Imran Shahid
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View article: Molecular and structural insights into dengue virus non-structural proteins from pakistani clinical isolates for the identification of novel antiviral targets
Molecular and structural insights into dengue virus non-structural proteins from pakistani clinical isolates for the identification of novel antiviral targets Open
View article: Introductory Chapter: Viral Replication and Production Are Always Phenomenal for Viral Infections
Introductory Chapter: Viral Replication and Production Are Always Phenomenal for Viral Infections Open
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View article: Synergistic effects of a carbohydrate-controlled diet and Cuminum cyminum herbal infusion on metabolic syndrome
Synergistic effects of a carbohydrate-controlled diet and Cuminum cyminum herbal infusion on metabolic syndrome Open
Background Metabolic syndrome (MetS) is a growing global health concern and a major risk factor for conditions such as diabetic nephropathy and atherosclerosis. It is marked by chronic inflammation, insulin resistance, and dyslipidemia. Di…
View article: ULTRASONOGRAPHIC COMPARISON OF UMBLICAL ARTERY AND MIDDLE CEREBRAL ARTERY DOPPLER INDICES OF OLIGOHYDROMNIOS AND NORMAL AMNIOTIC FLUID LEVELS IN PREGNANT FEMALES
ULTRASONOGRAPHIC COMPARISON OF UMBLICAL ARTERY AND MIDDLE CEREBRAL ARTERY DOPPLER INDICES OF OLIGOHYDROMNIOS AND NORMAL AMNIOTIC FLUID LEVELS IN PREGNANT FEMALES Open
Background: Oligohydramnios, defined by reduced amniotic fluid volume, is a significant indicator of placental insufficiency and fetal compromise. Amniotic fluid plays a critical role in cushioning the fetus, supporting pulmonary developme…
View article: Phylogenetic analysis of the enigmatic Kalash population in Pakistan
Phylogenetic analysis of the enigmatic Kalash population in Pakistan Open
The genetic origin of the Kalash, an isolated community in northern Pakistan, have long been a subject of debate. This study aimed at investigating the genetic diversity and ancestral composition of Kalash people using an advanced set of g…
View article: An Integrative Computational Approach for Identifying Cotton Host Plant MicroRNAs with Potential to Abate CLCuKoV-Bur Infection
An Integrative Computational Approach for Identifying Cotton Host Plant MicroRNAs with Potential to Abate CLCuKoV-Bur Infection Open
Cotton leaf curl Kokhran virus-Burewala (CLCuKoV-Bur) has a circular single-stranded ssDNA genome of 2759 nucleotides in length and belongs to the genus Begomovirus (family, Geminiviridae). CLCuKoV-Bur causes cotton leaf curl disease (CLCu…
View article: Serum transferrin level in type-2 diabetic patients in association with sociodemographic profile and dietary habits
Serum transferrin level in type-2 diabetic patients in association with sociodemographic profile and dietary habits Open
The management of type 2 diabetes mellitus (T2DM) involves lifestyle changes. Glycated hemoglobin levels have been found to decrease with proper management of T2DM, which includes medication and dietary adjustments high in key nutrients. I…
View article: First evidence of immunomodulation of the renin-angiotensin system through substance P/neurokinin 1 receptor: a case and control study in hypertension and cardiac patients
First evidence of immunomodulation of the renin-angiotensin system through substance P/neurokinin 1 receptor: a case and control study in hypertension and cardiac patients Open
Gaining knowledge about the differences in substance P (SP) and neurokinin 1 receptor (NK1R) levels between cardiac and hypertensive patients may help clarify how these neuropeptides could be involved in the pathophysiology of cardiovascul…
View article: Dominance of dengue virus serotype-2 in Pakistan (2023–2024): Molecular characterization of the envelope gene and exploration of antiviral targets
Dominance of dengue virus serotype-2 in Pakistan (2023–2024): Molecular characterization of the envelope gene and exploration of antiviral targets Open
View article: SSR Markers-Based DNA Fingerprinting for Varietal Identification in Mango Cultivars
SSR Markers-Based DNA Fingerprinting for Varietal Identification in Mango Cultivars Open
Mango (Mangifera indica L.) is an allotetraploid (2n = 4X= 40) drupe fruit and has high nutritional value belongs to genus Mangifera and family Anacardiaceae. Mango cultivars are used with worldwide acceptance to pharmacological, ethnomedi…
View article: A comprehensive review on phytochemicals as potential therapeutic agents for stress-induced gastric ulcer
A comprehensive review on phytochemicals as potential therapeutic agents for stress-induced gastric ulcer Open
View article: Hypoglycemic, antihyperglycemic, antiglycation, anti-hypercholesteremic, and toxicity evaluation with gas chromatography mass spectrometry profiling for Aloe armatissima leaves
Hypoglycemic, antihyperglycemic, antiglycation, anti-hypercholesteremic, and toxicity evaluation with gas chromatography mass spectrometry profiling for Aloe armatissima leaves Open
Background: Aloe species are known for the treatment of various conditions including diabetes mellitus (DM), hypercholesteremia, and glycation end products. Nevertheless, the biological activity of Aloe armatissima is yet to be reported. I…
View article: Synthesis and Characterization of Graphene Oxide/Polyethylene Glycol/Folic Acid/Brucine Nanocomposites and Their Anticancer Activity on HepG2 Cells
Synthesis and Characterization of Graphene Oxide/Polyethylene Glycol/Folic Acid/Brucine Nanocomposites and Their Anticancer Activity on HepG2 Cells Open
The results of this work demonstrate that GO/PEG/Bru-FA NCs suppress viability and induce apoptosis in HepG2 cells, indicating their potential as an anticancer candidate.
