Inger Dalsgaard
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View article: Validation of a QTL associated with resistance to Vibrio anguillarum in rainbow trout (Oncorhynchus mykiss)
Validation of a QTL associated with resistance to Vibrio anguillarum in rainbow trout (Oncorhynchus mykiss) Open
Vibriosis is a bacterial disease in fish caused by the Gram negative bacterium Vibrio anguillarum with severe impact on rainbow trout ( Oncorhynchus mykiss ) farming. Sustainable control methods should be developed and we here show that ma…
View article: Validation of a QTL for Flavobacterium psychrophilum resistance in rainbow trout Oncorhynchus mykiss
Validation of a QTL for Flavobacterium psychrophilum resistance in rainbow trout Oncorhynchus mykiss Open
Flavobacterium psychrophilum is the causative agent of Bacterial Cold Water Disease (BCWD)/ Rainbow Trout Fry Syndrome (RTFS) in rainbow trout Oncorhynchus mykiss. The disease is associated with significant mortality in trout farms and the…
View article: Fast and accurate identification by <scp>MALDI‐TOF</scp> of the zoonotic serovar E of <i>Vibrio vulnificus</i> linked to eel culture
Fast and accurate identification by <span>MALDI‐TOF</span> of the zoonotic serovar E of <i>Vibrio vulnificus</i> linked to eel culture Open
Vibrio vulnificus is a zoonotic pathogen that can cause death by septicaemia in farmed fish (mainly eels) and humans. The zoonotic strains that have been isolated from diseased eels and humans after eel handling belong to clade E (or serov…
View article: Flavobacterium psychrophilum: Response of Vaccinated Large Rainbow Trout to Different Strains
Flavobacterium psychrophilum: Response of Vaccinated Large Rainbow Trout to Different Strains Open
Background: Although Flavobacterium psychrophilum is recognized as the causative pathogen of rainbow trout fry syndrome (RTFS), often resulting in high fry mortality, it is also responsible for bacterial cold water disease (BCWD) in large …
View article: Reversible mutations in gliding motility and virulence genes: A flexible and efficient phage defence mechanism in <i>Flavobacterium psychrophilum</i>
Reversible mutations in gliding motility and virulence genes: A flexible and efficient phage defence mechanism in <i>Flavobacterium psychrophilum</i> Open
Flavobacteria are among the most important pathogens in freshwater salmonid aquaculture worldwide. Due to concerns regarding development of antibiotic resistance, phage therapy has been proposed as a solution to decrease pathogen load. How…
View article: The Gut Microbiota of Healthy and Flavobacterium psychrophilum-Infected Rainbow Trout Fry Is Shaped by Antibiotics and Phage Therapies
The Gut Microbiota of Healthy and Flavobacterium psychrophilum-Infected Rainbow Trout Fry Is Shaped by Antibiotics and Phage Therapies Open
In the aquaculture sector, there is an increased interest in developing environmentally friendly alternatives to antibiotics in the treatment and prevention of bacterial infections. This requires an understanding of the effects of differen…
View article: Immersion vaccines against <i>Yersinia ruckeri</i> infection in rainbow trout: Comparative effects of strain differences
Immersion vaccines against <i>Yersinia ruckeri</i> infection in rainbow trout: Comparative effects of strain differences Open
The protective effects of autogenous and commercial ERM immersion vaccines (bacterins based on Yersinia ruckeri, serotype O1, biotypes 1 and 2) for rainbow trout ( Oncorhynchus mykiss ) were compared in order to evaluate whether the use of…
View article: Comparative Genomic Analyses of Flavobacterium psychrophilum Isolates Reveals New Putative Genetic Determinants of Virulence Traits
Comparative Genomic Analyses of Flavobacterium psychrophilum Isolates Reveals New Putative Genetic Determinants of Virulence Traits Open
The fish pathogen Flavobacterium psychrophilum is currently one of the main pathogenic bacteria hampering the productivity of salmonid farming worldwide. Although putative virulence determinants have been identified, the genetic basis for …
View article: Interactions between Rainbow Trout Eyed Eggs and Flavobacterium spp. Using a Bath Challenge Model: Preliminary Evaluation of Bacteriophages as Pathogen Control Agents
Interactions between Rainbow Trout Eyed Eggs and Flavobacterium spp. Using a Bath Challenge Model: Preliminary Evaluation of Bacteriophages as Pathogen Control Agents Open
The microbial community surrounding fish eyed eggs can harbor pathogenic bacteria. In this study we focused on rainbow trout (Oncorhynchus mykiss) eyed eggs and the potential of bacteriophages against the pathogenic bacteria Flavobacterium…
View article: Phage-Mediated Control of Flavobacterium psychrophilum in Aquaculture: In vivo Experiments to Compare Delivery Methods
Phage-Mediated Control of Flavobacterium psychrophilum in Aquaculture: In vivo Experiments to Compare Delivery Methods Open
Phage-based approaches have gained increasing interest as sustainable alternative strategies to antibiotic treatment or as prophylactic measures against disease outbreaks in aquaculture. The potential of three methods (oral, bath, and inje…
View article: A Major QTL for Resistance to Vibrio anguillarum in Rainbow Trout
A Major QTL for Resistance to Vibrio anguillarum in Rainbow Trout Open
Genetic selection of disease resistant fish is a major strategy to improve health, welfare and sustainability in aquaculture. Mapping of single nucleotide polymorphisms (SNP) in the fish genome may be a fruitful tool to define relevant qua…
View article: Analysis of 44 Vibrio anguillarum genomes reveals high genetic diversity
