due to their unique magnetic properties, biocompatibility, and potential for surface functionalization. This study synthesized IONPs via the co-precipitati…
View article: A promising α-glucosidase and α-amylase inhibitors based on benzimidazole-oxadiazole hybrid analogues: Evidence based in vitro and in silico studies
A promising α-glucosidase and α-amylase inhibitors based on benzimidazole-oxadiazole hybrid analogues: Evidence based in vitro and in silico studies Open
The present study reports the design and synthesis of new benzimidazole-oxadiazole compounds as potent inhibitors of α-glucosidase and α-amylase. The synthesized molecules were characterized through different techniques such as 1HNMR, 13CN…
View article: Identification of Disalicyloyl Curcumin as a Potential DNA Polymerase Inhibitor for Marek’s Disease Herpesvirus: A Computational Study Using Virtual Screening and Molecular Dynamics Simulations
Identification of Disalicyloyl Curcumin as a Potential DNA Polymerase Inhibitor for Marek’s Disease Herpesvirus: A Computational Study Using Virtual Screening and Molecular Dynamics Simulations Open
Marek’s disease virus (MDV) is a highly contagious and persistent virus that causes T-lymphoma in chickens, posing a significant threat to the poultry industry despite the availability of vaccines. The emergence of new virulent strains has…
View article: Contrast Induce Nephropathy in Patients Undergoing Percutaneous Coronary Intervention for Acute Coronary Syndrome: Differences in STEMI and NSTEMI
Contrast Induce Nephropathy in Patients Undergoing Percutaneous Coronary Intervention for Acute Coronary Syndrome: Differences in STEMI and NSTEMI Open
Contrast-induced nephropathy (CIN) is a common complication of percutaneous coronary intervention (PCI) in patients with acute coronary syndrome. The incidence and risk factors for CIN in patients with ST-segment elevation myocardial infar…
View article: Clinical Outcomes of Unprotected Left Main Stem Stenting: An Observational Single-Centre Study
Clinical Outcomes of Unprotected Left Main Stem Stenting: An Observational Single-Centre Study Open
Objectives: To know the clinical outcomes of percutaneous intervention (PCI) with drug eluting stents (DES) in patients with unprotected left main stem disease. Materials and Methods: This single-centre, prospective, observational study wa…
View article: Predilation Ballooning in High Thrombus Laden STEMIs: An Independent Predictor of Slow Flow in Patients Undergoing Emergent Percutaneous Coronary Revascularization
Predilation Ballooning in High Thrombus Laden STEMIs: An Independent Predictor of Slow Flow in Patients Undergoing Emergent Percutaneous Coronary Revascularization Open
Introduction: Predilation ballooning in high thrombus-laden ST-elevation myocardial infarctions (STEMIs) is a technique used during emergent percutaneous coronary revascularization (PCI) to improve blood flow and reduce clot burden in the …
View article: Association of Radial Artery Access with Reduced Incidence of Acute Kidney Injury
Association of Radial Artery Access with Reduced Incidence of Acute Kidney Injury Open
Introduction: Acute kidney injury (AKI) is a common complication that can occur after invasive cardiac procedures. This condition can cause significant morbidity and mortality, especially in high-risk patients, such as those with preexisti…
View article: Synthesis and Characterization of Ni Nanoparticles via the Microemulsion Technique and Its Applications for Energy Storage Devices
Synthesis and Characterization of Ni Nanoparticles via the Microemulsion Technique and Its Applications for Energy Storage Devices Open
Herein, a unique synthetic approach called microemulsion is used to create nickel nanoparticles (Ni-NPs). SEM, TEM, EDX, and XRD techniques were employed for the investigation of morphology and structures of the synthesized material. Elect…
View article: Comparative outcomes of MACE after Drug eluting balloon Vs. Drug Eluting Stent in treatment of in-stent restenosis (ISR) patients presented with acute coronary syndrome.
