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View article: New Insights in Microcirculation Research in Sepsis
New Insights in Microcirculation Research in Sepsis Open
Sepsis remains a leading cause of morbidity and mortality worldwide, with certain high-risk populations—including elderly patients, neonates, immunocompromised individuals, those with chronic diseases, and pregnant women—experiencing worse…
View article: Long-Term Survival in Metachronous Primary Malignancies: Stage III Nasopharyngeal Cancer and Stage IV Non-Small-Cell Lung Cancer
Long-Term Survival in Metachronous Primary Malignancies: Stage III Nasopharyngeal Cancer and Stage IV Non-Small-Cell Lung Cancer Open
Introduction: The occurrence of a second primary lung cancer after head and neck cancer is a challenge for multidisciplinary teams, since the development of a second lung cancer negatively affects the survival rate of patients with head an…
View article: Vulvar Metastasis in Renal Cell Carcinoma: A Case Report Highlighting the Aggressive Nature of Clear Cell Renal Cell Carcinoma
Vulvar Metastasis in Renal Cell Carcinoma: A Case Report Highlighting the Aggressive Nature of Clear Cell Renal Cell Carcinoma Open
Vulvar cancer is one of the rarest gynecological malignancies. The development of this condition can be associated with either dysplasia linked to human papillomavirus (HPV), primarily affecting younger women, or vulvar dermatoses such as …
View article: Gastrointestinal stromal tumors: a focus on the impact of interstitial cells of Cajal in disease development
Gastrointestinal stromal tumors: a focus on the impact of interstitial cells of Cajal in disease development Open
Introduction. Interstitial Cells of Cajal (ICCs) play a critical role in the regulation of gastrointestinal motility and have been implicated in various functional gastrointestinal disorders. Recent research indicates a possible associatio…
View article: Long-Term Survival in Metastatic Pancreatic Adenocarcinoma of Intestinal Type
Long-Term Survival in Metastatic Pancreatic Adenocarcinoma of Intestinal Type Open
Introduction and Literature Review: Pancreatic cancer is often diagnosed in an advanced/metastatic stage, as it is a very aggressive type of cancer. The prognosis of pancreatic cancer is extremely unfavorable. The mean survival rate for pa…
View article: Reinitiating Chemotherapy beyond Progression after Maintenance Immunotherapy in Extensive-Stage Small-Cell Lung Cancer
Reinitiating Chemotherapy beyond Progression after Maintenance Immunotherapy in Extensive-Stage Small-Cell Lung Cancer Open
Introduction: Small-cell lung cancer (SCLC) is an aggressive form of cancer with a poor prognosis. The two-year survival rate is 8% of all cases. Case presentation: We present the case of a male patient who was 50 years old at the time of …
View article: Emergency and Elective Colorectal Cancer—Relationship between Clinical Factors, Tumor Topography and Surgical Strategies: A Cohort Study
Emergency and Elective Colorectal Cancer—Relationship between Clinical Factors, Tumor Topography and Surgical Strategies: A Cohort Study Open
Background and Objectives: The purpose of the study was to analyze the relationships among several clinical factors and also the tumor topography and surgical strategies used in patients with colorectal cancer. Materials and Methods: We de…
View article: The Impact of Cancer Stem Cells in Colorectal Cancer
The Impact of Cancer Stem Cells in Colorectal Cancer Open
Despite incessant research, colorectal cancer (CRC) is still one of the most common causes of fatality in both men and women worldwide. Over time, advancements in medical treatments have notably enhanced the survival rates of patients with…
View article: Emergency and Elective Colorectal Cancer – Relationship between Clinical and Biological Factors, Tumor Topography and Surgical Strategies. A Cohort Study
Emergency and Elective Colorectal Cancer – Relationship between Clinical and Biological Factors, Tumor Topography and Surgical Strategies. A Cohort Study Open
Background and Objectives: The purpose of the study was to analyze the relationships between several clinical and biological factors, but also the tumor topography and surgical strategies used in patients with colorectal cancer. Materials …
View article: Alternative surgical techniques in the treatment of hydrocephalus
Alternative surgical techniques in the treatment of hydrocephalus Open