View article: Therapeutic strategy of biological macromolecules based natural bioactive compounds of diabetes mellitus and future perspectives: A systematic review
Therapeutic strategy of biological macromolecules based natural bioactive compounds of diabetes mellitus and future perspectives: A systematic review Open
View article: Antihyperglycemic, antiglycation, anti-hypercholesteremic, and toxicity evaluation with gas chromatography mass spectrometry profiling for <i>Aloe armatissima</i> leaves
Antihyperglycemic, antiglycation, anti-hypercholesteremic, and toxicity evaluation with gas chromatography mass spectrometry profiling for <i>Aloe armatissima</i> leaves Open
Aloe species are known for the treatment of various conditions including diabetes mellitus, hypocholesteremia, and glycation end products. Nevertheless, the biological activity of Aloe armatissima is yet to be reported. It is a first-time …
View article: Graphene oxide/chitosan/manganese/folic acid-brucine functionalized nanocomposites show anticancer activity against liver cancer cells
Graphene oxide/chitosan/manganese/folic acid-brucine functionalized nanocomposites show anticancer activity against liver cancer cells Open
Nanomedicine is the application of nanomaterials and nanotechnology to the development of novel pharmaceuticals and drug delivery mechanisms. The present study synthesized a functionalized nanocomposite (NC) containing graphene oxide (GO),…
View article: Topical Delivery of Terbinafine HCL Using Nanogels: A New Approach to Superficial Fungal Infection Treatment
Topical Delivery of Terbinafine HCL Using Nanogels: A New Approach to Superficial Fungal Infection Treatment Open
This study investigated pH-responsive Terbinafine HCL (TBH)-loaded nanogels as a new approach to treating superficial fungal infections. Acrylic acid (AA) is a synthetic monomer that was crosslinked with a natural polymer (gelatin) using a…
View article: Evaluation of betanin-encapsulated biopolymeric nanoparticles for antitumor activity via PI3K/Akt/mTOR signaling pathway
Evaluation of betanin-encapsulated biopolymeric nanoparticles for antitumor activity via PI3K/Akt/mTOR signaling pathway Open
Cancer nanotheranostic components are useful in monitoring drug delivery and potency against tumor cells. Current chemotherapeutic agents exhibit severe side effects and requires the urgency for discovery of potent therapeutic nano-drugs. …
View article: Neurokinin 1 receptor antagonist along with dexamethasone reduces the inflammation in COVID-19 patients: a novel therapeutic approach
Neurokinin 1 receptor antagonist along with dexamethasone reduces the inflammation in COVID-19 patients: a novel therapeutic approach Open
Background: Corona virus infection is a respiratory infection, compromising the normal breathing in critical patients by damaging the lungs. The aim of this study was to evaluate the clinical outcomes of Substance P receptor Neurokinin 1 a…
View article: Simple Sequence Repeats-Based DNA Fingerprinting and Varietal Identification of Mango Cultivars
Simple Sequence Repeats-Based DNA Fingerprinting and Varietal Identification of Mango Cultivars Open
Assessment of the genetic distinctiveness of a cultivar through morphological descriptors is an important tool for both the registration and the protection. New mango genotypes have been improved using valuable diverse germplasm resources …
View article: Effect of Atenolol on Hepatic Dysfunction by Evaluating Level of AST
Effect of Atenolol on Hepatic Dysfunction by Evaluating Level of AST Open
Hypertension is one of the most important risk factors for morbidity and mortality around the world. Many drugs used to treat hypertension have several side effects. Atenolol used to control hypertension, is an anti-beta-adrenergic agent. …
View article: Septicemia Due to Bed Sores in Patients Admitted at Mayo Hospital Lahore
Septicemia Due to Bed Sores in Patients Admitted at Mayo Hospital Lahore Open
