Irina Bacila
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View article: Leptin and adiponectin in children and young persons with congenital adrenal hyperplasia
Leptin and adiponectin in children and young persons with congenital adrenal hyperplasia Open
Objectives Patients with congenital adrenal hyperplasia (CAH) have increased prevalence of metabolic problems. We studied adiponectin, leptin and resistin in children with CAH, in relation to BMI, treatment, hormonal and metabolic biomarke…
View article: Blood pressure and its associations in 554 children and young people with congenital adrenal hyperplasia
Blood pressure and its associations in 554 children and young people with congenital adrenal hyperplasia Open
Background Congenital adrenal hyperplasia (CAH) due to 21-hydroxylase deficiency (21OHD) affects approximately 1 in 15 000 individuals. We leveraged the power of multicentre registry data to assess the trend and predictors of blood pressur…
View article: Risk of Bias in Machine Learning and Statistical Models to Predict Height or Weight: A Systematic Review in Fetal and Paediatric Medicine
Risk of Bias in Machine Learning and Statistical Models to Predict Height or Weight: A Systematic Review in Fetal and Paediatric Medicine Open
View article: Health status of children and young persons with congenital adrenal hyperplasia in the UK (CAH-UK): a cross-sectional multi-centre study
Health status of children and young persons with congenital adrenal hyperplasia in the UK (CAH-UK): a cross-sectional multi-centre study Open
Objective There is limited knowledge on the onset of comorbidities in congenital adrenal hyperplasia (CAH) during childhood. We aimed to establish the health status of children with CAH in the UK. Design and methods This cross-sectional mu…
View article: International practice of corticosteroid replacement therapy in congenital adrenal hyperplasia: data from the I-CAH registry
International practice of corticosteroid replacement therapy in congenital adrenal hyperplasia: data from the I-CAH registry Open
Objective Despite published guidelines no unified approach to hormone replacement in congenital adrenal hyperplasia (CAH) exists. We aimed to explore geographical and temporal variations in the treatment with glucocorticoids and mineraloco…
View article: Measurement of Salivary Adrenal-Specific Androgens as Biomarkers of Therapy Control in 21-Hydroxylase Deficiency
Measurement of Salivary Adrenal-Specific Androgens as Biomarkers of Therapy Control in 21-Hydroxylase Deficiency Open
Background Monitoring of hormonal control represents a key part of the management of congenital adrenal hyperplasia (CAH). Monitoring strategies remain suboptimal because they rely on frequent blood tests and are not specific for adrenal-d…