Hydrocephaly, or hydrocephalus, is a pathological condition characterized by an excessive Cerebrospinal Fluid (CSF) accumulation within the cerebral ventricular system that leads to intracranial hypertension. This elevated pressure, known …
View article: Spindle Cell Rhabdomyosarcoma of the Inguinal Region Mimicking a Complicated Hernia in the Adult—An Unexpected Finding
Spindle Cell Rhabdomyosarcoma of the Inguinal Region Mimicking a Complicated Hernia in the Adult—An Unexpected Finding Open
Rhabdomyosarcoma is a rare tumor that is diagnosed mostly in children and adolescents, rarely in adults, representing 2–5% of all soft tissue sarcomas. It has four subtypes that are recognized: embryonal (50%), alveolar (20%), pleomorphic …
View article: Right Transcephalic Ventriculo-Subclavian Shunt in the Surgical Treatment of Hydrocephalus—An Original Procedure for Drainage of Cerebrospinal Fluid into the Venous System
Right Transcephalic Ventriculo-Subclavian Shunt in the Surgical Treatment of Hydrocephalus—An Original Procedure for Drainage of Cerebrospinal Fluid into the Venous System Open
The objectives of this article are to present an original surgical procedure for the temporary or definitive resolution of hydrocephalus, in the case of repeated failure of standard treatment techniques, and to present a case that was reso…
View article: Colorectal Cancer—The “Parent” of Low Bowel Obstruction
Colorectal Cancer—The “Parent” of Low Bowel Obstruction Open
Introduction: Despite the improvement of early diagnosis methods for multiple pathological entities belonging to the digestive tract, bowel obstruction determined by multiple etiologies represents an important percentage of surgical emerge…
View article: Meropenem antibiotic therapy in acute secondary peritonitis, therapeutic effects superior to other therapies – experimental clinical and histopathological study in the laboratory animal
Meropenem antibiotic therapy in acute secondary peritonitis, therapeutic effects superior to other therapies – experimental clinical and histopathological study in the laboratory animal Open
Antibiotic therapy with Meropenem in acute peritonitis has a survival rate comparable to peritoneal lavage and source control.
View article: Incidental case of primary renal lymphoma (PRL) in a patient with chronic hepatitis C infection. Report of a rare case
Incidental case of primary renal lymphoma (PRL) in a patient with chronic hepatitis C infection. Report of a rare case Open
Chronic viral hepatitis C (CHC) is a global health problem, being responsible for about 399 000 deaths worldwide, mostly from cirrhosis and hepatocellular carcinoma. Virus C infection has well known hepatic manifestations - cirrhosis and l…
View article: Diagnostic and Therapeutic Particularities in Abdominal Trauma Associated with Spinal Cord Injuries - Review of the Literature
Diagnostic and Therapeutic Particularities in Abdominal Trauma Associated with Spinal Cord Injuries - Review of the Literature Open
Post-traumatic morbid associations may evolve by themselves, or can interact, with effects of adding or potentiating gravity. Sometimes cumulative or potentiating effects are associated with clinical and paraclinical confusing manifestatio…
View article: Clinical Features and Therapeutic Management of Postoperative Eso-Gastro-Duodenal Fistulas – A 6-Year Retrospective Study
Clinical Features and Therapeutic Management of Postoperative Eso-Gastro-Duodenal Fistulas – A 6-Year Retrospective Study Open
The postoperative digestive fistula is the most feared complication of gastrointestinal surgeries. We performed a retrospective study over a period of 6 years, in which we included 28 patients who developed postoperative esophageal, gastri…
View article: Traumatic Diaphragmatic Lesions - Considerations Over a Series of 15 Consecutive Cases
Traumatic Diaphragmatic Lesions - Considerations Over a Series of 15 Consecutive Cases Open
Introduction: Diaphragmatic injuries are produced by blunt or penetrating thoracoabdominal trauma. They are potentially life-threatening due to the herniation of abdominal organs into the pleural cavities and severe associated lesions. The…
View article: Retained Common Bile Duct Lithiasis at a Pacient with Periampullary Duodenal Diverticulum
Retained Common Bile Duct Lithiasis at a Pacient with Periampullary Duodenal Diverticulum Open
Periampullary duodenal diverticula are associated with the presence of common bile duct stones, being encountered more frequently with the increase of age. We present the case of a 76 years old female patient, who underwents emergency surg…