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View article: P-125. A Single-Center Descriptive Analysis of Cryptosporidiosis in Immunocompromised Patients
P-125. A Single-Center Descriptive Analysis of Cryptosporidiosis in Immunocompromised Patients Open
Background Cryptosporidiosis is usually a self-limiting infection caused by a protozoan, Cryptosporidium spp. In immunocompromised, especially with T cell dysfunction, it can cause severe, potentially life-threatening infection. There is l…
View article: 656. Cryptosporidiosis in Immunocompromised Patients with Cancer Receiving Chemotherapy, CAR-T Cell Therapy and Hematopoietic Stem Cell Transplantation: A Retrospective Analysis
656. Cryptosporidiosis in Immunocompromised Patients with Cancer Receiving Chemotherapy, CAR-T Cell Therapy and Hematopoietic Stem Cell Transplantation: A Retrospective Analysis Open
Background Cryptosporidium is a parasitic protozoan that causes severe and potentially life-threatening diarrheal disease in immunocompromised patients. Infections can be asymptomatic, cause self-limited disease, or chronic diarrhea and in…
View article: CCDC 2262087: Experimental Crystal Structure Determination
CCDC 2262087: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: Reduced Cholesterol Levels during Acute Human Babesiosis
Reduced Cholesterol Levels during Acute Human Babesiosis Open
Background: Babesiosis, an intra-erythrocytic protozoan disease, is an emerging zoonotic parasitic disease worldwide. Cholesterol levels are correlated with severe infections, such as sepsis and COVID-19, and anecdotal reports suggest that…
View article: 1135. Monoclonal Antibody Therapeutics in US Veterans against Delta and Omicron SARS-CoV-2 Variants
1135. Monoclonal Antibody Therapeutics in US Veterans against Delta and Omicron SARS-CoV-2 Variants Open
Background Anti-SARS-CoV-2 monoclonal antibodies (mABs) target the viral spike protein and have been shown to have clinical benefit in treating COVID-19. The FDA had given emergency use authorization to mAB products: bamlanivimab+etesevina…
View article: 734. Abnormal Lipid Profiles in Human Babesiosis
734. Abnormal Lipid Profiles in Human Babesiosis Open
Background Babesiosis has gained attention as an emerging protozoal zoonotic disease with an expanding known incidence and geographical range in the US. The infection is caused by Babesia microti in the US and is transmitted by the bite of…
View article: 554. Clinical Impact of Monoclonal Antibody Therapy with SARS-CoV-2 Infection
554. Clinical Impact of Monoclonal Antibody Therapy with SARS-CoV-2 Infection Open
Background The novel coronavirus SARS-CoV2 is the causative agent for COVID-19 responsible for the ongoing global pandemic. The spike protein on its surface binds to the angiotensin-converting enzyme 2 receptor helps to enter human cells. …
View article: Upper Respiratory Tract Symptoms
Upper Respiratory Tract Symptoms Open
To the Editor: Human rhinovirus (HRV) is the most common cause of upper respiratory tract infection worldwide, nearly year-round.1 Clinical manifestations of HRV infection can be similar to those caused by the severe respiratory syndrome c…
View article: A Case of Severe Psychosis Due to Cushing's Syndrome Secondary to Primary Bilateral Macronodular Adrenal Hyperplasia
A Case of Severe Psychosis Due to Cushing's Syndrome Secondary to Primary Bilateral Macronodular Adrenal Hyperplasia Open
Hypercortisolism is a multisystem disorder that results from inappropriate and excessive glucocorticoid secretion and loss of normal feedback mechanisms of the hypothalamic-pituitary axis. It is broadly divided into adrenocorticotropic hor…
View article: Barriers to Successful Linkage to Care Among HCV Positive Individuals Presenting to a Major Tertiary Medical Center on Long Island, New York
Barriers to Successful Linkage to Care Among HCV Positive Individuals Presenting to a Major Tertiary Medical Center on Long Island, New York Open
In 2013, the US Preventive Services Task Force made a grade B recommendation to offer HCV screening for at-risk individuals and baby boomers (born between 1945 and 1965). However, only 50% of HCV-positive individuals are aware they are inf…
View article: Antibody-Based Immunotherapy To Treat and Prevent Infection with Hypervirulent Klebsiella pneumoniae
Antibody-Based Immunotherapy To Treat and Prevent Infection with Hypervirulent Klebsiella pneumoniae Open
Hypervirulent Klebsiella pneumoniae (hv Kp ) strains are predicted to become a major threat in Asia if antibiotic resistance continues to spread. Anticapsular antibodies (Abs) were developed because disseminated infections caused by hv Kp …