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A young adult patient with Philadelphia positive acute lymphoblastic leukemia presenting with extreme hyperleukocytosis Open
Key Clinical Message Extreme hyperleukocytosis (Leukocyte count >200 × 10 9 /L) in an adolescent young adult (AYA) patient with B‐ALL could result in mild symptoms of leukostasis. Hyperleukocytosis requires prompt initiation of therapy wit…
Effectiveness and safety of therapeutic plasma exchange in neurological diseases: An 11‐year report from a tertiary care center Open
Background Therapeutic plasma exchange has been a well‐known treatment method for many years and is widely available. It leads to the improvement of neurological symptoms in autoimmune neurological diseases by the removal of antibodies. Th…
Oral iron absorption test: myth or reality? Open
Introduction: Anemia is a serious health problem affecting one-third of the world's population. The most common etiology is iron deficiency anemia (IDA). The oral iron absorption test (OIAT) is a method that has been used for a long time t…
Prognostic Value of the Expression of Receptor Tyrosine Kinase-Like Orphan Receptor 1 (ROR-1) in Chronic Lymphocytic Leukemia Open
Background: The transmembrane receptor tyrosine kinase-like orphan receptor 1 (ROR1) has acted on the causation and sustentation of mature B cell lymphomagenesis for chronic lymphocytic leukemia (CLL) cells. The aim of this study was to sh…
View article: Outcomes of COVID-19 Patients Undergoing Therapeutic Plasma Exchange in Intensive Care Units
Outcomes of COVID-19 Patients Undergoing Therapeutic Plasma Exchange in Intensive Care Units Open
Aim:The place of therapeutic plasma exchange in severe COVID-19 patients is a controversial issue.Data on the relationship between the clinical variables and dynamics of inflammatory markers and outcomes are limited.In this study, we aimed…
A Giant Mass in the Eyelid: Peripheral T-Cell Lymphoma, Not Otherwise Specified Open
Purpose: To report a case with an unusual giant mass in the eyelid which was diagnosed as peripheral T-cell lymphoma, not otherwise specified (PTCL-NOS). Methods: A 40-year-old woman was referred with a 1-year history of rapidly and consta…
Leukemia: Reduction Ratio and Halving Time of BCR: : ABL1 IS Transcript Levels Open
Objective: Achieving an early molecular response (EMR) is crucial for improving the prognosis of patients with chronic myeloid leukemia (CML). The halving time (HT) and reduction ratio (RR) of BCR: : ABL1 transcript levels have recently em…
Predictive Factors for Molecular Response in Chronic Myeloid Leukemia: Reduction Ratio and Halving time of BCR: : ABL1 IS Transcript Levels Open
Our findings revealed that MMR could be predicted via EMR as well as by HT and RR. Additionally, HT of ≤24 days and RR of ≤0.04 were more important than BCR::ABL1 IS of ≤10% in achieving DMR at 24 months, and the combination of BCR::ABL1 I…
Evaluation of Bone Mineral Densitometry Measurements in Patients with BCR/ABL-Negative Chronic Myeloproliferative Neoplasm Open
Introduction: This study aims to determine the changes in and the factors related to the bone mineral density in patients with bcr/abl-negative chronic myeloproliferative neoplasm (cmpd).Methods: The data of 38 males (52.1%) and 35 females…
VAD Chemotherapy Versus Bortezomib Containing Regimens As Remission Induction For ASCT in Multiple Myeloma: A Single Center Experience Open
Background: Complete response (CR) and very good partial response (VGPR) are targeted with pre-ASCT induction regimens in patients by diagnosed multiple myeloma (MM), who are candidates for ASCT. In this study, it was aimed to compare the …
Transfusion in autoimmune hemolytic anemia: comparison of two different strategies Open
Objective: Autoimmune Hemolytic Anaemia (AIHA) is a condition in which red blood cells (RBC) are destroyed by autoantibodies. Clinicians tend to avoid the transfusion in AIHA patients who has difficulties during pre-transfusional testing. …
Vitamin D Deficiency and Janus kinase 2 V617F Mutation Status in Essential Thrombocythemia and Polycythemia Vera Open
There was a remarkably higher prevalence of vitamin D deficiency in JAK2 mutation-positive ET and PV patients. These patients should be carefully evaluated for vitamin D deficiency. More studies are required to further investigate the asso…