In Pakistan infections, including septicemia and pneumonia, are the leading causes of hospital mortality, followed by malignancy and cardiovascular causes. Objectives: To find the frequency of septicemia in patients due to bed sores in May…
View article: The In Silico Sugarcane Genome-Encoded MicroRNA and Target Network Prediction for Targeting the SCMV
The In Silico Sugarcane Genome-Encoded MicroRNA and Target Network Prediction for Targeting the SCMV Open
Sugarcane mosaic virus (SCMV) is a deleterious pathogen which causes widespread Sugarcane mosaic disease (SCMD) and is classified in the genus Potyvirus (Potyviridae), disseminated by the aphid vector. RNA interference (RNAi)-mediated anti…
View article: COVID-19 and severity of liver diseases: Possible crosstalk and clinical implications
COVID-19 and severity of liver diseases: Possible crosstalk and clinical implications Open
COVID-19-infected individuals and those who recovered from the infection have been demonstrated to have elevated liver enzymes or abnormal liver biochemistries, particularly with preexisting liver diseases, liver metabolic disorders, viral…
View article: The In Silico Sugarcane Genome-Encoded MicroRNA and Target Network Prediction for Targeting the SCMV
The In Silico Sugarcane Genome-Encoded MicroRNA and Target Network Prediction for Targeting the SCMV Open
Sugarcane mosaic virus (SCMV) is a deleterious pathogen which causes widespread Sugarcane mosaic disease (SCMD) and is classified in the genus Potyvirus (Potyviridae), disseminated by the aphid vector. RNA interference (RNAi)-mediated anti…
View article: In Silico Identification of Cassava Genome-Encoded MicroRNAs with Predicted Potential for Targeting the ICMV-Kerala Begomoviral Pathogen of Cassava
In Silico Identification of Cassava Genome-Encoded MicroRNAs with Predicted Potential for Targeting the ICMV-Kerala Begomoviral Pathogen of Cassava Open
Cassava mosaic disease (CMD) is caused by several divergent species belonging to the genus Begomovirus (Geminiviridae) transmitted by the whitefly Bemisia tabaci cryptic species group. In India and other parts of Asia, the Indian cassava m…
View article: Frequency of Anxiety and Depression among Diabetic Patients and Their Association with Hepatorenal Biomarkers
Frequency of Anxiety and Depression among Diabetic Patients and Their Association with Hepatorenal Biomarkers Open
In patients with diabetes, the prevalence of anxiety and depression disorders may be up to two times higher. The aspartate aminotransferase/alanine aminotransferase (AST/ALT) ratio has been used to assess the severity of several chronic li…
View article: Phytochemical D-Pinitol Loaded Graphene Oxide-Chitosan-Folic Acid Nanocomposite Induced Apoptosis in Hepatoma Hepg-2 Cells
Phytochemical D-Pinitol Loaded Graphene Oxide-Chitosan-Folic Acid Nanocomposite Induced Apoptosis in Hepatoma Hepg-2 Cells Open
View article: Study Protocol: Comparison of Magnesium versus Potassium and Their Combined Effect on Insomnia, Sleep Hormones, Insulin Resistance, and Quality of Life among Patients with Diabetes Mellitus
Study Protocol: Comparison of Magnesium versus Potassium and Their Combined Effect on Insomnia, Sleep Hormones, Insulin Resistance, and Quality of Life among Patients with Diabetes Mellitus Open
Insomnia has been associated with changes in metabolism causing irregular insulin secretion, insulin insensitivity, and poor glucose metabolism, increasing the risk of diabetes mellitus. Magnesium and potassium are electrolytes that play a…
View article: Determination of Analgesic Potential of Ethanolic Extract of Brassica campestris Leaves in Rats
Determination of Analgesic Potential of Ethanolic Extract of Brassica campestris Leaves in Rats Open
Pharmacognosy Research,2022,14,3,297-303.DOI:10.5530/pres.14.3.43Published:July 2022Type:Original ArticleAuthors:Abdullah R Alzahrani, and Imran Shahid Author(s) affiliations:Abdullah R Alzahrani, Imran Shahid* Department of Pharmacology a…