Ismail Shah
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View article: Effect of Non-starchy Vegetable Consumption on Weight Status in an Overweight and Obese University Population
Effect of Non-starchy Vegetable Consumption on Weight Status in an Overweight and Obese University Population Open
Background Obesity is a growing public health problem in both developing and developed countries. Negative health-related outcomes such as type II diabetes mellitus (T2DM), cardiovascular disease (CVD), and certain cancers are linked with …
New Lead Schiff Bases Predominantly Mediate Vasorelaxant Activity Through α1 Receptor Blocking Activity Open
Schiff bases synthesized in our laboratory have demonstrated pain-relieving effects through both peripheral and central nervous system pathways. Considering that centrally acting analgesics often affect the muscle tone of the gastrointesti…
Designing and Evaluating Digital Therapeutic Interventions Using Virtual and Augmented Reality to Improve Medication Adherence, Patient Education, and Chronic Disease Self-Management Open
Background: Chronic diseases such as diabetes, hypertension, and COPD are leading causes of global mortality, yet conventional approaches to patient education and medication adherence remain insufficient. Emerging technologies like virtual…
View article: Determination of analgesic potential of Helicteres isora and molecular involvement of opioids and GABA receptors
Determination of analgesic potential of Helicteres isora and molecular involvement of opioids and GABA receptors Open
Herbal medicines are used as a source of therapeutic agents as they are safer and less toxic than synthetic drugs. Several species of Helicteres isora (Sterculiaceae) have been documented in folk medicine to have analgesic properties. This…
Enhancing the Growth and Quality of Alfalfa Fodder in Aridisols through Wise Utilization of Saline Water Irrigation, Adopting a Strategic Leaching Fraction Technique Open
An experiment was conducted to investigate the optimal use of high-salt water for alfalfa fodder growth and quality in Aridisol. The experiment included five treatments and was performed using a completely randomized design (CRD) as factor…
View article: Exploration for the opioidergic, GABAergic and histaminergic potentials of synthesized Schiff’s base derivatives: An in-vivo approach
Exploration for the opioidergic, GABAergic and histaminergic potentials of synthesized Schiff’s base derivatives: An in-vivo approach Open
Herein, five Schiff’s base analogs (designated as AK1 to AK5) were synthesized and screened for their analgesic and anti-inflammatory efficacies. All compounds exhibited analgesic activity at selected doses from 45.31 % to 75.75 %, while t…
View article: Synthesis and Characterization of Silver Nanoparticles Conjugated with Triazole‐N‐acetamide Thiazole Derivatives for Selective Detection of Cymoxanil in Complex Samples
Synthesis and Characterization of Silver Nanoparticles Conjugated with Triazole‐N‐acetamide Thiazole Derivatives for Selective Detection of Cymoxanil in Complex Samples Open
Cymoxanil (CYM) is one of the most important fungicides for various vegetables and fruits. However, its routine detection is still expensive due to high‐cost equipment. In this context, the silver nanoparticle‐based colorimetric probe was …
Hair Growth Promoting Effect Of Topical Poly Herbal Oil On Sprague Dawley Rats Open
Hair loss is a common concern for both men and women, usually characterized by hair thinning, dandruff and extreme hair fall or shedding. Although synthetic remedies for hair loss are available but they often have appalling side effects an…
Effects of Artemisia macrocephala Jacquem on Memory Deficits and Brain Oxidative Stress in Streptozotocin-Induced Diabetic Mice Open
Different species of Artemisia have been reported to have therapeutic potential in treating various health disorders, including diabetes and memory dysfunction. The present study was planned to evaluate the effects of Artemisia macrocephal…
ASSESSMENT OF POTENTIALLY TOXIC METALS AND NUTRIENTS FROM CONTAMINATED SOIL, EDIBLE PLANTS, AND LAKE SEDIMENTS: A CASE STUDY OF HATTAR INDUSTRIAL ESTATE HARIPUR, PAKISTAN Open
An agricultural field located in the vicinity of the Hattar industrial Estate irrigates with industrial wastewater containing potentially toxic metals and excessive nutrients. In this study, onion field soil, wheat field soil, and edible p…
View article: Total scale analysis of organic acids and their role to mitigate Alzheimer's disease
Total scale analysis of organic acids and their role to mitigate Alzheimer's disease Open
Organic acids are specific groups of chemicals that contain COOH in their structures. They have properties of weakly acidic nature and dissolves completely into protons when present in aqueous solutions. In biological systems, organic acid…
View article: GC/MS analysis, anti-leishmanial and relaxant activity of essential oil of Chenopodium ambrosioides (L.) from Malakand region.
