Inés Herrero-Fernández
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View article: Caecum OX40+CD4 T-cell subset associates with mucosal damage and key markers of disease in treated HIV-infection
Caecum OX40+CD4 T-cell subset associates with mucosal damage and key markers of disease in treated HIV-infection Open
High frequencies of caecum OX40+CD4 T-cells are found in people with HIV (PWH) and successful viral control. Interestingly, this cellular subset reflects key markers of disease and peripheral T-cell activation, as well as HIV-driven mucosa…
View article: Partial restoration of gut‐mucosal dysbiosis in late‐treated HIV‐infected subjects with CD4 T‐cell recovery
Partial restoration of gut‐mucosal dysbiosis in late‐treated HIV‐infected subjects with CD4 T‐cell recovery Open
Peer reviewed
View article: Immunological features beyond CD4/CD8 ratio values in older individuals
Immunological features beyond CD4/CD8 ratio values in older individuals Open
The CD4/CD8 T-cell ratio is emerging as a relevant marker of evolution for many pathologies and therapies. We aimed to explore immunological features beyond CD4/CD8 ratio values in older subjects (>65 years old) who were classified as havi…
View article: Effect of homeostatic T-cell proliferation in the vaccine responsiveness against influenza in elderly people
Effect of homeostatic T-cell proliferation in the vaccine responsiveness against influenza in elderly people Open
View article: Improved CD4 T cell profile in HIV-infected subjects on maraviroc-containing therapy is associated with better responsiveness to HBV vaccination
Improved CD4 T cell profile in HIV-infected subjects on maraviroc-containing therapy is associated with better responsiveness to HBV vaccination Open
View article: HIV-Infected Subjects With Poor CD4 T-Cell Recovery Despite Effective Therapy Express High Levels of OX40 and α4β7 on CD4 T-Cells Prior Therapy Initiation
HIV-Infected Subjects With Poor CD4 T-Cell Recovery Despite Effective Therapy Express High Levels of OX40 and α4β7 on CD4 T-Cells Prior Therapy Initiation Open
Our results are compatible with exacerbated HP processes in immunodiscordant subjects, already before the cART onset.
View article: An in vitro system of autologous lymphocytes culture that allows the study of homeostatic proliferation mechanisms in human naive CD4 T-cells
An in vitro system of autologous lymphocytes culture that allows the study of homeostatic proliferation mechanisms in human naive CD4 T-cells Open
View article: Association between a Suppressive Combined Antiretroviral Therapy Containing Maraviroc and the Hepatitis B Virus Vaccine Response
Association between a Suppressive Combined Antiretroviral Therapy Containing Maraviroc and the Hepatitis B Virus Vaccine Response Open
The response to the HBV vaccine in HIV-infected patients is deficient. Our aim was to analyze whether a suppressive combined antiretroviral treatment (cART) containing maraviroc (MVC-cART) was associated with a better response to HBV vacci…
View article: A Lower Baseline CD4/CD8 T-Cell Ratio Is Independently Associated with Immunodiscordant Response to Antiretroviral Therapy in HIV-Infected Subjects
A Lower Baseline CD4/CD8 T-Cell Ratio Is Independently Associated with Immunodiscordant Response to Antiretroviral Therapy in HIV-Infected Subjects Open
We explored if baseline CD4/CD8 T-cell ratio is associated with immunodiscordant response to antiretroviral therapy in HIV-infected subjects. Comparing immunodiscordant and immunoconcordant subjects matched by pretreatment CD4 counts, we o…
View article: Thymic Function Impacts the Peripheral CD4/CD8 Ratio of HIV-Infected Subjects
Thymic Function Impacts the Peripheral CD4/CD8 Ratio of HIV-Infected Subjects Open
Our data indicate the relevance of the remaining thymic function before the start of treatment to the CD4/CD8 ratio of HIV- infected subjects and, hence, potentially, in their clinical progression.
View article: The formation of titan cells in<i>Cryptococcus neoformans</i>depends on the mouse strain and correlates with induction of Th2-type responses
The formation of titan cells in<i>Cryptococcus neoformans</i>depends on the mouse strain and correlates with induction of Th2-type responses Open
Cryptococcus neoformans is a pathogenic yeast that can form titan cells in the lungs, which are fungal cells of abnormal enlarged size. Little is known about the factors that trigger titan cells. In particular, it is not known how the host…