Comparative outcomes of MACE after Drug eluting balloon Vs. Drug Eluting Stent in treatment of in-stent restenosis (ISR) patients presented with acute coronary syndrome. Open
Background: Currently, patients with coronary artery disease are advised to use coronary stenting as their primary revascularization method. This study aims to compare outcome of MACE after DEB Vs DES in treatment of patients within stent …
View article: Investigation on Crystal-Structure, Thermal and Electrical Properties of PVDF Nanocomposites with Cobalt Oxide and Functionalized Multi-Wall-Carbon-Nanotubes
Investigation on Crystal-Structure, Thermal and Electrical Properties of PVDF Nanocomposites with Cobalt Oxide and Functionalized Multi-Wall-Carbon-Nanotubes Open
Nanocomposites of polyvinylidene fluoride (PVDF) with dimensional (1D) cobalt oxide (Co3O4) and f-MWCNTs were prepared successfully by the solution casting method. The impact of 1D Co3O4 filler and 1D Co3O4/f-MWCNTs co-fillers on the struc…
View article: Intracellular Activation of Anticancer Therapeutics Using Polymeric Bioorthogonal Nanocatalysts
Intracellular Activation of Anticancer Therapeutics Using Polymeric Bioorthogonal Nanocatalysts Open
Bioorthogonal catalysis provides a promising strategy for imaging and therapeutic applications, providing controlled in situ activation of pro‐dyes and prodrugs. In this work, the use of a polymeric scaffold to encapsulate transition metal…
View article: Intracellular Activation of Bioorthogonal Nanozymes through Endosomal Proteolysis of the Protein Corona
Intracellular Activation of Bioorthogonal Nanozymes through Endosomal Proteolysis of the Protein Corona Open
Bioorthogonal activation of prodrugs provides a strategy for on-demand on-site production of therapeutics. Intracellular activation provides a strategy to localize therapeutics, potentially minimizing off-target effects. To this end, nanop…
View article: Synthetic Biscoumarin Analogs: Their PC3 Cell Line and Antioxidant Inhibitory Potentials
Synthetic Biscoumarin Analogs: Their PC3 Cell Line and Antioxidant Inhibitory Potentials Open
Prostate cancer is perhaps the most dominant cancer in men. The increased resistance to therapeutic agents and deficiency of targeted therapy for prostate cancer cells offer motivation to find new scaffolds for the treatment. The current s…
View article: Synthesis and Molecular Docking Study of bis-thiobarbiturate Derivatives as Effective Inhibitors of beta-glucuronidase
Synthesis and Molecular Docking Study of bis-thiobarbiturate Derivatives as Effective Inhibitors of beta-glucuronidase Open
Bis-thiobarbiturate derivatives 1-15 have been synthesized and evaluated for their in vitro β-glucuronidase inhibitory potential. The structures of all compounds were confirmed through spectroscopic techniques such as EI-MS and 1HNMR. Comp…
View article: Tannic Acid Based Gold Nanosensor for Selective Detection of Hg+2 and Pefloxacine
Tannic Acid Based Gold Nanosensor for Selective Detection of Hg+2 and Pefloxacine Open
Tannic acid capped gold nanoparticles with a mean diameter of 20nm were efficiently prepared by the green synthetic route. The size and morphology of gold nanoparticles were investigated by transmission electron microscopy and atomic force…
View article: Synthesis, anti-leishmanial and molecular docking study of bis-indole derivatives
Synthesis, anti-leishmanial and molecular docking study of bis-indole derivatives Open
We have synthesized new series of bisindole analogs (1-27), characterized by 1HNMR and HR-EI-MS and evaluated for their anti-leishmanial potential. All compounds showed outstanding inhibitory potential with IC50 values ranging from 0.7 ± 0…
View article: Hepato-Protective Studies of Poloxamer-188 by Paracetomol induced liver toxicity in Rats
Hepato-Protective Studies of Poloxamer-188 by Paracetomol induced liver toxicity in Rats Open
Poloxamer-188 (P-188) is a polymer well renowned for possessing medical properties. Present study was conducted with an aim to evaluate Hepato-protective potential of P-188 against paracetamol induced liver damage in wistar albino rats. Gr…
View article: Modulating the catalytic activity of enzyme-like nanoparticles through their surface functionalization
Modulating the catalytic activity of enzyme-like nanoparticles through their surface functionalization Open
Surface functional groups of nanozyme ligands dictate their kinetic behavior.