Ingrid Ehrlich
YOU?
Author Swipe
View article: Slow-wave sleep drives sleep-dependent renormalization of synaptic AMPA receptor levels in the hypothalamus
Slow-wave sleep drives sleep-dependent renormalization of synaptic AMPA receptor levels in the hypothalamus Open
According to the synaptic homeostasis hypothesis (SHY), sleep serves to renormalize synaptic connections that have been potentiated during the prior wake phase due to ongoing encoding of information. SHY focuses on glutamatergic synaptic s…
View article: Limits of the detection of microplastics in fish tissue using stimulated Raman scattering microscopy
Limits of the detection of microplastics in fish tissue using stimulated Raman scattering microscopy Open
We demonstrate the detection sensitivity of microplastic beads within fish tissue using stimulated Raman scattering (SRS) microscopy. The intrinsically provided chemical contrast distinguishes different types of plastic compounds within fi…
View article: Fear Memory Retrieval Is Associated With a Reduction in AMPA Receptor Density at Thalamic to Amygdala Intercalated Cell Synapses
Fear Memory Retrieval Is Associated With a Reduction in AMPA Receptor Density at Thalamic to Amygdala Intercalated Cell Synapses Open
The amygdala plays a crucial role in attaching emotional significance to environmental cues. Its intercalated cell masses (ITC) are tight clusters of GABAergic neurons, which are distributed around the basolateral amygdala complex. Distinc…
View article: Midbrain dopaminergic inputs gate amygdala intercalated cell clusters by distinct and cooperative mechanisms in male mice
Midbrain dopaminergic inputs gate amygdala intercalated cell clusters by distinct and cooperative mechanisms in male mice Open
Dopaminergic signaling plays an important role in associative learning, including fear and extinction learning. Dopaminergic midbrain neurons encode prediction error-like signals when threats differ from expectations. Within the amygdala, …
View article: Author response: Midbrain dopaminergic inputs gate amygdala intercalated cell clusters by distinct and cooperative mechanisms in male mice
Author response: Midbrain dopaminergic inputs gate amygdala intercalated cell clusters by distinct and cooperative mechanisms in male mice Open
Article Figures and data Abstract Introduction Results Discussion Materials and methods Data availability References Decision letter Author response Article and author information Metrics Abstract Dopaminergic signaling plays an important …
View article: Midbrain dopaminergic inputs gate amygdala intercalated cell clusters by distinct and cooperative mechanisms
Midbrain dopaminergic inputs gate amygdala intercalated cell clusters by distinct and cooperative mechanisms Open
A bstract Dopaminergic signaling plays an important role in associative learning including fear and extinction learning. Dopaminergic midbrain neurons encode prediction error-like signals when threats differ from expectations. Within the a…
View article: Mistletoe-Based Drugs Work in Synergy with Radio-Chemotherapy in the Treatment of Glioma<i>In Vitro</i>and<i>In Vivo</i>in Glioblastoma Bearing Mice
Mistletoe-Based Drugs Work in Synergy with Radio-Chemotherapy in the Treatment of Glioma<i>In Vitro</i>and<i>In Vivo</i>in Glioblastoma Bearing Mice Open
Background . Extracts from Viscum album L. (VE) are used in the complementary cancer therapy in Europe for decades. VE contain several compounds like the mistletoe lectins (MLs) 1-3 and viscotoxins and also several minor ingredients. Since…
View article: In Vivo Regulation of Oligodendrocyte Precursor Cell Proliferation and Differentiation by the AMPA-Receptor Subunit GluA2
In Vivo Regulation of Oligodendrocyte Precursor Cell Proliferation and Differentiation by the AMPA-Receptor Subunit GluA2 Open
The functional role of AMPA receptor (AMPAR)-mediated synaptic signaling between neurons and oligodendrocyte precursor cells (OPCs) remains enigmatic. We modified the properties of AMPARs at axon-OPC synapses in the mouse corpus callosum i…
View article: Cortical circuit activity underlying sleep slow oscillations and spindles
Cortical circuit activity underlying sleep slow oscillations and spindles Open
Significance Slow oscillations and spindles are hallmarks of the EEG during slow-wave sleep. They are thought to support memory consolidation, particularly in instances where the faster spindle nests into the “upstate” of a slow oscillatio…
View article: Environmental Enrichment Prevents Transcriptional Disturbances Induced by Alpha-Synuclein Overexpression
Environmental Enrichment Prevents Transcriptional Disturbances Induced by Alpha-Synuclein Overexpression Open
Onset and progression of neurodegenerative disorders, including synucleinopathies such as Parkinson's disease, have been associated with various environmental factors. A highly compelling association from a therapeutic point of view has be…
View article: Combined Optogenetic and Freeze-fracture Replica Immunolabeling to Examine Input-specific Arrangement of Glutamate Receptors in the Mouse Amygdala
Combined Optogenetic and Freeze-fracture Replica Immunolabeling to Examine Input-specific Arrangement of Glutamate Receptors in the Mouse Amygdala Open
Freeze-fracture electron microscopy has been a major technique in ultrastructural research for over 40 years. However, the lack of effective means to study the molecular composition of membranes produced a significant decline in its use. R…
View article: <em>Ex Vivo</em> Optogenetic Dissection of Fear Circuits in Brain Slices
<em>Ex Vivo</em> Optogenetic Dissection of Fear Circuits in Brain Slices Open
Optogenetic approaches are now widely used to study the function of neural populations and circuits by combining targeted expression of light-activated proteins and subsequent manipulation of neural activity by light. Channelrhodopsins (Ch…
View article: Postnatal maturation of GABAergic modulation of sensory inputs onto lateral amygdala principal neurons
Postnatal maturation of GABAergic modulation of sensory inputs onto lateral amygdala principal neurons Open
Key points Throughout life, fear learning is indispensable for survival and neural plasticity in the lateral amygdala underlies this learning and storage of fear memories. During development, properties of fear learning continue to change …