Wuyang Huang
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View article: Phenolic Extracts of Hulless Barley Grass Alleviate Progression of Colitis‐Related Colorectal Cancer by Inhibiting the Overexpression of Wnt/β‐Catenin Signaling Pathway
Phenolic Extracts of Hulless Barley Grass Alleviate Progression of Colitis‐Related Colorectal Cancer by Inhibiting the Overexpression of Wnt/β‐Catenin Signaling Pathway Open
Ulcerative colitis (UC), a precursor of colorectal cancer (CRC) driven by Wnt/β‐Catenin pathway activation, may be mitigated by hulless barley grass (HBG), a high‐altitude crop with antioxidant, anti‐inflammatory, and anti‐tumor effects. A…
View article: Extracellular vesicle-derived microRNAs in renal cell carcinoma: biological roles and clinical applications
Extracellular vesicle-derived microRNAs in renal cell carcinoma: biological roles and clinical applications Open
Renal cell carcinoma (RCC) is a common malignant tumour of the urinary system, characterised by high heterogeneity and a tendency to metastasise, with poor prognosis in advanced patients. Although surgical resection and targeted therapies …
View article: Social participation and insomnia in Chinese older adults with multimorbidity: mediating roles of frailty, anxiety, and depression
Social participation and insomnia in Chinese older adults with multimorbidity: mediating roles of frailty, anxiety, and depression Open
Based on the stress process theory, our study showed that frailty, anxiety and depression serially mediated the relationship between social participation and insomnia. These findings hold significant practical implications and suggest that…
View article: Effects of Burdock Addition and Different Starters on the Quality and Flavor Improvement of Duck Sausages
Effects of Burdock Addition and Different Starters on the Quality and Flavor Improvement of Duck Sausages Open
Burdock (Arctium lappa L.) is a medicinal and edible homologous plant whose roots contain many bioactive substances such as polysaccharides and phenolics. This study explored the integration of burdock powder and lactic acid bacteria ferme…
View article: Phytochemical Profiling, Antioxidant Capacity, and α-Amylase/α-Glucosidase Inhibitory Effects of 29 Faba Bean (Vicia faba L.) Varieties from China
Phytochemical Profiling, Antioxidant Capacity, and α-Amylase/α-Glucosidase Inhibitory Effects of 29 Faba Bean (Vicia faba L.) Varieties from China Open
Faba bean (Vicia faba L.), a nutrient-rich legume beneficial to human health, is valued for its high L-3,4-dihydroxyphenylalanine (L-DOPA) and phenolic content. This study investigated phytochemical diversity and bioactivity across 29 Chin…
View article: High-Pressure Microfluidic Homogenization Improves the Stability and Antioxidant Properties of Coenzyme Q10 Nanoliposomes
High-Pressure Microfluidic Homogenization Improves the Stability and Antioxidant Properties of Coenzyme Q10 Nanoliposomes Open
Coenzyme Q10 is a natural antioxidant with anti-tumor and mitochondrial protective effects. However, its unstable physicochemical properties and large molecular weight result in low bioavailability. This study aimed to develop an effective…
View article: Optimization of Ultrasonic-Enzymatic-Assisted Extraction of Flavonoids from Sea Buckthorn (Hippophae rhamnoides L.) Pomace: Chemical Composition and Biological Activities
Optimization of Ultrasonic-Enzymatic-Assisted Extraction of Flavonoids from Sea Buckthorn (Hippophae rhamnoides L.) Pomace: Chemical Composition and Biological Activities Open
Sea buckthorn pomace (SBP) is a rich source of flavonoid compounds with potential healthy properties. This study optimized ultrasonic-enzymatic-assisted extraction (UEAE) of flavonoids from SBP and investigated its chemical composition and…
View article: Effect of Chinese bayberry residue on quality of Chinese quinoa (Chenopodium quinoa Willd.) Rice wine
Effect of Chinese bayberry residue on quality of Chinese quinoa (Chenopodium quinoa Willd.) Rice wine Open
Chinese bayberry residue (CBR) is a by-product of processing, which can be used as an auxiliary material during the processing of quinoa rice wine. In this study, the effects of CBR on the chemical profile, bioactive function, taste traits…
View article: Inhibition of Hyperglycemia and Hyperlipidemia by Blocking Toll-like Receptor 4: Comparison of Wild-Type and Toll-like Receptor 4 Gene Knockout Mice on Obesity and Diabetes Modeling
Inhibition of Hyperglycemia and Hyperlipidemia by Blocking Toll-like Receptor 4: Comparison of Wild-Type and Toll-like Receptor 4 Gene Knockout Mice on Obesity and Diabetes Modeling Open
Innate immune receptor TLR4 plays an important role in glycolipid metabolism. The objective of this study is to investigate the inhibitory effects of blocking TLR4 on hyperglycemia and hyperlipidemia by comparing WT and TLR4−/− mice in obe…
