Indraja D. Dev
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View article: IMG-75. MULTI-PARAMETRIC APPROACH FOR DIFFERENTIATING GLIOBLASTOMA, PRIMARY CENTRAL NERVOUS SYSTEM LYMPHOMA AND METASTASIS BY USING PERFUSION AND DIFFUSION TECHNIQUES ON MRI
IMG-75. MULTI-PARAMETRIC APPROACH FOR DIFFERENTIATING GLIOBLASTOMA, PRIMARY CENTRAL NERVOUS SYSTEM LYMPHOMA AND METASTASIS BY USING PERFUSION AND DIFFUSION TECHNIQUES ON MRI Open
BACKGROUND Glioblastoma (GBM), primary lymphomas and metastases at times can have overlapping features on magnetic resonance imaging. In our study we used the advanced neuroimaging applications and calculated percentage signal recovery (PS…
View article: NCMP-20. Incidence of seizures and practice patterns of antiseizure medications in primary supratentorial brain tumors: results from a prospective study
NCMP-20. Incidence of seizures and practice patterns of antiseizure medications in primary supratentorial brain tumors: results from a prospective study Open
BACKGROUND Seizures are frequently associated in patients with supratentorial brain tumors, causing a significant impact on the quality of life of patients. The practice of using antiseizure medications (ASM) is widely variable in the comm…
View article: PReCedeNT trial: Phase III randomized-controlled trial of Lutetium − 177 DOTATATE Peptide Receptor Radionuclide Therapy (PRRT) plus Chemotherapy versus PRRT alone in FDG-avid, Well-differentiated Gastroenteropancreatic neuroendocrine tumors (GEP-NETs)
PReCedeNT trial: Phase III randomized-controlled trial of Lutetium − 177 DOTATATE Peptide Receptor Radionuclide Therapy (PRRT) plus Chemotherapy versus PRRT alone in FDG-avid, Well-differentiated Gastroenteropancreatic neuroendocrine tumors (GEP-NETs) Open
View article: Study protocol of short versus long-term levetiracetam in brain tumors (LIBRA): a phase 3 randomized controlled trial
Study protocol of short versus long-term levetiracetam in brain tumors (LIBRA): a phase 3 randomized controlled trial Open
View article: Study Protocol of a Prospective Phase 2 Study of Chlorophyllin for the Management of Brain Radionecrosis in Patients With Diffuse Glioma (<scp>CHROME</scp>)
Study Protocol of a Prospective Phase 2 Study of Chlorophyllin for the Management of Brain Radionecrosis in Patients With Diffuse Glioma (<span>CHROME</span>) Open
Introduction Chlorophyllin (CHL) effectively decreases the side effects of radiotherapy (RT) by scavenging radiation‐induced free radicals and reactive oxygen species in preclinical trials. This study aims to assess the efficacy of oral CH…
View article: FET PET to differentiate between post-treatment changes and recurrence in high-grade gliomas: a single center multidisciplinary clinic controlled study
FET PET to differentiate between post-treatment changes and recurrence in high-grade gliomas: a single center multidisciplinary clinic controlled study Open
View article: Current and Future Perspectives of PDL1 PET and SPECT Imaging
Current and Future Perspectives of PDL1 PET and SPECT Imaging Open
Programmed Death 1 (PD1) and Programmed Death Ligand (PDL1) play a crucial role in tumor microenvironment by helping cancer cells evade innate immunity. Numerous inhibitor anticancer drugs targeting this interplay have been used in clinica…
View article: Preliminary evaluation of FAPI-04-PET/CT for differentiating recurrence and post-treatment changes in high-grade gliomas
Preliminary evaluation of FAPI-04-PET/CT for differentiating recurrence and post-treatment changes in high-grade gliomas Open
Fibroblast-activated protein (FAP) expression in glial cells is attributed to FAP-positive foci on tumor vessels and neoplastic cells. Preclinical and pilot studies have shown FAP expression in high-grade gliomas. We aimed at comparing PET…
View article: Study Protocol of Short versus Long-term Levetiracetam in Brain Tumors (LIBRA): A Phase 3 Randomized Controlled Trial
Study Protocol of Short versus Long-term Levetiracetam in Brain Tumors (LIBRA): A Phase 3 Randomized Controlled Trial Open
Background: Seizures are common in patients with brain tumors, impacting daily life and healthcare burden. In contemporary neuro-oncology practice, levetiracetam is the most commonly prescribed antiepileptic drug (AED). Although the practi…
View article: Study Protocol of a Prospective Phase 2 Study of Chlorophyllin for the Management of Brain Radionecrosis in Patients with Diffuse Glioma (CHROME)
Study Protocol of a Prospective Phase 2 Study of Chlorophyllin for the Management of Brain Radionecrosis in Patients with Diffuse Glioma (CHROME) Open
Introduction: Chlorophyllin (CHL) effectively decreases the side effects of radiotherapy (RT) by scavenging radiation-induced free radicals and reactive oxygen species in preclinical trials. This study aims to assess the efficacy of oral C…
View article: Factors Predicting Prognosis in Metastatic Grade 1 Gastro-entero-pancreatic Neuroendocrine Tumors
Factors Predicting Prognosis in Metastatic Grade 1 Gastro-entero-pancreatic Neuroendocrine Tumors Open
Introduction The incidence of gastroenteropancreatic neuroendocrine tumors (GEP-NET) has steadily increased. These tumors are considered relatively indolent even when metastatic. What determines survival outcomes in such situations is unde…
