Imam Mustofa
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View article: Redox Signaling as A Double-Edged Regulator: Bridging Molecular Mechanisms, Physiological Balance, Pathological Disruption, and Emerging Precision Therapies in Human Health and Disease
Redox Signaling as A Double-Edged Regulator: Bridging Molecular Mechanisms, Physiological Balance, Pathological Disruption, and Emerging Precision Therapies in Human Health and Disease Open
Redox signaling has emerged as a key mechanism linking cellular metabolism with systemic physiology through controlled fluctuations of reactive oxygen and nitrogen species (ROS/RNS). Once considered merely harmful byproducts, ROS and RNS a…
View article: Revolutionizing curcumin bioavailability: From health benefits to placement in food packaging products
Revolutionizing curcumin bioavailability: From health benefits to placement in food packaging products Open
Curcumin, the principal bioactive compound in turmeric ( Curcuma longa L. ), is widely recognized for its pharmacological properties, including antioxidant, anti-inflammatory, and anticancer activities. However, its low bioavailability rem…
View article: Zinc in Human Health: A Comprehensive Review of its Biological Roles and Clinical Implications
Zinc in Human Health: A Comprehensive Review of its Biological Roles and Clinical Implications Open
Zinc (Zn) is an essential micronutrient involved in enzymatic activity, protein and membrane structure, gene regulation, and immune and antioxidant functions. Both excess and deficiency influence health, affecting reproduction, skin, bones…
View article: Penerapan Green Roof Dengan Integrasi Lean Construction Pada Bangunan Gedung Pelayanan Publik Kabupaten Kediri
Penerapan Green Roof Dengan Integrasi Lean Construction Pada Bangunan Gedung Pelayanan Publik Kabupaten Kediri Open
Penelitian ini menganalisis penerapan green roof yang diintegrasikan dengan lean construction pada Gedung Pelayanan Publik Kabupaten Kediri, dengan fokus pada efisiensi konstruksi dan dampak lingkungan. Green roof dipilih sebagai solusi in…
View article: Silicon Dioxide in Active Food Packaging: A Review on Mesoporous Carriers for Encapsulated Antioxidants and Antimicrobials
Silicon Dioxide in Active Food Packaging: A Review on Mesoporous Carriers for Encapsulated Antioxidants and Antimicrobials Open
The increasing demand for packaging technologies that actively maintain food quality and safety has highlighted the potential of silicon dioxide (SiO₂) as a multifunctional material. This review discusses the physicochemical properties, me…
View article: Oxidative Stress: Molecular Mechanisms, Role in Pathology, and Therapeutic Implications
Oxidative Stress: Molecular Mechanisms, Role in Pathology, and Therapeutic Implications Open
Oxidative stress is a biological state caused by an imbalance between the generation of reactive oxygen species (ROS) and the antioxidant system’s capacity to maintain redox homeostasis. This imbalance can damage vital biomolecules, includ…
View article: Impact of Various Exogenous Gonadotropins and Their Combination on the Enhancement of Conception Rate in Equines
Impact of Various Exogenous Gonadotropins and Their Combination on the Enhancement of Conception Rate in Equines Open
Background: Mares are seasonal breeders, active in spring and summer when daylight is longer, ensuring foals are born in spring for ideal conditions. Having more foals in a breeding season is desirable for stud owners to improve their econ…
View article: Epigallocatechin-3-gallate chitosan nanoparticles in an extender improve the antioxidant capacity and post-thawed quality of Kacang goat semen
Epigallocatechin-3-gallate chitosan nanoparticles in an extender improve the antioxidant capacity and post-thawed quality of Kacang goat semen Open
Background and Aim The Kacang goat (Capra hircus) is an indigenous livestock species in Indonesia that is at risk of extinction due to cross-breeding. Artificial insemination (AI) techniques are expected to increase the population of these…
View article: Integrating morphometrics and seminal plasma metabolomics to predict fertility in Yoruba Ecotype × Sussex crossbred cocks
Integrating morphometrics and seminal plasma metabolomics to predict fertility in Yoruba Ecotype × Sussex crossbred cocks Open
Background and Aim: Enhancing poultry reproductive performance is essential for improving productivity and addressing protein shortages in developing regions. Yoruba ecotype chickens (YECs) are resilient but limited in commercial potential…
View article: Unlocking the Power of Capsaicin: A Comprehensive Review of Its Mechanisms and Applications
Unlocking the Power of Capsaicin: A Comprehensive Review of Its Mechanisms and Applications Open
