Ingrid Gracielle Martins da Silva
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View article: Ethanolic Extract of Pomegranate (Punica granatum L.) Prevents Oxidative Stress and Preserves the Morphology of Preantral Follicles Included in Bovine Ovarian Tissue Cultured In Vitro
Ethanolic Extract of Pomegranate (Punica granatum L.) Prevents Oxidative Stress and Preserves the Morphology of Preantral Follicles Included in Bovine Ovarian Tissue Cultured In Vitro Open
Oxidative stress compromises follicle survival during in vitro culture. Natural antioxidants may reduce cellular damage and preserve tissue integrity. This study evaluated the ethanolic extract from Punica granatum L. (EE-PG) on bovine ova…
View article: Copper Oxide Nanorods: Potential Agents against Breast Cancer
Copper Oxide Nanorods: Potential Agents against Breast Cancer Open
Breast cancer is the second most prevalent type of cancer worldwide and the leading cause of cancer-related mortality among women. Despite substantial advancements in scientific research, cancer continues to pose a major challenge due to i…
View article: Evaluation of Different Cryoprotectant Combinations in Vitrification and Slow Freezing for Ovarian Tissue Preservation in Domestic Cats
Evaluation of Different Cryoprotectant Combinations in Vitrification and Slow Freezing for Ovarian Tissue Preservation in Domestic Cats Open
Over the past decade, increased hunting and habitat disturbance have significantly impacted the endangered population within the Felidae family. Recognising this, it becomes imperative to implement strategies aimed at mitigating this conce…
View article: Green Synthesis of Silver Nanoparticles Using Paullinia cupana Kunth Leaf Extract Collected in Different Seasons: Biological Studies and Catalytic Properties
Green Synthesis of Silver Nanoparticles Using Paullinia cupana Kunth Leaf Extract Collected in Different Seasons: Biological Studies and Catalytic Properties Open
Background: Paullinia cupana Kunth, popularly known as guarana, a native Amazonian shrub cultivated by the Sateré-Mawé ethnic group, has been used in traditional medicine for various purposes, including stimulant and therapeutic actions, d…
View article: Effect of Curcumin Pretreatment on the Susceptibility of Cryptococcus neoformans to Photodynamic Therapy Mediated by Aluminum Phthalocyanine in Nanoemulsion
Effect of Curcumin Pretreatment on the Susceptibility of Cryptococcus neoformans to Photodynamic Therapy Mediated by Aluminum Phthalocyanine in Nanoemulsion Open
Background/Objectives: Curcumin has antimicrobial activity, and its mechanism of action involves changing histone acetylation. Our group has shown that histone deacetylases (HDACs) inhibitors increase the sensibility of Cryptococcus neofor…
View article: Vaccination with outer membrane vesicles from Neisseria Meningitidis and SBa15, SBa16 mesoporous silica associated with SARS-CoV-2 induces protective humoral and cellular response against COVID-19 in mice
Vaccination with outer membrane vesicles from Neisseria Meningitidis and SBa15, SBa16 mesoporous silica associated with SARS-CoV-2 induces protective humoral and cellular response against COVID-19 in mice Open
View article: Screening of novel narrow-spectrum benzofuroxan derivatives for the treatment of multidrug-resistant tuberculosis through in silico, in vitro, and in vivo approaches
Screening of novel narrow-spectrum benzofuroxan derivatives for the treatment of multidrug-resistant tuberculosis through in silico, in vitro, and in vivo approaches Open
Tuberculosis remains a serious global health threat, exacerbated by the rise of resistant strains. This study investigates the potential of two benzofuroxan ( Bfx ) derivatives, 5n and 5b, as targeted treatments for MDR-TB using in silico …
View article: Characterization of ibrutinib's effects on the morphology, proliferation, phenotype, viability, and anti-inflammatory potential of adipose-derived mesenchymal stromal cells
Characterization of ibrutinib's effects on the morphology, proliferation, phenotype, viability, and anti-inflammatory potential of adipose-derived mesenchymal stromal cells Open
Ibrutinib (IB) is a tyrosine kinase inhibitor (TKI) that has immunomodulatory action and can be used as second-line therapy for steroid-refractory or steroid-resistant chronic Graft versus Host Disease (cGVHD). Mesenchymal stromal cells (M…
View article: The Potential of Photodynamic Therapy Using Solid Lipid Nanoparticles with Aluminum Phthalocyanine Chloride as a Nanocarrier for Modulating Immunogenic Cell Death in Murine Melanoma In Vitro
The Potential of Photodynamic Therapy Using Solid Lipid Nanoparticles with Aluminum Phthalocyanine Chloride as a Nanocarrier for Modulating Immunogenic Cell Death in Murine Melanoma In Vitro Open
Photodynamic therapy (PDT) uses a photosensitizer to generate reactive oxygen species (ROS) that kill target cells. In cancer treatments, PDT can potentially induce immunogenic cell death (ICD), which is characterized by a well-controlled …
View article: Anti-Leishmania amazonensis Activity of Morolic Acid, a Pentacyclic Triterpene with Effects on Innate Immune Response during Macrophage Infection
Anti-Leishmania amazonensis Activity of Morolic Acid, a Pentacyclic Triterpene with Effects on Innate Immune Response during Macrophage Infection Open
Leishmaniasis is a group of infectious diseases transmitted to humans during vector bites and caused by protozoans of the genus Leishmania. Conventional therapies face challenges due to their serious side effects, prompting research into n…
View article: Host defense peptides combined with MTA extract increase the repair in dental pulp cells: in vitro and ex vivo study
Host defense peptides combined with MTA extract increase the repair in dental pulp cells: in vitro and ex vivo study Open
View article: Regulatory T-Cell Enhancement, Expression of Adhesion Molecules, and Production of Anti-Inflammatory Factors Are Differentially Modulated by Spheroid-Cultured Mesenchymal Stem Cells
Regulatory T-Cell Enhancement, Expression of Adhesion Molecules, and Production of Anti-Inflammatory Factors Are Differentially Modulated by Spheroid-Cultured Mesenchymal Stem Cells Open
The culture of mesenchymal stem cells (MSCs) as spheroids promotes a more physiological cellular behavior, as it more accurately reflects the biological microenvironment. Nevertheless, mixed results have been found regarding the immunosupp…
View article: Testicular characterization and spermatogenesis of the hematophagous bat Diphylla ecaudata
Testicular characterization and spermatogenesis of the hematophagous bat Diphylla ecaudata Open
Diphylla ecaudata is a hematophagous bat endemic of South America, with food preference for bird blood. Given the lack of information about the reproductive activity of this species, this study aimed to describe the testicular morphology a…
View article: Scanning Electron Microscopic/Energy-Dispersive X-Ray Analysis in Cases of Apical Periodontitis Refractory to Endodontic Treatment: A Case Series Study.
Scanning Electron Microscopic/Energy-Dispersive X-Ray Analysis in Cases of Apical Periodontitis Refractory to Endodontic Treatment: A Case Series Study. Open
This study aimed to present a case series of refractory endodontic treatment leading to persistent apical periodontitis. All cases were submitted to scanning electron microscopic/energy-dispersive X-ray analysis (SEM/EDS) of the external s…