View article: Rare Cases of Extracranial Metastases from High-grade Glioma Detected on FET PET-CT with Histopathological Confirmation
Rare Cases of Extracranial Metastases from High-grade Glioma Detected on FET PET-CT with Histopathological Confirmation Open
Extracranial metastasis from high-grade glial tumors is an extremely rare condition with its reported incidence being <1%. The most common sites reported in the literature are leptomeninges and spinal cord, followed by the liver, lung, and…
View article: Intra-arterial PRRT with Lu-177 DOTATATE in Liver-dominant Metastatic Neuroendocrine Tumors: Early Assessment of Efficacy and Toxicity
Intra-arterial PRRT with Lu-177 DOTATATE in Liver-dominant Metastatic Neuroendocrine Tumors: Early Assessment of Efficacy and Toxicity Open
Purpose: We proposed to administer Lu-177-DOTATATE in intra-arterial (IA) mode for higher first-pass localization to somatostatin receptors, higher residence time in liver metastases, and more radiation to tumor. This study aimed at assess…
View article: Tata Memorial Centre Evidence Based Use of Nuclear medicine diagnostic and treatment modalities in cancer
Tata Memorial Centre Evidence Based Use of Nuclear medicine diagnostic and treatment modalities in cancer Open
PET/CT and radioisotope therapy are diagnostic and therapeutic arms of Nuclear Medicine, respectively. With the emergence of better technology, PET/CT has become an accessible modality. Diagnostic tracers exploring disease-specific targets…
View article: PATH-10. SURGICALLY RESECTED RECURRENT DIFFUSE GLIOMAS: HISTOMOLECULAR SPECTRUM
PATH-10. SURGICALLY RESECTED RECURRENT DIFFUSE GLIOMAS: HISTOMOLECULAR SPECTRUM Open
Histological treatment-related changes (TRC) may mimic radiological progression in diffuse-gliomas on follow-up after complete therapy. If scans suggest recurrence, patients undergo re-surgery& re-RT, if recurrence is histologically confir…
View article: Molecular Imaging of Glial Tumors: Established and Emerging Tracers
Molecular Imaging of Glial Tumors: Established and Emerging Tracers Open
Various positron emission tomography (PET) tracers have been developed and extensively studied in the field of neuro-oncology imaging. In the management of brain tumors, accurate delineation of tumor extent, assessment of treatment respons…
View article: The complementary role of MRI and FET PET in high-grade gliomas to differentiate recurrence from radionecrosis
The complementary role of MRI and FET PET in high-grade gliomas to differentiate recurrence from radionecrosis Open
Introduction Conventional magnetic resonance imaging (MRI) has limitations in differentiating tumor recurrence (TR) from radionecrosis (RN) in high-grade gliomas (HGG), which can present with morphologically similar appearances. Multiparam…
View article: Imaging-Based Patterns of Failure following Re-Irradiation for Recurrent/Progressive High-Grade Glioma
Imaging-Based Patterns of Failure following Re-Irradiation for Recurrent/Progressive High-Grade Glioma Open
Background: Re-irradiation (ReRT) is an effective treatment modality in appropriately selected patients with recurrent/progressive high-grade glioma (HGG). The literature is limited regarding recurrence patterns following ReRT, which was i…
View article: Primary Neuroendocrine Tumor of Prostate in a Case of Metastatic Adenocarcinoma of Lung
Primary Neuroendocrine Tumor of Prostate in a Case of Metastatic Adenocarcinoma of Lung Open
Neuroendocrine tumor (NET) of the prostate is an extremely rare entity which represents <1% of the prostatic cancers, but with increasing incidence. Its spectrum encompasses several histological variants ranging from well-differentiated tu…
View article: Rare Presentation of Radiation-induced Sarcoma Detected on F-18 FDG Positron Emission Tomography/Computed Tomography in a Treated Case of Giant Cell Tumor
Rare Presentation of Radiation-induced Sarcoma Detected on F-18 FDG Positron Emission Tomography/Computed Tomography in a Treated Case of Giant Cell Tumor Open
Giant cell tumors (GCTs) are benign bone lesions which are treated with curettage and bone grafting. Infrequently, GCTs show local site recurrences which are then treated with either surgical excision or radiation therapy. Radiation-induce…
View article: All that Glitters on PSMA is Not a Lesion
All that Glitters on PSMA is Not a Lesion Open
Nonspecific uptake of prostate-specific membrane antigen (PSMA) on PSMA positron-emission tomography/computed tomography (CT) is normally encountered in benign conditions, which is detected on morphological changes on CT component. However…
View article: Utility of FET-PET in detecting high-grade gliomas presenting with equivocal MR imaging features
Utility of FET-PET in detecting high-grade gliomas presenting with equivocal MR imaging features Open
High-grade gliomas, metastases, and primary central nervous system lymphoma (PCNSL) are common high-grade brain lesions, which may have overlapping features on magnetic resonance (MR) imaging. Our objective was to assess the utility of 18-…