Capsaicin is the main bioactive compound in chili peppers (Capsicum sp.) that has attracted widespread attention in pharmacology and health. This substance functions by stimulating the Transient Receptor Potential Vanilloid 1 (TRPV1) recep…
View article: SOSIALISASI PENERAPAN TEKNOLOGI BIM SEBAGAI SOLUSI EFISIENSI MATERIAL TULANGAN DI TULUNGAGUNG
SOSIALISASI PENERAPAN TEKNOLOGI BIM SEBAGAI SOLUSI EFISIENSI MATERIAL TULANGAN DI TULUNGAGUNG Open
Transformasi digital dalam industri konstruksi menuntut peningkatan efisiensi dan akurasi, terutama dalam pengelolaan material seperti besi tulangan yang memiliki kontribusi besar terhadap struktur dan biaya proyek. Building Information Mo…
View article: Additive Nutrition in the Feeding of Pote Goat Madura Maintained the Fertility Post-Infected of Foot and Mouth Disease
Additive Nutrition in the Feeding of Pote Goat Madura Maintained the Fertility Post-Infected of Foot and Mouth Disease Open
Mineral and nutritive supplements improve animal reproductive performance, especially after Foot and Mouth Disease (FMD) infecteds, to establish sustainable food security solutions. This study aimed to investigate the effects of mineral ad…
View article: THE EFFECT OF BREED AND BODY CONDITION SCORE ON OVARIAN WEIGHT, NUMBER OF FOLLICLES, AND OOCYTE QUALITY IN RETIRED COWS
THE EFFECT OF BREED AND BODY CONDITION SCORE ON OVARIAN WEIGHT, NUMBER OF FOLLICLES, AND OOCYTE QUALITY IN RETIRED COWS Open
The aim of this study was to determine whether breed and body condition score (BCS) can influence ovarian weight, follicle number, and oocyte quality. This study used 90 ovaries from 15 Friesian Holstein crossbreed, 15 Ongole crossbreed, a…
View article: Strategic approaches to improve equine breeding and stud farm outcomes
Strategic approaches to improve equine breeding and stud farm outcomes Open
This review explores advanced strategies for enhancing fertility and optimizing reproductive outcomes in equine breeding programs. Horses, being seasonal breeders, present unique reproductive challenges influenced by environmental and phys…
View article: Effect of nanocurcumin (Curcuma longa) on lung histopathology in rats exposed to carbon black
Effect of nanocurcumin (Curcuma longa) on lung histopathology in rats exposed to carbon black Open
Background Exposure to carbon black can induce respiratory toxicity, leading to tissue remodeling, inflammation, and fibrosis. Curcumin, a compound from Curcuma longa, has been shown to exert protective effects on lung tissue by inhibiting…
View article: <b>Impact of Moringa oleifera leaf extract on renal histopathology, malondialdehyde, superoxide dismutase, and calcium oxalate crystals in rats (<i>Rattus norvegicus</i>) exposed to ethylene glycol</b>
<b>Impact of Moringa oleifera leaf extract on renal histopathology, malondialdehyde, superoxide dismutase, and calcium oxalate crystals in rats (<i>Rattus norvegicus</i>) exposed to ethylene glycol</b> Open
Background: Nephrolithiasis is a kidney disorder caused by the formation of crystals through physiological and chemical processes in the body, with calcium oxalate being a major contributor. Moringa oleifera leaves are known for their anti…
View article: <b>Restoration of sperm quality in lead acetate-induced rats via treatment with <i>Moringa oleifera</i> leaf extract</b>
<b>Restoration of sperm quality in lead acetate-induced rats via treatment with <i>Moringa oleifera</i> leaf extract</b> Open
Background: Lead intoxication triggers testicular toxicity via oxidative stress. Aim: This study aimed to explore the antioxidant potential of Moringa oleifera leaf extract (MOLE) in enhancing the semen quality of rats exposed to lead acet…
View article: <b>Marek’s disease: A global challenge to poultry health and productivity</b>
<b>Marek’s disease: A global challenge to poultry health and productivity</b> Open
Marek’s disease is a neuropathic and lymphoproliferative viral condition that primarily affects chickens and occasionally affects quail and turkeys. It is caused by the Marek’s disease virus (MDV), a member of the family Herpesviridae, sub…
View article: <b>Potential of microbial-based feed additives on broiler carcass and fat percentages</b>
<b>Potential of microbial-based feed additives on broiler carcass and fat percentages</b> Open
Background: Factors before and after slaughter can influence carcass quality. A factor that can affect carcass quality before slaughter is feed that includes additives. One alternative is to administer probiotics. Aim: This study aimed to …
View article: <b>The global burden of swine influenza and its mitigation</b>
<b>The global burden of swine influenza and its mitigation</b> Open
Swine influenza, often known as swine flu, is a respiratory disease caused by type A influenza virus (IAV) called swine influenza virus (SIV). There are currently multiple subtypes of IAV in pigs, including H1N1, H1N2, and H3N2. While the …