View article: Chlorogenic Acid from Burdock Roots Ameliorates Oleic Acid-Induced Steatosis in HepG2 Cells through AMPK/ACC/CPT-1 Pathway
Chlorogenic Acid from Burdock Roots Ameliorates Oleic Acid-Induced Steatosis in HepG2 Cells through AMPK/ACC/CPT-1 Pathway Open
Hepatic steatosis can cause liver dysfunction and cell injury, on which natural functional factors are expected to be an effective approach for long-term intervention. However, the cellular molecular mechanisms are unclear. Chlorogenic aci…
View article: Icariin attenuates the calcification of vascular smooth muscle cells through <scp>ERα</scp> – <scp>p38MAPK</scp> pathway
Icariin attenuates the calcification of vascular smooth muscle cells through <span>ERα</span> – <span>p38MAPK</span> pathway Open
Objective To investigate the relationship between icariin and the osteoblastic differentiation of vascular smooth muscle cells (VSMCs) and the signal pathway involved. Methods We applied a universally accepted calcification model of VSMCs …
View article: Improving Blueberry Anthocyanins’ Stability Using a Ferritin Nanocarrier
Improving Blueberry Anthocyanins’ Stability Using a Ferritin Nanocarrier Open
Blueberries are fruits known for their high level of anthocyanins, which have high nutritional value and several biological properties. However, the chemical instability of anthocyanins is one of the major limitations of their application.…
View article: Effects of four drying methods on the quality, antioxidant activity and anthocyanin components of blueberry pomace
Effects of four drying methods on the quality, antioxidant activity and anthocyanin components of blueberry pomace Open
The effects of drying on the quality, antioxidant activity and anthocyanin components of blueberry pomace were investigated using hot air drying (HAD), freeze-drying (FD), microwave vacuum drying (MVD) and microwave freeze vacuum drying (M…
View article: Methods of postoperative void trial management after urogynecologic surgery: a systematic review and meta-analysis
Methods of postoperative void trial management after urogynecologic surgery: a systematic review and meta-analysis Open
Background Voiding trials are used to identify women at risk for postoperative urinary retention while performing optimal voiding trial management with minimal burden to the patient and medical service team. We performed a systematic revie…
View article: In vivo antioxidant activity of rabbiteye blueberry (Vaccinium ashei cv. ‘Brightwell’) anthocyanin extracts
In vivo antioxidant activity of rabbiteye blueberry (Vaccinium ashei cv. ‘Brightwell’) anthocyanin extracts Open
Blueberries are rich in phenolic compounds including anthocyanins which are closely related to biological health functions. The purpose of this study was to investigate the antioxidant activity of blueberry anthocyanins extracted from 'Bri…
View article: Editorial: Advances in anthocyanins: Sources, preparation, analysis methods, bioavailability, physiochemical properties, and structural features
Editorial: Advances in anthocyanins: Sources, preparation, analysis methods, bioavailability, physiochemical properties, and structural features Open
EDITORIAL article Front. Nutr., 16 February 2023Sec. Food Chemistry Volume 10 - 2023 | https://doi.org/10.3389/fnut.2023.1148051
View article: Supplementary Material for: Red Blood Cell Membrane-Related Gene Variants and Clinical Risk Factors in Chinese Neonates with Hyperbilirubinemia
Supplementary Material for: Red Blood Cell Membrane-Related Gene Variants and Clinical Risk Factors in Chinese Neonates with Hyperbilirubinemia Open
Introduction: Neonatal hyperbilirubinemia is common and remains a clinical concern in China. Since neonatal hyperbilirubinemia is linked to genetic factors, we aimed to identify the gene variants of the red blood cell membrane (RBCM) and e…
View article: Optimization of Ultra-high Pressure Extraction and the Antioxidant Activity of Anthocyanins from Blueberry Pomace
Optimization of Ultra-high Pressure Extraction and the Antioxidant Activity of Anthocyanins from Blueberry Pomace Open
The objective of this study was to optimize the ultra-high pressure extraction (UPE) process of anthocyanins extracted from blueberry pomace and to investigate the antioxidant activity of the anthocyanin extracts. In the present study, the…
View article: Long noncoding RNA SNHG1 alleviates high glucose-induced vascular smooth muscle cells calcification/senescence by post-transcriptionally regulating Bhlhe40 and autophagy via Atg10
Long noncoding RNA SNHG1 alleviates high glucose-induced vascular smooth muscle cells calcification/senescence by post-transcriptionally regulating Bhlhe40 and autophagy via Atg10 Open
Long noncoding RNAs (lncRNAs) are emerging regulators of vascular diseases, yet their role in diabetic vascular calcification/aging remains poorly understood. In this study, we identified a down-expressed lncRNA SNHG1 in high glucose (HG)-…