Explanipedia

The complex chemistry of diversity and inclusion: a 30-year synthesis Open

Stefania Impellizzeri, Imogen R. Coe · 2024

Dr. Margaret-Ann Armour’s career as a research chemist, educator, and advocate spanned more than 40 years. Much of her work took place within a disciplinary culture ignorant of the scholarship supporting organizational change towards inclu…

Characterization of equilibrative nucleoside transport of the pancreatic cancer cell line: Panc-1 Open

Sıla Appak Başköy, Amardeep Khunkhuna, Bianca Scuric, Zlatina Tarmakova, Imogen R. Coe · 2023

These results suggest that Panc-1 is a suitable preclinical cellular model for studying NAD transport properties and potential therapies in pancreatic cancer and pharmaceutical research.

Forging Paths to Enhanced Innovation Open

Imogen R. Coe, Mehrdad Hariri · 2023

Report of the Workshop for academia, education, business, industry, government and NGOs/not-for-profit hosted by Dr. Imogen R. Coe, Dean, Faculty of Science, Ryerson University & Dr. Mehrdad Hariri, President, CSPC.

Change the Numbers: Equity, Diversity, and Inclusivity in STEM | Imogen Coe | TEDxRyersonU Open

Imogen R. Coe · 2023

In her talk, Imogen Coe addresses the lack of female representation in STEM; science, technology, engineering and math. Using humour and real life examples, she encourages women (and their allies) to break barriers, challenge stereotypes a…

Advancing women in science, medicine and global health Open

Jocalyn Clark, Liz Zuccala, Ravi Verma, Imogen R. Coe · 2023

Discussion of a special themed issue introduced by Lancet Editors Jocalyn Clark and Liz Zuccala, with contributions from #LancetWomen advisory group members Ravi Verma (International Center for Research on Women, New Delhi, India)…

Rapamycin-inspired macrocycles with new target specificity Open

Zufeng Guo, Sam Y. Hong, Jingxin Wang, Shahid Rehan, Wukun Liu , et al. · 2023

Rapamycin and FK506 are macrocyclic natural products with an extraordinary mode of action, in which they form binary complexes with FK506-binding protein (FKBP) through a shared FKBP-binding domain before forming ternary complexes with the…

Women in Science: Dr. Imogen Coe Open

Sarah Boon, Imogen R. Coe · 2023

Originally from the United Kingdom, Imogen Coe can’t remember a time when she wasn’t interested in science and how the natural world works.

Oligomerization of equilibrative nucleoside transporters: a novel regulatory and functional mechanism involving PKC and PP1 Open

Natàlia Grañé-Boladeras, Declan Williams, Zlatina Tarmakova, Katarina Stevanovic, Linda A. Villani , et al. · 2023

Equilibrative nucleoside transporters (ENTs) translocate nucleosides and nucleobases across plasma membranes, as well as a variety of anti-cancer, -viral, and -parasite nucleoside analogs. They are also key members of the purinome complex …

Equity & Excellence are Mutually Conducive; A response to Ms. Wente, Globe & Mail June 10th Open

Imogen R. Coe · 2023

[p.1]: "Dear Ms Wente I read with interest your opinion piece in the June 10th issue of the G & M. The piece was, I assume, intentionally provocative. I am compelled to respond because yours is a voice of privilege, on a national platform.…

#MySTEMJob (25 stories of women in various STEM careers) Open

Imogen R. Coe · 2023

Imogen Coe, Professor of Chemistry and Biology, speaks of her career in STEM.

Dosage-controlled intracellular delivery mediated by acoustofluidics for lab on a chip applications Open

Alinaghi Salari, Sila Appak‐Baskoy, Imogen R. Coe, John Abousawan, Costin N. Antonescu , et al. · 2023

Biological research and many cell-based therapies rely on the successful delivery of cargo materials into cells. Intracellular delivery in an in vitro setting refers to a variety of physical and biochemical techniques developed fo…

Organisational best practices towards gender equality in science and medicine Open

Imogen R. Coe, Ryan E. Wiley, Linda‐Gail Bekker · 2023

In August 2018, the president of the World Bank noted that “‘Human capital’—the potential of individuals—is going to be the most important long-term investment any country can make for its people's future prosperity and quality of life”. …

Policy Change Towards Equity and Inclusion is Good for Science in Canada Open

Lesley V. Campbell, Imogen R. Coe · 2023

[para.1.]: "In 2019, the Canadian post-secondary education (PSE) sector, and particularly the research enterprise, saw the implementation of significant initiatives relating to increasing equity, diversity and inclusion (EDI) in research, …

Researchers’ Response to Canada’s Fundamental Science Review Open

James R. Woodgett, Imogen R. Coe, Mehrdad Hariri · 2023

Report produced following summit organized by Dr. Imogen R. Coe (Ryerson University), Dr. Jim Woodgett (Lunenfeld-Tanenbaum Research Institute) and Dr. Mehrdad Hariri (CSPC).

