Explanipedia

Distinct maternal DNA methylation associations with gestational age at early and late-mid term pregnancy in a low- and middle-income country: evaluation of biological, genetic, and psychosocial contributors Open

Marcia Smiti Jude, Chaini Konwar, Robyn J. McQuaid, Farooq Ghani, Nazneen Islam , et al. · 2025

Mothers undergo physiological and molecular changes over the course of gestation. These modifications “get under the skin” and may be reflected in the maternal epigenome through processes such as DNA methylation. Such an epigenetic mark ma…

Ambulatory blood pressure levels in individuals with uncontrolled clinic hypertension across Bangladesh, Pakistan, and Sri Lanka Open

Anqi Zhu, Truls Østbye, Aliya Naheed, H Asita de Silva, Imtiaz Jehan , et al. · 2024

Hypertension is a leading risk factor for cardiovascular disease in South Asia. The authors aimed to assess the cross‐country differences in 24‐h ambulatory, daytime, and nighttime systolic blood pressure (SBP) among rural population with …

Estimated Glomerular Filtration Rate, Albuminuria, and Adverse Outcomes Open

Lawrence J. Appel, Morgan E. Grams, Mark Woodward, Katie Harris, Hisatomi Arima , et al. · 2023

Importance Chronic kidney disease (low estimated glomerular filtration rate [eGFR] or albuminuria) affects approximately 14% of adults in the US. Objective To evaluate associations of lower eGFR based on creatinine alone, lower eGFR based …

Post-intervention acceptability of multicomponent intervention for management of hypertension in rural Bangladesh, Pakistan, and Sri Lanka- a qualitative study Open

Tazeen H. Jafar, Saeideh Tavajoh, H Asita de Silva, Aliya Naheed, Imtiaz Jehan , et al. · 2023

Background COBRA-BPS (Control of Blood Pressure and Risk Attenuation-Bangladesh, Pakistan, Sri Lanka), a multicomponent, community health-worker (CHW)-led hypertension management program, has been shown to be effective in rural communities…

Effect of a community based social marketing strategy on the uptake of clean delivery kits in peri-urban communities of Karachi, Pakistan Open

Asra Usmani, Shazia Sultana, Muhammad Imran Nisar, Shehla Zaidi, Imtiaz Jehan , et al. · 2022

Effect of a Community Based Social Marketing Strategy on the Uptake of Clean Delivery Kits in Peri-Urban Communities of Karachi, Pakistan Open

Asra Usmani, Shazia Sultana, Muhammad Imran Nisar, Shehla Zaidi, Imtiaz Jehan , et al. · 2021

Background: Neonatal and maternal mortality is high in Pakistan. More than half of all deliveries take place at homes by unskilled birth attendants and unhygienic practices are common. The objective of our study was to determine the effect…

Total Adverse Childhood Experiences and Preterm Birth: A Systematic Review Open

Salima Sulaiman, Shahirose Sadrudin Premji, Farideh Tavangar, Ilona S. Yim, Margaret Lebold , et al. · 2021

Effect of a Multicomponent Intervention on Antihypertensive Medication Intensification in Rural South Asia: <i>Post Hoc</i> Analysis of a Cluster RCT Open

Liang Feng, Imtiaz Jehan, H Asita de Silva, Aliya Naheed, Aamir Hameed Khan , et al. · 2021

Background Inadequate treatment of hypertension is a widespread problem, especially in South Asian countries where cardiovascular disease mortality rates are high. We aimed to explore the effect of a multicomponent intervention (MCI) on an…

Budget impact and cost-effectiveness analyses of the COBRA-BPS multicomponent hypertension management programme in rural communities in Bangladesh, Pakistan, and Sri Lanka Open

Eric Finkelstein, Anirudh Krishnan, Aliya Naheed, Imtiaz Jehan, H Asita de Silva , et al. · 2021

The global network: a prospective study of stillbirths in developing countries Open

Elizabeth M. McClure, Linda L. Wright, Robert L. Goldenberg, Shivaprasad S. Goudar, Sailajanandan N. Parida , et al. · 2020

Our goal was to determine stillbirth rates in a multi-site population-based study in community settings in the developing world.

