Ioannis D. Kostakis
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View article: Trajectory of frailty and association with adverse outcomes in patients with end-stage kidney disease over the first year of dialysis
Trajectory of frailty and association with adverse outcomes in patients with end-stage kidney disease over the first year of dialysis Open
View article: Author Correction: Management of patients at the hepatopancreatobiliary unit of a London teaching hospital during the COVID-19 pandemic
Author Correction: Management of patients at the hepatopancreatobiliary unit of a London teaching hospital during the COVID-19 pandemic Open
View article: Management of patients at the hepatopancreatobiliary unit of a London teaching hospital during the COVID-19 pandemic
Management of patients at the hepatopancreatobiliary unit of a London teaching hospital during the COVID-19 pandemic Open
To mitigate COVID-19-related shortage of treatment capacity, the hepatopancreatobiliary (HPB) unit of the Royal Free Hospital London (RFHL) transferred its practice to independent hospitals in Central London through the North Central Londo…
View article: Pediatric renal transplantation—A UNOS database analysis of donor–recipient size mismatch
Pediatric renal transplantation—A UNOS database analysis of donor–recipient size mismatch Open
Background We used the BSAi (Donor BSA/Recipient BSA) to assess whether transplanting a small or large kidney into a pediatric recipient relative to his/her size influences renal transplant outcomes. Methods We included 14 322 single‐kidne…
View article: Time-Related Evidence of Intestinal Oxidative Stress in Obstructive Jaundice-Induced Rats
Time-Related Evidence of Intestinal Oxidative Stress in Obstructive Jaundice-Induced Rats Open
Introduction: Obstructive jaundice is known to affect intestinal permeability and facilitate bacterial translocation through related mechanisms. This study was conducted to evaluate the alterations concerning blood biochemistry and levels …
View article: Bridging locoregional treatment prior to liver transplantation for cirrhotic patients with hepatocellular carcinoma within the Milan criteria: a systematic review and meta-analysis
Bridging locoregional treatment prior to liver transplantation for cirrhotic patients with hepatocellular carcinoma within the Milan criteria: a systematic review and meta-analysis Open
The precise benefit of bridging LRT for cirrhotic patients with HCC within the Milan criteria at diagnosis is unclear. There may be an advantage regarding short-term overall survival after liver transplantation.
View article: Adrenocortical Cancer: A 20-Year Experience of a Single Referral Center in Prognosis and Outcomes
Adrenocortical Cancer: A 20-Year Experience of a Single Referral Center in Prognosis and Outcomes Open
Adrenocortical carcinoma (ACC) is a rare but very aggressive endocrine malignancy with poor survival. Histopathology is important for diagnosis, while in some cases immunohistochemical markers and gene profiling of the resected tumor may b…
View article: MO349IMPACT OF EARLY FLUID ADMINISTRATION ON INPATIENT MORTALITY AND ACUTE KIDNEY INJURY IN PATIENTS WITH COVID-19 DISEASE
MO349IMPACT OF EARLY FLUID ADMINISTRATION ON INPATIENT MORTALITY AND ACUTE KIDNEY INJURY IN PATIENTS WITH COVID-19 DISEASE Open
Background and Aims Initial WHO guidance advised cautious fluid administration for patients with COVID-19 due to concern about the development of acute respiratory distress syndrome (ARDS). However, as the pandemic unfolded it became appar…
View article: Correction to: High fascin-1 expression in colorectal cancer identifies patients at high risk for early disease recurrence and associated mortality
Correction to: High fascin-1 expression in colorectal cancer identifies patients at high risk for early disease recurrence and associated mortality Open
View article: High fascin-1 expression in colorectal cancer identifies patients at high risk for early disease recurrence and associated mortality
High fascin-1 expression in colorectal cancer identifies patients at high risk for early disease recurrence and associated mortality Open
View article: Identifying prognostic risk factors for poor outcome following COVID-19 disease among in-centre haemodialysis patients: role of inflammation and frailty
Identifying prognostic risk factors for poor outcome following COVID-19 disease among in-centre haemodialysis patients: role of inflammation and frailty Open
View article: The role of inflammation biomarkers in differential diagnosis of pelvic tumours of ovarian origin: a single-centre observational study
The role of inflammation biomarkers in differential diagnosis of pelvic tumours of ovarian origin: a single-centre observational study Open
Inflammation biomarker ratios can easily and inexpensive assist in distinguishing malignant ovarian tumours from benign ones.
View article: P45 Preoperative D-MELD and D-UKELD scores as predictors of survival after liver transplant
P45 Preoperative D-MELD and D-UKELD scores as predictors of survival after liver transplant Open
Introduction D-MELD score, the product of donor age and preoperative MELD score, has been introduced as a potential predictive index of survival after othrotopic liver transplant (OLT). We created D-UKELD score, the product of donor age an…
View article: Hypoperfusion warm ischaemia time in renal transplants from donors after circulatory death
Hypoperfusion warm ischaemia time in renal transplants from donors after circulatory death Open
Background The donor hypoperfusion phase before asystole in renal transplants from donors after circulatory death (DCD) has been considered responsible for worse outcomes than those from donors after brain death (DBD). Methods We included …
View article: Fascin-1 expression in colorectal cancer identifies patients at high risk for early disease recurrence and associated mortality.
