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View article: Integrated Network Pharmacology and Molecular Dynamics Reveal Multi-Target Anticancer Mechanisms of Myrtus communis Essential Oils
Integrated Network Pharmacology and Molecular Dynamics Reveal Multi-Target Anticancer Mechanisms of Myrtus communis Essential Oils Open
Background: Cancer’s multifactorial complexity demands innovative polypharmacological strategies that can simultaneously target multiple oncogenic pathways. Natural products, with their inherent chemical diversity, offer promising multi-ta…
View article: Substitution-induced changes in the structure, vibrational, and magnetic properties of BiFeO<sub>3</sub>
Substitution-induced changes in the structure, vibrational, and magnetic properties of BiFeO<sub>3</sub> Open
To address practical progress and prospective applications of BiFeO 3 , we substituted it with the perovskite BaTi 0.9 Zr 0.1 O 3 to form the system (1 − x )BiFeO 3 -( x )BaTi 0.9 Zr 0.1 O 3 , limiting x to the range of 0–0.4.
View article: Role of biochar in anaerobic microbiome enrichment and methane production enhancement during olive mill wastewater biomethanization
Role of biochar in anaerobic microbiome enrichment and methane production enhancement during olive mill wastewater biomethanization Open
The current research work attempted to investigate, for the first time, the impact of biochar addition, on anaerobic digestion of olive mill wastewater with different initial chemical oxygen demand loads in batch cultures (10 g/L, 15 g/L, …
View article: Intensification of Biophenols Extraction Yield from Olive Pomace Using Innovative Green Technologies
Intensification of Biophenols Extraction Yield from Olive Pomace Using Innovative Green Technologies Open
Olive pomace is the main by-product generated by the olive oil production process. Although toxic to the environment, olive pomace is an important source of natural antioxidants due to its high content of phenolic compounds. The aim of the…
View article: Punica granatum Peel and Leaf Extracts as Promising Strategies for HSV-1 Treatment
Punica granatum Peel and Leaf Extracts as Promising Strategies for HSV-1 Treatment Open
Punica granatum is a rich source of bioactive compounds which exhibit various biological effects. In this study, pomegranate peel and leaf ethanolic crude extracts (PPE and PLE, respectively) were phytochemically characterized and screened…
View article: Modeling of antiproliferative effects of Salvia officinalis L. essential oil optimized using Box–Behnken design
Modeling of antiproliferative effects of Salvia officinalis L. essential oil optimized using Box–Behnken design Open
The objectives of this work were to optimize hydro-distillation extraction of Salvia officinalis L. essential oil (SoEO) and to evaluate the in vitro scavenging capacity of the free radicals DPPH·, NO·, ABTS+, and the ability to reduce Fe3…
View article: In Vitro Anti-Epstein Barr Virus Activity of Olea europaea L. Leaf Extracts
In Vitro Anti-Epstein Barr Virus Activity of Olea europaea L. Leaf Extracts Open
Olea europaea L. var. sativa (OESA) preparations are widely used in traditional medicine in the Mediterranean region to prevent and treat different diseases. In this research, olive extracts derived from the leaves of the OESA tree have be…
View article: Modeling of antiproliferative effects of Salvia officinalis L. essential oil optimized using Box–Behnken design
Modeling of antiproliferative effects of Salvia officinalis L. essential oil optimized using Box–Behnken design Open
Background Salvia officinalis L. essential oil (SoEO) was mostly traditionally used to medicate various diseases as cancer. Then, the present work aims were: (1) to model the cytotoxicity effects of Salvia officinalis L. essential oil (SoE…
View article: Antimicrobial, antioxidant and anti-EBV activities of olive leaf (Olea Europea) extracts from Tunisia
Antimicrobial, antioxidant and anti-EBV activities of olive leaf (Olea Europea) extracts from Tunisia Open
The authors have withdrawn this preprint from Research Square
View article: Antimicrobial, antioxidant and anti-EBV activities of olive leaf (Olea Europea) extracts from Tunisia
Antimicrobial, antioxidant and anti-EBV activities of olive leaf (Olea Europea) extracts from Tunisia Open
Background: Olive tree leaves ( Olea europaea ) are widely used in traditional medicine in the Mediterranean Region. Interest in the olive leaf and its chemical constituents has recently been increasing. Its benefits, however, have been kn…
View article: Optimization of Cinnamon (<i>Cinnamomum zeylanicum</i> Blume) Essential Oil Extraction: Evaluation of Antioxidant and Antiproliferative Effects
Optimization of Cinnamon (<i>Cinnamomum zeylanicum</i> Blume) Essential Oil Extraction: Evaluation of Antioxidant and Antiproliferative Effects Open
Having high cytotoxicity cell line effect, Cinnamomum zeylanicum Blume essential oil offers a novel approach to the chemotherapy treatment. In order to enhance its quantity/purity, the experimental conditions to produce essential oil shoul…
View article: 4CPS-046 Glucocorticoids in chronic inflammatory diseases: assessment of patients’ adherence
4CPS-046 Glucocorticoids in chronic inflammatory diseases: assessment of patients’ adherence Open
Background Glucocorticoids (GC) are widely used in the management of chronic inflammatory diseases. However, lack of patients’ adherence leads to suboptimal effectiveness of GC therapy in real-life practice Purpose The aim of this study i…
View article: A fast reconstruction algorithm for geometric inverse problems using topological sensitivity analysis and Dirichlet-Neumann cost functional approach
A fast reconstruction algorithm for geometric inverse problems using topological sensitivity analysis and Dirichlet-Neumann cost functional approach Open
This paper is concerned with the detection of objects immersed in anisotropic media from boundary measurements. We propose an accurate approach based on the Kohn-Vogelius formulation and the topological sensitivity analysis method. The inv…
View article: Retrospective Study of a Cohort of Tunisian Patients with Thyroid Cancer
Retrospective Study of a Cohort of Tunisian Patients with Thyroid Cancer Open
Thyroid cancer is a complex disease where many factors influence its morbidity and mortality. Analyzing the clinic pathological parameters of this malignant disease in a series of thyroid cancer patients allows to evaluate their clinical b…
View article: Retrospective Study of a Cohort of Tunisian Patients with Thyroid Cancer
Retrospective Study of a Cohort of Tunisian Patients with Thyroid Cancer Open
Thyroid cancer is a complex disease where many factors influence its morbidity and mortality. Analyzing the clinic pathological parameters of this malignant disease in a series of thyroid cancer patients allows to evaluate their clinical b…