Does the platelet‑to‑lymphocyte ratio have a prognostic effect in patients with myelodysplastic syndrome? Open
INTRODUCTION: Myelodysplastic syndromes (MDS) include various hematologic abnormalities characterized by chronic cytopenia due to disruption in cellular differentiation.This study aims to evaluate the prognostic value of PLR in patients wi…
PB2013 LACTATE DEHYDROGENASE LEVEL IS ASSOCIATED WITH A WORSE OUTCOME IN TURKISH PATIENTS WITH HAIRY CELL LEUKEMIA Open
Background: Hairy cell leukemia (HCL) is a rare B‐cell lymphoproliferative disorder. It manifests with cytopenia, hepatosplenomegaly, recurrent infections and constitutional symptoms due to the accumulation of malignant cells in hematopoet…
PB1886 THE TRANSMEMBRANE RECEPTOR TYROSINE KINASE‐LIKE ORPHAN RECEPTOR 1 IN CHRONIC LYMPHOCYTIC LEUKEMIA Open
Background: B‐cell chronic lymphocytic leukemia (CLL) is the most common haematological malignancy in advanced age. The clinical course of the disease is highly variable, therefore there is a need to investigate the various prognostic fact…
PB2171 THE COMPARISON OF THE RELATIONSHIP BETWEEN POLYNEUROPATHY FREQUENCY AND CLINICAL AND LABORATORY FINDINGS IN MULTIPLE MYELOMA CASES Open
Background: Multiple myeloma (MM) patients compose approximately 10% of patients with hematological malignancies. Polyneuropathy (PN) is one of the most important complications related to the disease and treatment. Aims: Multiple myeloma (…
Thiol-disulphide homeostasis in essential thrombocythemia patients Open
Summary Background This study aimed to show the status of thioldisulphide homeostasis in essential thrombocytosis patients, which is known to play a role in platelet function. Methods The study included 27 ET patients and a control group o…
AUER RODS IN MATURE NEUTROPHILS IN A CASE OF ACUTE PROMYELOCYTIC LEUKEMIA Open
Acute promyelocytic leukemia is characterized by the presence of atypical promyelocytes in bone marrow and peripheral blood. Neoplastic promyelocytes, which often have Auer rods, are most commonly seen in early myeloid precursors in certai…
The least incompatible crossmatch red blood cell transfusion by biological compatibility test Open
Introduction: Pretransfusion testing is an essential serological test to protect the recipient from hemolysis and provide compatible blood product. The final step is the crossmatching test which is done by the transfusion center. Although …
Frequency of ASFA 3 Category Therapeutic Plasmapheresis in Reanimation Intensive Care Units Open
ÖZET GİRİŞ ve AMAÇ: Teröpotik plazma değişimi (TPD) hasta plazmasının büyük kısmının replasman sıvılarıyla değiştirilip hastaya geri verildiği bir işlemdir.TPD işlemi hematolojik, romatolojik, nörolojik ve toksikolojik hastalıklar olmak üz…
Development of plasma cell leukemia in a patient with chronic myeloid leukemia while on treatment with imatinib mesylate Open
Plasma cell leukemia (PCL) is a rare and an aggressive form of plasma cell dyscrasias. We report a 67-year-old male with PCL which developed while on imatinib mesylate (IM) therapy 38 months after diagnosis of chronic myeloid leukemia (CML…
Prevalence and current management of perianal diseases in patients with acute leukemia Open
Aim: Perianalinfection is one of the most important causes of infection in acute leukemiawhich puts the life of patients at risk, increases their morbidity and impairsquality of life.Material and Method: Atthe Ankara Atatürk Training and R…
Unexpected Adverse Effect of Clofarabın Plus Cytosıne Arabınosıde: Bronze Hyperpıgmentatıon Open
The combination of the words “therapy†and “diagnostics†have been purposed as a platform that combines some specific diagnostic with specific therapy, based on the results from the diagnostic. It is a step towards personalized medic…
Importance of vitamin d level in early-stage chronic lymphocytic leukemia and its comparison with healthy population Open
Chronic lymphocytic leukemia (CLL) is a chronic lymphoproliferative hematological malignancy accompanied by a Chronic lymphocytic leukemia (CLL) is a chronic lymphoproliferative hematological malignancy accompanied by a monoclonal prolifer…