Oligomerization of equilibrative nucleoside transporters: a novel regulatory and functional mechanism involving PKC and PP1 Open

Natàlia Grañé-Boladeras, Declan Williams, Zlatina Tarmakova, Katarina Stevanovic, Linda A. Villani , et al. · 2023

Equilibrative nucleoside transporters (ENTs) translocate nucleosides and nucleobases across plasma membranes, as well as a variety of anti-cancer, -viral, and -parasite nucleoside analogs. They are also key members of the purinome complex …

The complex chemistry of diversity and inclusion: a 30-year synthesis Open

Stefania Impellizzeri, Imogen R. Coe · 2023

Dr. Margaret-Ann Armour’s career as a research chemist, educator, and advocate spanned more than 40 years. Much of her work took place within a disciplinary culture ignorant of the scholarship supporting organizational change towards inclu…

Policy Change Towards Equity and Inclusion is Good for Science in Canada Open

Lesley V. Campbell, Imogen R. Coe · 2023

[para.1.]: "In 2019, the Canadian post-secondary education (PSE) sector, and particularly the research enterprise, saw the implementation of significant initiatives relating to increasing equity, diversity and inclusion (EDI) in research, …

Change the Numbers: Equity, Diversity, and Inclusivity in STEM | Imogen Coe | TEDxRyersonU Open

Imogen R. Coe · 2023

In her talk, Imogen Coe addresses the lack of female representation in STEM; science, technology, engineering and math. Using humour and real life examples, she encourages women (and their allies) to break barriers, challenge stereotypes a…

#MySTEMJob (25 stories of women in various STEM careers) Open

Imogen R. Coe · 2023

Imogen Coe, Professor of Chemistry and Biology, speaks of her career in STEM.

Inclusion, diversity, equity, and accessibility: From organizational responsibility to leadership competency Open

Anne Mullin, Imogen R. Coe, Ryan E. Wiley, Everton Gooden, Modupe Tunde‐Byass · 2023

An awakening to systemic anti-Black racism, anti-Indigenous racism, and harmful colonial structures in the context of a pandemic has made health inequities and injustices impossible to ignore, and is driving healthcare organizations to est…

Researchers’ Response to Canada’s Fundamental Science Review Open

James R. Woodgett, Imogen R. Coe, Mehrdad Hariri · 2023

Report produced following summit organized by Dr. Imogen R. Coe (Ryerson University), Dr. Jim Woodgett (Lunenfeld-Tanenbaum Research Institute) and Dr. Mehrdad Hariri (CSPC).

Social media for social change in science Open

Samantha Z. Yammine, Christine Liu, Paige Brown Jarreau, Imogen R. Coe · 2023

Letter to the editor, 13 April 2018.

Forging Paths to Enhanced Innovation Open

Imogen R. Coe, Mehrdad Hariri · 2023

Report of the Workshop for academia, education, business, industry, government and NGOs/not-for-profit hosted by Dr. Imogen R. Coe, Dean, Faculty of Science, Ryerson University & Dr. Mehrdad Hariri, President, CSPC.

How diversity makes science work better Open

Imogen R. Coe · 2023

[p.1]: " Just over 25 years ago, the Canadian Journal of Physics published an article by Dr. Gordon Freeman, a chemistry professor, in which he asserts that “women who work outside the home contribute to the moral degeneration of their ch…

So, you want to host an inclusive and accessible conference? Open

Ana Sofia Barrows, Mahadeo A. Sukhai, Imogen R. Coe · 2023

[p.1]: "In 2017 at the Gender Summit in Montreal, Québec, Chief Science Advisor of Canada, Dr. Mona Nemer, stated the importance of promoting diversity in Science, Technology, Engineering, and Mathematics (STEM). She emphasized that “incre…

N-linked glycosylation of N48 is required for equilibrative nucleoside transporter 1 (ENT1) function Open

Alex Bicket, Imogen R. Coe · 2023

Human equilibrative nucleoside transporter 1 (hENT1) transports nucleosides and nucleoside analogue drugs across cellular membranes and is necessary for the uptake of many anti-cancer, anti-parasitic and anti-viral drugs. Previous work, an…

An ultrafast enzyme-free acoustic technique for detaching adhered cells in microchannels Open

Alinaghi Salari, Sila Appak‐Baskoy, Imogen R. Coe, Scott Tsai, Michael C. Kolios · 2023

Adherent cultured cells are widely used biological tools for a variety of biochemical and biotechnology applications, including drug screening and gene expression analysis. One critical step in culturing adherent cells is the dissociation …

N-linked glycosylation of N48 is required for equilibrative nucleoside transporter 1 (ENT1) function Open

Alex Bicket, Imogen R. Coe · 2023

Human equilibrative nucleoside transporter 1 (hENT1) transports nucleosides and nucleoside analogue drugs across cellular membranes and is necessary for the uptake of many anti-cancer, anti-parasitic and anti-viral drugs. Previous work, an…

Enacting workplace culture change for excellence in research: a gender lens Open

Eleanor R. Haine, Hilary B. Bergsieker, Imogen R. Coe, Andrea Koch-Kraft, Ève Langelier , et al. · 2023

Science and engineering research excellence can be maximized if the selection of researchers is made from 100% of the pool of human talent. This requires policies and approaches that encourage broad sections of society, including women and…

Enacting workplace culture change for excellence in research: a gender lens Open

Eleanor R. Haine, Hilary B. Bergsieker, Imogen R. Coe, Andrea Koch-Kraft, Ève Langelier , et al. · 2023

Science and engineering research excellence can be maximized if the selection of researchers is made from 100% of the pool of human talent. This requires policies and approaches that encourage broad sections of society, including women and…

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