Fascin-1 expression in colorectal cancer identifies patients at high risk for early disease recurrence and associated mortality. Open
Background; Fascin is the main actin cross-linker protein that regulates adhesion dynamics and stabilizes cell protrusion, such as filopodia. In human cancer, fascin expression correlates with aggressive clinical features. This study aimed…
View article: Synchronous colorectal and liver resections: Safety and efficacy of the Colon-Liver-Colon operative sequence.
Synchronous colorectal and liver resections: Safety and efficacy of the Colon-Liver-Colon operative sequence. Open
View article: Nuchal-type Fibroma: Single-Center Experience and Systematic Literature Review
Nuchal-type Fibroma: Single-Center Experience and Systematic Literature Review Open
Nuchal-type fibroma should be included in the differential diagnosis of subcutaneous, soft-tissue masses, especially when these involve the posterior neck.
View article: <p>Comparison Between Robotic and Laparoscopic or Open Anastomoses: A Systematic Review and Meta-Analysis</p>
Comparison Between Robotic and Laparoscopic or Open Anastomoses: A Systematic Review and Meta-Analysis Open
Robotic anastomoses provide equal outcomes with laparoscopic and open ones in most operations, with a few notable exceptions.
View article: 368 Primary breast carcinosarcoma
368 Primary breast carcinosarcoma Open
Objectives Breast carcinosarcoma is a rare malignancy, accounting for approximately 0,08–0,2%, of all breast tumors. It consists of two cell lines, one of epithelial origin (carcinoma) and another of mesenchymal origin (sarcoma). It is a t…
View article: Comparison between liver transplantation and resection for hilar cholangiocarcinoma: A systematic review and meta-analysis
Comparison between liver transplantation and resection for hilar cholangiocarcinoma: A systematic review and meta-analysis Open
In non-disseminated unresectable tumors, LT seems to have a non-inferior survival. In the same patients, neoadjuvant chemoradiotherapy and/or strict selection criteria may contribute to superior survival outcomes compared to curative-inten…
View article: Performance of liver resections in Greece: factors that dictate postoperative ICU admission
Performance of liver resections in Greece: factors that dictate postoperative ICU admission Open
View article: Performance of liver resections in Greece: factors that dictate postoperative ICU admission
Performance of liver resections in Greece: factors that dictate postoperative ICU admission Open
View article: Laparoscopic liver resections: initial experience in Greece
Laparoscopic liver resections: initial experience in Greece Open
View article: P1.09-35 Clinical Impact of Systematic Inflammation and Histologic Grade in Non Small Cell Lung Carcinoma (NSCLC)
P1.09-35 Clinical Impact of Systematic Inflammation and Histologic Grade in Non Small Cell Lung Carcinoma (NSCLC) Open
View article: Clinical significance of RCAS1 and CD3 expression in non-small cell lung cancers in immunotherapy era
Clinical significance of RCAS1 and CD3 expression in non-small cell lung cancers in immunotherapy era Open
Background: Lung cancer is the first cause of cancer related deaths. RCAS1 (Receptor-binding Cancer Antigen expressed on SiSo cells) is a protein that is expressed in different types of cancer and seems to be involved in the process of the…
View article: White blood cell and platelet indices as indicators of pancreatic tumor type and disease stage
White blood cell and platelet indices as indicators of pancreatic tumor type and disease stage Open
View article: Transperitoneal <i>Versus</i> Extraperitoneal Laparoscopic Lymphadenectomy for Gynecological Malignancies: A Systematic Review and Meta-analysis
Transperitoneal <i>Versus</i> Extraperitoneal Laparoscopic Lymphadenectomy for Gynecological Malignancies: A Systematic Review and Meta-analysis Open
ELL is safe and efficient with outcomes comparable to TLL in terms of lymph node yield and improved operative outcomes with regard to lymphadenectomy times and intraoperative complications.
View article: Canagliflozin attenuates the progression of atherosclerosis and inflammation process in APOE knockout mice
Canagliflozin attenuates the progression of atherosclerosis and inflammation process in APOE knockout mice Open
Canagliflozin attenuates the progression of atherosclerosis, reducing (1) hyperlipidemia and hyperglycemia, and (2) inflammatory process, by lowering the expression of inflammatory molecules such as MCP-1 and VCAM-1. Moreover, canagliflozi…
View article: Malignant potential of epithelioid angiomyolipomas of the liver: A case report and comprehensive review of the literature
Malignant potential of epithelioid angiomyolipomas of the liver: A case report and comprehensive review of the literature Open
Hepatic epithelioid angiomyolipoma (HEAML) is a rare mesenchymal tumor that has been reported to have malignant potential. We herein describe a rare case of atypical HEAML. A 43-year-old Caucasian male patient visited his general practitio…