Iris Breitkreutz
YOU?
Author Swipe
View article: EASIX-guided risk stratification for complications and outcome after CAR T-cell therapy with ide-cel in relapsed/refractory multiple myeloma
EASIX-guided risk stratification for complications and outcome after CAR T-cell therapy with ide-cel in relapsed/refractory multiple myeloma Open
Background Chimeric antigen receptor (CAR) T-cell therapy has demonstrated significant benefits in the treatment of relapsed/refractory multiple myeloma (RRMM). However, these outcomes can be compromised by severe complications, including …
View article: Longitudinal assessment of established risk stratification models in patients with monoclonal gammopathy of undetermined significance
Longitudinal assessment of established risk stratification models in patients with monoclonal gammopathy of undetermined significance Open
Risk of progression of monoclonal gammopathy of undetermined significance (MGUS) into multiple myeloma and related plasma cell disorders can be determined by three major risk stratification models, namely Mayo2005, Sweden2014, and NCI2019.…
View article: Supplementary Figure 1 from GF-15, a Novel Inhibitor of Centrosomal Clustering, Suppresses Tumor Cell Growth <i>In Vitro</i> and <i>In Vivo</i>
Supplementary Figure 1 from GF-15, a Novel Inhibitor of Centrosomal Clustering, Suppresses Tumor Cell Growth <i>In Vitro</i> and <i>In Vivo</i> Open
PDF file - 60K, GF-15 does not induce spindle multipolarity in resistant cells
View article: Supplementary Figure Legends 1-5 from GF-15, a Novel Inhibitor of Centrosomal Clustering, Suppresses Tumor Cell Growth <i>In Vitro</i> and <i>In Vivo</i>
Supplementary Figure Legends 1-5 from GF-15, a Novel Inhibitor of Centrosomal Clustering, Suppresses Tumor Cell Growth <i>In Vitro</i> and <i>In Vivo</i> Open
PDF file - 50K
View article: Supplementary Figure Legends 1-5 from GF-15, a Novel Inhibitor of Centrosomal Clustering, Suppresses Tumor Cell Growth <i>In Vitro</i> and <i>In Vivo</i>
Supplementary Figure Legends 1-5 from GF-15, a Novel Inhibitor of Centrosomal Clustering, Suppresses Tumor Cell Growth <i>In Vitro</i> and <i>In Vivo</i> Open
PDF file - 50K
View article: Supplementary Figure 4 from GF-15, a Novel Inhibitor of Centrosomal Clustering, Suppresses Tumor Cell Growth <i>In Vitro</i> and <i>In Vivo</i>
Supplementary Figure 4 from GF-15, a Novel Inhibitor of Centrosomal Clustering, Suppresses Tumor Cell Growth <i>In Vitro</i> and <i>In Vivo</i> Open
PDF file - 69K, GF-15 decreases tumor growth in a HT29 xenograft mouse model
View article: Data from GF-15, a Novel Inhibitor of Centrosomal Clustering, Suppresses Tumor Cell Growth <i>In Vitro</i> and <i>In Vivo</i>
Data from GF-15, a Novel Inhibitor of Centrosomal Clustering, Suppresses Tumor Cell Growth <i>In Vitro</i> and <i>In Vivo</i> Open
In contrast to normal cells, malignant cells are frequently aneuploid and contain multiple centrosomes. To allow for bipolar mitotic division, supernumerary centrosomes are clustered into two functional spindle poles in many cancer cells. …
View article: Supplementary Figure 5 from GF-15, a Novel Inhibitor of Centrosomal Clustering, Suppresses Tumor Cell Growth <i>In Vitro</i> and <i>In Vivo</i>
Supplementary Figure 5 from GF-15, a Novel Inhibitor of Centrosomal Clustering, Suppresses Tumor Cell Growth <i>In Vitro</i> and <i>In Vivo</i> Open
PDF file - 51K, GF-15 significantly increases the mitotic index in MM xenograft tumors
View article: Supplementary Figure 1 from GF-15, a Novel Inhibitor of Centrosomal Clustering, Suppresses Tumor Cell Growth <i>In Vitro</i> and <i>In Vivo</i>
Supplementary Figure 1 from GF-15, a Novel Inhibitor of Centrosomal Clustering, Suppresses Tumor Cell Growth <i>In Vitro</i> and <i>In Vivo</i> Open
PDF file - 60K, GF-15 does not induce spindle multipolarity in resistant cells