GC/MS analysis, anti-leishmanial and relaxant activity of essential oil of Chenopodium ambrosioides (L.) from Malakand region. Open
Chenopodium ambrosioides is abundantly available in Malakand region. As constituents and concentrations of essential oils vary based on its geographical location, we carried our current study to extract and evaluate its possible relaxant a…
PROTECTIVE EFFECT OF FICUS CARICA FRUIT AGAINST CARBON TETRACHLORIDE INDUCED HEPATIC TOXICITY IN MICE Open
Ficus carica (Fig) is considered to be first plant which is cultivated on earth. Fruit of this plant is delicious, medicinally important and is being consumed by human population since centuries. The present study was designed to assess th…
CCDC 1038700: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
CCDC 1038701: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
CCDC 1038699: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
Synthesis, crystal studies and biological evaluation of flavone derivatives. Open
Three substituted flavone derivatives have been synthesized from substituted O-hydroxy acetophenones and 4-trifluoromethyl benzaldehyde in good yield. These compounds were characterized by NMR spectroscopy and single crystal X-ray Diffract…
In vitro and in vivo Antidiabetic Properties of Phenolic Antioxidants From Sedum adenotrichum Open
Natural products serve as the mainstay of human life, and today, almost half of the drugs in clinical practice are the natural origin. Keeping in view the importance of medicinal plants and natural products, Sedum adenotrichum also known a…
Hydrophilically modified self-assembling α-tocopherol derivative as niosomal nanocarrier for improving clarithromycin oral bioavailability Open
Synthesis of biocompatible and cost-effective novel nonionic surfactants from renewable resources has been the subject of greater scientific interest for enhancing the bioavailability of less water-soluble drugs. The present study focuses …
Pharmacological profile of the aerial parts of Rubus ulmifolius Schott Open
The current work confirms that aerial parts of Rubus ulmifolius contain flavonoids that are safe up to 6 g/kg (p.o). Crude methanolic extract and flavonoids rich fraction of Rubus ulmifolius have significant antioxidant and antipyretic act…
Role of Artemisia macrocephala as enzymes inhibitor in dementia and nociception! A pharmacological study Open
This study was conducted for investigating potentials of methanolic extract (Am.CME) and subsequent fractions of Artemisia macrocephala (A.macrocephala) for the inhibition of acetylcholinesterase (AChE), butyrylcholinesterase (BChE) and cy…
A mechanistic approach to anti-nociceptive potential of Artemisia macrocephala Jacquem Open
The results in this study provide evidences that A. macrocrphala has anticonciceptive effects and can be used for treatment of pain in traditional therapies. This study opens a new channel for isolation of analgesic compounds from the spec…
View article: ACUTE TOXICITY AND ANALGESIC ACTIVITY OF CRUDE FLAVONOIDS OF ACHILLEA WILHELMSII AND TEUCRIUM STOCKSIANUM
ACUTE TOXICITY AND ANALGESIC ACTIVITY OF CRUDE FLAVONOIDS OF ACHILLEA WILHELMSII AND TEUCRIUM STOCKSIANUM Open
OBJECTIVES: To isolate total flavonoids from Achillea Wilhelmsii and Teucrium Stocksianum and screen them for possible analgesic activity and to determine the safe dose range of total flavonoids for preclinical studies in mice. METHODS: Ac…