Prevalence of Muscle dysmorphia and associated health activities in male medical students in Karachi, Pakistan Open

Imtiaz Jehan, Azza Sarfraz, Ali Faisal Sultan, Mirza Zain Baig, Moheudin Khan , et al. · 2020

Background: Muscle Dysmorphia (MD) is a subtype of body dysmorphic disorder (BDD) and is currently classified under anxiety disorders (subheading: Obsessive-compulsive disorder) in DSM 5. MD is hypothesized to affect the self-esteem and so…

Effects of Essential Newborn Care Training on Fresh Stillbirths and Early Neonatal Deaths by Maternal Education Open

Elwyn Chomba, Wally Carlo, Shivaprasad S. Goudar, Imtiaz Jehan, Antoinette Tshefu , et al. · 2020

Infants of women with lower education levels are at higher risk for perinatal mortality.

A Community-Based Intervention for Managing Hypertension in Rural South Asia Open

Tazeen H. Jafar, Mihir Gandhi, H. Asita de Silva, Imtiaz Jehan, Aliya Naheed , et al. · 2020

In rural communities in Bangladesh, Pakistan, and Sri Lanka, a multicomponent intervention that was centered on proactive home visits by trained government community health workers who were linked with existing public health care infrastru…

Prevalence of Muscle dysmorphia and associated health activities in male medical students in Karachi, Pakistan Open

Azza Sarfraz, Ali Faisal Sultan, Mirza Zain Baig, Moheudin Khan, Noayna Arshad , et al. · 2020

Background: Muscle Dysmorphia (MD) is a subtype of body dysmorphic disorder (BDD) and is currently classified under anxiety disorders (subheading: Obsessivecompulsive disorder) in DSM 5. MD is hypothesized to affect the self-esteem and soc…

Prevalence and correlates of cardiometabolic multimorbidity among hypertensive individuals: a cross-sectional study in rural South Asia—Bangladesh, Pakistan and Sri Lanka Open

Liang Feng, Imtiaz Jehan, H Asita de Silva, Aliya Naheed, Hamida Farazdaq , et al. · 2019

Objective To determinate the prevalence and correlates of cardiometabolic multimorbidity (CMM), and their cross-country variation among individuals with hypertension residing in rural communities in South Asia. Design A cross-sectional stu…

Classifying perinatal mortality using verbal autopsy: is there a role for nonphysicians? Open

Cyril Engmann, John Ditekemena, Imtiaz Jehan, Ana Garcés, Mutinta Phiri , et al. · 2019

Background Because of a physician shortage in many low-income countries, the use of nonphysicians to classify perinatal mortality (stillbirth and early neonatal death) using verbal autopsy could be useful. Objective To determine the extent…

Struggling with long-time low uptake of modern contraceptives in Pakistan Open

Nasim Zahid Shah, Tazeen Saeed Ali, Imtiaz Jehan, Xaher Gul · 2019

Despite a well-designed community-based FP programme, providers' counselling skills need to be enhanced. However, this has to be combined with sufficient training, supportive supervision and contraceptive availability.

Regional Variation in Comorbid Prediabetes and Diabetes and Associated Factors among Hypertensive Individuals in Rural Bangladesh, Pakistan, and Sri Lanka Open

Liang Feng, Aliya Naheed, H Asita de Silva, Imtiaz Jehan, Rubhana Raqib , et al. · 2019

We aimed to explore the cross-country variation in the prevalence of comorbid prediabetes or diabetes and determine the sociodemographic, lifestyle, and clinical factors, especially body mass index (BMI) and waist circumference, associated…

Patients’ experiences on accessing health care services for management of hypertension in rural Bangladesh, Pakistan and Sri Lanka: A qualitative study Open

Helena Legido‐Quigley, Aliya Naheed, H. Asita de Silva, Imtiaz Jehan, Victoria Haldane , et al. · 2019

Hypertension is the leading risk factor for cardiovascular disease and leading cause of premature death globally. In 2008, approximately 40% of adults were diagnosed with hypertension, with more than 1.5 billion people estimated to be affe…

Regional variation in chronic kidney disease and associated factors in hypertensive individuals in rural South Asia: findings from control of blood pressure and risk attenuation—Bangladesh, Pakistan and Sri Lanka Open