View article: The percentage of concentrate intake, daily milk yield, serum IGF-1, and estrogen level of small holders dairy cows based on blood urea nitrogen and pregnancy status
The percentage of concentrate intake, daily milk yield, serum IGF-1, and estrogen level of small holders dairy cows based on blood urea nitrogen and pregnancy status Open
Background: The small holders dairy farming is the largest fresh milk producer in Indonesia. Reproduction depends on dietary proteins, and raised blood or milk urea, increased dietary crude proteins, and increased dietary protein degradabi…
View article: <b>Review of neosporosis: Disease insights and control approaches</b>
<b>Review of neosporosis: Disease insights and control approaches</b> Open
The protozoan parasite Neospora caninum is the cause of the infectious disease neosporosis. N. caninum is now a major parasite that affects dogs and livestock all over the world. Cattle abortions are now most frequently caused by neosporos…
View article: <b>Protective effect of epigallocatechin-gallate in cryopreserved goat sperm on post-thawed quality</b>
<b>Protective effect of epigallocatechin-gallate in cryopreserved goat sperm on post-thawed quality</b> Open
Background: Cryopreservation is a useful technique for preserving goat sperm, but it often causes damage due to oxidative stress triggered by increased reactive oxygen species (ROS). One promising solution is the use of antioxidants, such …
View article: Improved Litter Size in Thin‐Tailed Indonesian Sheep Through Analysis of TGIF1 Gene Polymorphisms
Improved Litter Size in Thin‐Tailed Indonesian Sheep Through Analysis of TGIF1 Gene Polymorphisms Open
Reproductive traits, particularly the litter size, are crucial for sheep husbandry. Molecular genetic selection methods, including single‐nucleotide polymorphism (SNP) analyses, offer potential avenues for enhancing these traits. This stud…
View article: <b>Hidden menace: Understanding the devastating consequences of dourine disease in horses</b>
<b>Hidden menace: Understanding the devastating consequences of dourine disease in horses</b> Open
Trypanosoma equiperdum is a protozoan parasite that causes the sexually transmitted disease known as "dourine" in horses. This chronic illness is spread directly from one animal to another during mating. Doflein proposed the name T. equipe…
View article: <b>Potential of growth factors and steroid hormones from cell cultures to improve <i>in vitro</i> fertilization in bovine</b><b></b>
<b>Potential of growth factors and steroid hormones from cell cultures to improve <i>in vitro</i> fertilization in bovine</b><b></b> Open
The application of biotechnology is an attempt to improve animal reproduction efficiency, specifically to produce cattle of high quality and quantity. One method that is seen to be successful and efficient in the field of reproduction is e…
View article: <b>The role of heat shock protein 70 on oocyte apoptosis during vitrification</b>
<b>The role of heat shock protein 70 on oocyte apoptosis during vitrification</b> Open
The cryopreservation of animal and human oocytes has potential for the development of Assisted Reproductive Technology (ART), especially as bank of oocytes. One of the techniques used for oocyte cryopreservation is vitrification procedure …
View article: <b>Glanders: Historical military use and potential bioterrorism concern</b>
<b>Glanders: Historical military use and potential bioterrorism concern</b> Open
Burkholderia mallei, the etiological agent of glanders, is a zoonotic bacterium primarily affecting equines and occasionally humans. Although rare today, it remains endemic in certain regions and poses a potential threat to both animal and…
View article: <b>Effect of fermented red bean extract (<i>Phaseolus vulgaris</i> L.) on spermatogenic cells in mice exposed to smoke</b>
<b>Effect of fermented red bean extract (<i>Phaseolus vulgaris</i> L.) on spermatogenic cells in mice exposed to smoke</b> Open
Background: Red beans are known to be rich in bioactive compounds such as flavonoids, anthocyanins, tannins, and polyphenols that have high antioxidant activity so that they are believed to be able to provide protection against testicular …
View article: <b><i>In silico</i> study: Hepatoprotective effects of capsaicin on the liver of aflatoxin B1-intoxicated mice (<i>Mus musculus</i>)</b>
<b><i>In silico</i> study: Hepatoprotective effects of capsaicin on the liver of aflatoxin B1-intoxicated mice (<i>Mus musculus</i>)</b> Open
Background: Mycotoxins are secondary metabolites produced by fungi that cause serious diseases and death. Among the mycotoxins, aflatoxins stand out for their significant toxic impact, especially Aflatoxin B1 (AFB1) produced by Aspergillus…