Inger Andersson
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View article: Light-dependent flavin redox and adduct states control the conformation and DNA-binding activity of the transcription factor EL222
Light-dependent flavin redox and adduct states control the conformation and DNA-binding activity of the transcription factor EL222 Open
The activity of the light-oxygen-voltage/helix-turn-helix (LOV–HTH) photoreceptor EL222 is regulated through protein–protein and protein–DNA interactions, both triggered by photo-excitation of its flavin mononucleotide (FMN) cofactor. To g…
View article: Light-dependent flavin redox and adduct states control the conformation and DNA binding activity of the transcription factor EL222
Light-dependent flavin redox and adduct states control the conformation and DNA binding activity of the transcription factor EL222 Open
The activity of the transcription factor EL222 is regulated through protein-chromophore adduct formation, interdomain dynamics, oligomerization and protein-DNA interactions, all triggered by photo-excitation of its flavin mononucleotide (F…
View article: Genetically encoded non‐canonical amino acids reveal asynchronous dark reversion of chromophore, backbone, and side‐chains in <scp>EL222</scp>
Genetically encoded non‐canonical amino acids reveal asynchronous dark reversion of chromophore, backbone, and side‐chains in <span>EL222</span> Open
Photoreceptors containing the light‐oxygen‐voltage (LOV) domain elicit biological responses upon excitation of their flavin mononucleotide (FMN) chromophore by blue light. The mechanism and kinetics of dark‐state recovery are not well unde…
View article: Genetically encoded non-canonical amino acids reveal asynchronous dark reversion of chromophore, backbone and side-chains in EL222
Genetically encoded non-canonical amino acids reveal asynchronous dark reversion of chromophore, backbone and side-chains in EL222 Open
Photoreceptors containing the light-oxygen-voltage (LOV) domain elicit biological responses upon excitation of their flavin mononucleotide (FMN) chromophore by blue light. The mechanism and kinetics of dark-state recovery are not well unde…
View article: Electrospray sample injection for single-particle imaging with x-ray lasers
Electrospray sample injection for single-particle imaging with x-ray lasers Open
Electrospray contaminant-free delivery of proteins to x-ray laser heralds the start of single-protein x-ray diffractive imaging.
View article: Experimental strategies for imaging bioparticles with femtosecond hard X-ray pulses. Corrigendum
Experimental strategies for imaging bioparticles with femtosecond hard X-ray pulses. Corrigendum Open
Corrections to the article by Daurer et al. [ IUCrJ (2017). 4 , 251–262] are given.
View article: Electrospray sample injection for single-particle imaging with X-ray lasers
Electrospray sample injection for single-particle imaging with X-ray lasers Open
The possibility of imaging single proteins constitutes an exciting challenge for X-ray lasers. Despite encouraging results on large particles, imaging small particles has proven to be difficult for two reasons: not quite high enough pulse …
View article: Structural and functional analyses of Rubisco from arctic diatom species reveal unusual posttranslational modifications
Structural and functional analyses of Rubisco from arctic diatom species reveal unusual posttranslational modifications Open
The catalytic performance of the major CO2-assimilating enzyme, ribulose-1,5-bisphosphate carboxylase/oxygenase (Rubisco), restricts photosynthetic productivity. Natural diversity in the catalytic properties of Rubisco indicates possibilit…
View article: The elusive ligand complexes of the DWARF14 strigolactone receptor
The elusive ligand complexes of the DWARF14 strigolactone receptor Open
Strigolactones, a group of terpenoid lactones, control many aspects of plant growth and development, but the active forms of these plant hormones and their mode of action at the molecular level are still unknown. The strigolactone protein …
View article: Structure of Rubisco from<i>Arabidopsis thaliana</i>in complex with 2-carboxyarabinitol-1,5-bisphosphate
Structure of Rubisco from<i>Arabidopsis thaliana</i>in complex with 2-carboxyarabinitol-1,5-bisphosphate Open
The crystal structure of ribulose-1,5-bisphosphate carboxylase/oxygenase (Rubisco) from Arabidopsis thaliana is reported at 1.5 Å resolution. In light of the importance of A. thaliana as a model organism for understanding higher plant biol…
View article: Experimental strategies for imaging bioparticles with femtosecond hard X-ray pulses
Experimental strategies for imaging bioparticles with femtosecond hard X-ray pulses Open
This study explores the capabilities of the Coherent X-ray Imaging Instrument at the Linac Coherent Light Source to image small biological samples. The weak signal from small samples puts a significant demand on the experiment. Aerosolized…
View article: Crystal structures of β-carboxysome shell protein CcmP: ligand binding correlates with the closed or open central pore
Crystal structures of β-carboxysome shell protein CcmP: ligand binding correlates with the closed or open central pore Open
Cyanobacterial CO2 fixation is promoted by encapsulating and co-localizing the CO2-fixing enzymes within a protein shell, the carboxysome. A key feature of the carboxysome is its ability to control selectively the flux of metabolites in an…
View article: A unique structural domain in Methanococcoides burtonii ribulose-1,5-bisphosphate carboxylase/oxygenase (Rubisco) acts as a small subunit mimic
A unique structural domain in Methanococcoides burtonii ribulose-1,5-bisphosphate carboxylase/oxygenase (Rubisco) acts as a small subunit mimic Open
The catalytic inefficiencies of the CO2-fixing enzyme ribulose-1,5-bisphosphate carboxylase/oxygenase (Rubisco) often limit plant productivity. Strategies to engineer more efficient plant Rubiscos have been hampered by evolutionary constra…
View article: Open data set of live cyanobacterial cells imaged using an X-ray laser
Open data set of live cyanobacterial cells imaged using an X-ray laser Open
Structural studies on living cells by conventional methods are limited to low resolution because radiation damage kills cells long before the necessary dose for high resolution can be delivered. X-ray free-electron lasers circumvent this p…