Liang Feng, Hithanadura Asita De Silva, Imtiaz Jehan, Aliya Naheed, Anuradhani Kasturiratne , et al. · 2018

Background We aimed to determine the prevalence of chronic kidney disease (CKD) and its cross-country variation among hypertensive individuals in rural Bangladesh, Pakistan and Sri Lanka. We also explored the factors associated with CKD in…

Determinants of Uncontrolled Hypertension in Rural Communities in South Asia—Bangladesh, Pakistan, and Sri Lanka Open

Tazeen H. Jafar, Mihir Gandhi, Imtiaz Jehan, Aliya Naheed, H Asita de Silva , et al. · 2018

BACKGROUND Uncontrolled blood pressure (BP) is a leading risk factor for death and disability in South Asia. We aimed to determine the cross-country variation, and the factors associated with uncontrolled BP among adults treated for hypert…

Albuminuria and kidney function as prognostic marker of left ventricular mass among South Asians with hypertension Open

Liang Feng, Aamir Hameed Khan, Imtiaz Jehan, John Carson Allen, Tazeen H. Jafar · 2017

P6256Large cardiovascular risk burden in rural Bangladesh, Pakistan, and Sri Lanka: design and preliminary findings in a Cluster Randomized Controlled Trial (COBRA-BPS) Open

Tazeen H. Jafar, Mihir Gandhi, Aliya Naheed, Imtiaz Jehan, H.A. De Silva , et al. · 2017

Multicomponent intervention versus usual care for management of hypertension in rural Bangladesh, Pakistan and Sri Lanka: study protocol for a cluster randomized controlled trial Open

Tazeen H. Jafar, Imtiaz Jehan, H. Asita de Silva, Aliya Naheed, Mihir Gandhi , et al. · 2017

Additional file 3: of Multicomponent intervention versus usual care for management of hypertension in rural Bangladesh, Pakistan and Sri Lanka: study protocol for a cluster randomized controlled trial Open

Tazeen H. Jafar, Imtiaz Jehan, H. de Silva, Aliya Naheed, Mihir Gandhi , et al. · 2017

CHW checklist. (PDF 175Â kb)

Knowledge and perception regarding autism among primary school teachers: A cross-sectional survey from Pakistan, South Asia Open

Adil Ayub, Buria Naeem, Wajahat Nazir Ahmed, Suraksha Srichand, Komal Aziz , et al. · 2017

Results suggest that teachers have an inadequate understanding of autism due to several misconceptions. This calls for increased education of teachers with regard to autism and other childhood disorders.

Effects of Essential Newborn Care Training on Fresh Stillbirths and Early Neonatal Deaths by Maternal Education Open

Elwyn Chomba, Wally Carlo, Shivaprasad S. Goudar, Imtiaz Jehan, Antoinette Tshefu , et al. · 2016

Background: Infants of women with lower education levels are at higher risk for perinatal mortality. Objectives: We explored the impact of training birth attendants and pregnant women in the Essential Newborn Ca…

Health Education and General Practitioner Training in Hypertension Management: Long-Term Effects on Kidney Function Open

Tazeen H. Jafar, John Carson Allen, Imtiaz Jehan, Aamir Hameed, Seyed Ehsan Saffari , et al. · 2016

Background and objectives In the Control of Blood Pressure and Risk Attenuation trial, a 2×2 factorial design study (2004–2007), the combined home health education and trained general practitioner intervention delivered over 2 years was mo…

Control of Blood Pressure and Risk Attenuation: Post Trial Follow-Up of Randomized Groups Open

Tazeen H. Jafar, Imtiaz Jehan, Liang Feng, Sylvaine Barbier, Muhammad Islam , et al. · 2015

ClinicalTrials.gov NCT00327574.

Does academic assessment system type affect levels of academic stress in medical students? A cross-sectional study from Pakistan Open

Madiha Ali, Hamna Asim, Ahmed I. Edhi, Muhammad Daniya Hashmi, Muhammad Shahjahan Khan , et al. · 2015

Based on the present study, we suggest governing bodies to revise and employ a uniform assessment system for all the medical colleges to improve student academic performance and at the same time reduce stress levels. Our results indicate t…

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