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View article: Aetiology and Feasibility of Endoscopic Interventions for Massive Upper Gastrointestinal Bleeding in Makurdi, North-Central Nigeria
Aetiology and Feasibility of Endoscopic Interventions for Massive Upper Gastrointestinal Bleeding in Makurdi, North-Central Nigeria Open
Introduction: Massive upper gastrointestinal bleeding (UGIB) is a life-threatening emergency with high mortality. Emergency upper gastrointestinal (GI) endoscopy, endotherapy, interventional radiology, and surgery are necessary to control …
Scopolamine-induced brain injury and lipid peroxidation in Wistar rats ameliorated by garlic oil supplementation Open
Background: Scopolamine induced toxicity has been linked to impaired learning and memory, lipid peroxidation, oxidative stress and impairment of cholinergic transmission resulting in brain injury; which are synonymous with features of neur…
Ameliorative Effects of Sunflower Seeds Powder on High Fat Diet Induced Metabolic Changes in Wistar Rats Open
Background: Obesity and prediabetes are reversible disorders affecting people globally with no sex predilection. They can progress to diabetes mellitus with resultant complications. Studies have shown greater involvement of high fat diets …
Rosuvastatin ameliorates anxiety but impairs skeletal muscle performance by malondialdehyde and calcium depletion in high fat diet-fed swiss albino mice Open
Background: The high intake of high calorie, high fat diets (HFD) with an associatedsedentary lifestyle has been linked with a number of neurobehavioral and neuromusculardisorders. This study aimed at investigating the effect of a lipid lo…
Effects of vitamin E and selenium yeast on cognitive performance of pups whose dams were subjected to prenatal noise stress Open
This study investigated the effects of vitamin E and selenium yeast on the cognitive performance of pups whose dams were subjected to prenatal noise stress (PNS). Twenty-five pregnant Wistar rats were divided into five groups, group 1 (neg…
Omega 3 Fatty Acid and Cannabidiol Prolong Lifespan and Ameliorates Brain Ischaemia in Mice Fed Chronic High Fat Diet Open
Diets these days contain more fats. High fat diet (HFD) is a model of unhealthy eating in experimental animals. It is known to induce inflammatory responses and oxidative stress. Cannabidiol (CBD), the non-psychoactive component of Cannbis…
High Fat Diet Alteration of Gut Microbiota Impacts Learning, Memory and Anxiety Response in Mice: Cannabidiol and Omega 3 Possible Remedies Open
Chronic intake of High Fat Diet (HFD) has the potential of causing a number of metabolic disorders. It is also theorized to be involved in perturbation of gut microbiota. Cannabididol (CBD) and omega 3 are known to possess a number of medi…
Virgin Coconut Oil Resists Arsenic-Induced Cerebral Neurotoxicity and Cholesterol Imbalance via Suppression of Oxidative Stress, Adenosine Deaminase and Acetylcholinesterase Activities in Rats Open
Arsenic (As) is a classic neurotoxicant; its pathogenesis is associated with oxidative stress and oxidative stress-mediated cholinergic deficits. This study explored antioxidant activity of virgin coconut oil (VCO) against sodium arsenite-…
Trend of Human Immunodeficiency Virus (HIV) or Acquired Immunodeficiency Syndrome (AIDS) and Care For People Living with HIV and AIDS in Benue State, North Central, Nigeria Open
This article reveals trend of HIV/AIDS in Benue State, north central, Nigeria. The method adopted was a descriptive analysis of the HIV epidemiology in Nigeria using Benue State as a case study. This review article was through the report o…
Chronic High Fat Diet Induced Weight Gain, Hyperglycaemia and Cognitive Impairment in Albino Mice Open
With the global rise in consumption of western diet, obesity is becoming a pandemic. High fat and high calorie diet (though more palatable) have been associated with a range of metabolic disorders. Oxidative stress and insulin resistance h…
Ameliorative Effects of Virgin Coconut Oil in Loperamide Induced Constipation in rats Open
Constipation is one of the most common gastrointestinal disorders that affects people of all ages and is mostly treated using orthodox drugs that often have side effects; therefore, this research aims to investigate the effects of a natura…
ROASTED CASHEW NUT KERNEL (ANACARDIUM OCCIDENTALE L.) SUPPLEMENTATION IMPROVES HEPATIC AND RENAL STATUS BUT NOT LIPID PROFILE IN RATS Open
Objective: Although studies suggest that nut consumption is associated with a variety of beneficial health outcomes, however, there is a dearth of datain the literature to document this effect for roasted cashew nut kernel (RCNK). Our obje…