Analysis of 44 Vibrio anguillarum genomes reveals high genetic diversity Open
Vibriosis, a hemorrhagic septicemic disease caused by the bacterium Vibrio anguillarum , is an important bacterial infection in Danish sea-reared rainbow trout. Despite of vaccination, outbreaks still occur, likely because the vaccine is b…
View article: Influence of incubation time on antimicrobial susceptibility testing of pathogenic Vibrio anguillarum and Vibrio vulnificus isolated from fish
Influence of incubation time on antimicrobial susceptibility testing of pathogenic Vibrio anguillarum and Vibrio vulnificus isolated from fish Open
A multi-laboratory study was performed to investigate the most suitable incubation time for susceptibility tests of fish pathogens Vibrio anguillarum and Vibrio vulnificus performed at 28 degrees C. An isolate set consisting of 30 V. angui…
View article: MALDI-TOF MS: a diagnostic tool for identification of bacterial fish pathogens
MALDI-TOF MS: a diagnostic tool for identification of bacterial fish pathogens Open
Traditional methods to identify bacterial pathogens involved in fish diseases are often slow and/or costly. Matrix-Assisted Laser Desorption Ionization Time-Of-Flight mass spectrometry (MALDI-TOF MS) is an established, fast, accurate and c…
View article: Phenotypic and Genetic Predictors of Pathogenicity and Virulence in Flavobacterium psychrophilum
Phenotypic and Genetic Predictors of Pathogenicity and Virulence in Flavobacterium psychrophilum Open
Flavobacterium psychrophilum causes bacterial cold-water disease (BCWD) in farmed rainbow trout (Oncorhynchus mykiss), with the multilocus sequence typing (MLST) clonal complex (CC) CC-ST10 accounting for the majority of outbreaks globally…
View article: Inhibition Activity of Compounds and Bacteriophages against <i>Flavobacterium psychrophilum</i> Biofilms In Vitro
Inhibition Activity of Compounds and Bacteriophages against <i>Flavobacterium psychrophilum</i> Biofilms In Vitro Open
Flavobacterium psychrophilum produces biofilms under laboratory conditions, and it has been inconclusively suggested that F. psychrophilum biofilms can be a potential reservoir for transmission of the pathogen to a fish population under fi…
View article: Biogeography of the fish pathogen Aeromonas salmonicida inferred by vapA genotyping
Biogeography of the fish pathogen Aeromonas salmonicida inferred by vapA genotyping Open
A recently described typing system based on sequence variation in the virulence array protein (vapA) gene, encoding the A-layer surface protein array, allows unambiguous subtyping of Aeromonas salmonicida. In the present study, we compile …
View article: Molecular Epidemiology of Photobacterium damselae subsp. damselae Outbreaks in Marine Rainbow Trout Farms Reveals Extensive Horizontal Gene Transfer and High Genetic Diversity
Molecular Epidemiology of Photobacterium damselae subsp. damselae Outbreaks in Marine Rainbow Trout Farms Reveals Extensive Horizontal Gene Transfer and High Genetic Diversity Open
The marine bacterium Photobacterium damselae subsp. damselae is a pathogen for a variety of marine animals, as well as for humans, and is nowadays considered an emerging pathogen for fish of importance in marine aquaculture. Recent studies…
View article: Genomic Diversity and Evolution of the Fish Pathogen Flavobacterium psychrophilum
Genomic Diversity and Evolution of the Fish Pathogen Flavobacterium psychrophilum Open
Flavobacterium psychrophilum, the etiological agent of rainbow trout fry syndrome and bacterial cold-water disease in salmonid fish, is currently one of the main bacterial pathogens hampering the productivity of salmonid farming worldwide.…
View article: Epidemiology of Danish Aeromonas salmonicida subsp. salmonicida in Fish Farms Using Whole Genome Sequencing
Epidemiology of Danish Aeromonas salmonicida subsp. salmonicida in Fish Farms Using Whole Genome Sequencing Open
Furunculosis, a serious infection caused by the bacterium Aeromonas salmonicida subsp. salmonicida is common in sea-reared rainbow trout production in Denmark. Developing an effective control strategy requires knowledge of the epidemiology…
View article: Genomic Characterization of Flavobacterium psychrophilum Serotypes and Development of a Multiplex PCR-Based Serotyping Scheme
Genomic Characterization of Flavobacterium psychrophilum Serotypes and Development of a Multiplex PCR-Based Serotyping Scheme Open
Flavobacterium psychrophilum is a devastating bacterial pathogen of salmonids reared in freshwater worldwide. So far, serological diversity between isolates has been described but the underlying molecular factors remain unknown. By combini…
View article: Subunit vaccine candidates against Aeromonas salmonicida in rainbow trout Oncorhynchus mykiss
Subunit vaccine candidates against Aeromonas salmonicida in rainbow trout Oncorhynchus mykiss Open
Aeromonas salmonicida subsp. salmonicida is the etiological agent of furunculosis and a major fish health problem in salmonid aquaculture worldwide. Injection vaccination with commercial mineral oil-adjuvanted bacterin vaccines has been pa…
View article: Antigen Uptake during Different Life Stages of Zebrafish (Danio rerio) Using a GFP-Tagged Yersinia ruckeri
Antigen Uptake during Different Life Stages of Zebrafish (Danio rerio) Using a GFP-Tagged Yersinia ruckeri Open
Immersion-vaccines (bacterins) are routinely used for aquacultured rainbow trout to protect against Yersinia ruckeri (Yr). During immersion vaccination, rainbow trout take up and process the antigens, which induce protection. The zebrafish…