View article: Supplementary Figure 3 from GF-15, a Novel Inhibitor of Centrosomal Clustering, Suppresses Tumor Cell Growth <i>In Vitro</i> and <i>In Vivo</i>
Supplementary Figure 3 from GF-15, a Novel Inhibitor of Centrosomal Clustering, Suppresses Tumor Cell Growth <i>In Vitro</i> and <i>In Vivo</i> Open
PDF file - 81K, HeLa-PLK4 cells treated with GF-15
View article: Data from GF-15, a Novel Inhibitor of Centrosomal Clustering, Suppresses Tumor Cell Growth <i>In Vitro</i> and <i>In Vivo</i>
Data from GF-15, a Novel Inhibitor of Centrosomal Clustering, Suppresses Tumor Cell Growth <i>In Vitro</i> and <i>In Vivo</i> Open
In contrast to normal cells, malignant cells are frequently aneuploid and contain multiple centrosomes. To allow for bipolar mitotic division, supernumerary centrosomes are clustered into two functional spindle poles in many cancer cells. …
View article: Supplementary Figure 3 from GF-15, a Novel Inhibitor of Centrosomal Clustering, Suppresses Tumor Cell Growth <i>In Vitro</i> and <i>In Vivo</i>
Supplementary Figure 3 from GF-15, a Novel Inhibitor of Centrosomal Clustering, Suppresses Tumor Cell Growth <i>In Vitro</i> and <i>In Vivo</i> Open
PDF file - 81K, HeLa-PLK4 cells treated with GF-15
View article: Supplementary Figure 2 from GF-15, a Novel Inhibitor of Centrosomal Clustering, Suppresses Tumor Cell Growth <i>In Vitro</i> and <i>In Vivo</i>
Supplementary Figure 2 from GF-15, a Novel Inhibitor of Centrosomal Clustering, Suppresses Tumor Cell Growth <i>In Vitro</i> and <i>In Vivo</i> Open
PDF file - 239K, HeLa-PLK4 cells display centrosome amplification
View article: Supplementary Figure 5 from GF-15, a Novel Inhibitor of Centrosomal Clustering, Suppresses Tumor Cell Growth <i>In Vitro</i> and <i>In Vivo</i>
Supplementary Figure 5 from GF-15, a Novel Inhibitor of Centrosomal Clustering, Suppresses Tumor Cell Growth <i>In Vitro</i> and <i>In Vivo</i> Open
PDF file - 51K, GF-15 significantly increases the mitotic index in MM xenograft tumors
View article: Supplementary Figure 2 from GF-15, a Novel Inhibitor of Centrosomal Clustering, Suppresses Tumor Cell Growth <i>In Vitro</i> and <i>In Vivo</i>
Supplementary Figure 2 from GF-15, a Novel Inhibitor of Centrosomal Clustering, Suppresses Tumor Cell Growth <i>In Vitro</i> and <i>In Vivo</i> Open
PDF file - 239K, HeLa-PLK4 cells display centrosome amplification
View article: Supplementary Figure 4 from GF-15, a Novel Inhibitor of Centrosomal Clustering, Suppresses Tumor Cell Growth <i>In Vitro</i> and <i>In Vivo</i>
Supplementary Figure 4 from GF-15, a Novel Inhibitor of Centrosomal Clustering, Suppresses Tumor Cell Growth <i>In Vitro</i> and <i>In Vivo</i> Open
PDF file - 69K, GF-15 decreases tumor growth in a HT29 xenograft mouse model
View article: Concurrent light chain amyloidosis and proximal tubulopathy: Insights into different aggregation behavior—A case report
Concurrent light chain amyloidosis and proximal tubulopathy: Insights into different aggregation behavior—A case report Open
Due to differences in the protein folding mechanisms, it is exceedingly rare for amyloid light chain (AL) amyloidosis and monoclonal gammopathy of renal significance (MGRS) to coexist. We herein report the first case of concurrent AL amylo…
View article: Carfilzomib, Lenalidomide, and Dexamethasone Followed by Salvage Autologous Stem Cell Transplant with or without Maintenance for Relapsed or Refractory Multiple Myeloma
Carfilzomib, Lenalidomide, and Dexamethasone Followed by Salvage Autologous Stem Cell Transplant with or without Maintenance for Relapsed or Refractory Multiple Myeloma Open
Salvage high-dose chemotherapy and autologous stem cell transplantation (HDCT/ASCT) is a treatment option for relapsed and/or refractory multiple myeloma (RRMM). No data are available on salvage HDCT/ASCT following re-induction treatment w…