Irkham Irkham
YOU?
Author Swipe
View article: Porcine gelatine detection <i>via </i>electrochemical immunosensors utilizing green-synthesized cerium oxide nanoparticles from orange peel
Porcine gelatine detection <i>via </i>electrochemical immunosensors utilizing green-synthesized cerium oxide nanoparticles from orange peel Open
Maintaining the safety and proper labelling of food products is vital for communities around the world. One of the primary concerns in food safety is the unintentional presence of porcine derivatives such as gelatine in food products. This…
View article: Monolayer graphene/platinum-modified 3D origami microfluidic paper-based biosensor for smartphone-assisted biomarkers detection
Monolayer graphene/platinum-modified 3D origami microfluidic paper-based biosensor for smartphone-assisted biomarkers detection Open
Background and purpose: Imbalances in biomarkers such as dopamine and NADH are linked to neurological and metabolic disorders, including Parkinson’s disease, depression, and stroke, underscoring the need for rapid and accessible diagnostic…
View article: CRISPR-Cas13a-powered electrochemical biosensors for RNA-based disease diagnostic and monitoring
CRISPR-Cas13a-powered electrochemical biosensors for RNA-based disease diagnostic and monitoring Open
Nucleic acids serve as specific, selective, and sensitive components in molecular diagnostics, offering efficient and high-precision results. Unlike DNA, RNA expression reflects real-time cellular activity, allowing for the monitoring of d…
View article: Platinum-modified screen-printed carbon electrode integrated with molecularly imprinted polymer for highly selective electrochemical ethanol sensing
Platinum-modified screen-printed carbon electrode integrated with molecularly imprinted polymer for highly selective electrochemical ethanol sensing Open
Ethanol is a type of alcohol often found in beverages, medicines, and fermented products, so an acceptable ethanol detection method is needed. An accurate ethanol detection method is the chromatography method, but its weaknesses are high o…
View article: Boron-doped diamond electrodes for electrochemical glucose detection via enzymatic and non-enzymatic approaches
Boron-doped diamond electrodes for electrochemical glucose detection via enzymatic and non-enzymatic approaches Open
The development of highly sensitive and reliable glucose sensors has driven significant interest in boron-doped diamond (BDD) electrodes due to their exceptional electrochemical properties. With superior chemical stability, a wide potentia…
View article: CRISPR-Cas9-based electrochemical biosensor for the detection of <i>katG</i> gene mutations in isoniazid-resistant tuberculosis
CRISPR-Cas9-based electrochemical biosensor for the detection of <i>katG</i> gene mutations in isoniazid-resistant tuberculosis Open
Background and purpose: Multidrug-resistant tuberculosis (MDR-TB) remains a significant challenge in tuberculosis (TB) treatment, driven by simultaneous mutations in the rpoB and katG genes that confer resistance to rifampicin and isoniazi…
View article: Correlation between A3243G and G9053A mtDNA mutations and ATP levels in diabetes mellitus patients using qPCR and electrochemical aptasensors
Correlation between A3243G and G9053A mtDNA mutations and ATP levels in diabetes mellitus patients using qPCR and electrochemical aptasensors Open
Background and purpose: Mitochondrial DNA (mtDNA) mutations can impair oxidative phosphorylation and ATP production, potentially contributing to the pathogenesis of type 2 diabetes mellitus (T2DM). This study aimed to investigate the relat…
View article: Label-free electrochemical immunosensor for porcine gelatin using a boron-doped diamond electrode <i>via</i> diazonium salt electrografting
Label-free electrochemical immunosensor for porcine gelatin using a boron-doped diamond electrode <i>via</i> diazonium salt electrografting Open
Porcine gelatin is widely used in the food and pharmaceutical industries due to its favorable functional properties and low cost. However, its presence in consumer products raises serious concerns for individuals with dietary restrictions …
View article: Electrochemical Sensor and Biosensor Detection of Ethanol in Beverage Samples
Electrochemical Sensor and Biosensor Detection of Ethanol in Beverage Samples Open
Ethanol detection is critical in the beverage industry, where it is essential to monitor alcohol concentrations for quality control and compliance with regulatory standards. Traditional analytical methods, such as gas chromatography and di…
View article: Advanced aptamer-based sensors for monitoring theophylline
Advanced aptamer-based sensors for monitoring theophylline Open
Theophylline is a widely used bronchodilator for treating asthma-related symptoms like shortness of breath and chest tightness. However, its narrow therapeutic plasma range (20-200 μM) necessitates careful monitoring of blood levels to pre…
View article: Gold nanoparticle-modified screen-printed carbon electrodes for label-free detection of SARS-CoV-2 RNA using drop casting and spray coating methods
Gold nanoparticle-modified screen-printed carbon electrodes for label-free detection of SARS-CoV-2 RNA using drop casting and spray coating methods Open
Background and purpose: This study aimed to explore the modification of screen-printed carbon electrode (SPCE) to produce an extensive conductive surface with gold nanoparticles (AuNPs) for the detection of Severe acute respiratory syndrom…
View article: A novel strategy of water-based synthesis method of zeolitic-imidazolate framework-14 (ZIF-14)
A novel strategy of water-based synthesis method of zeolitic-imidazolate framework-14 (ZIF-14) Open
This study report outlines a water-based rapid method for synthesizing zeolitic-imidazolate framework-14 (ZIF-14) at room temperature. ZIF-14 crystals were prepared by the reaction of 2-eim, zinc nitrate, and cetyltrimethylammonium bromide…
View article: Electrochemical aptasensor for ultrasensitive detection of glycated hemoglobin (HbA1c) using gold-modified SPCE
Electrochemical aptasensor for ultrasensitive detection of glycated hemoglobin (HbA1c) using gold-modified SPCE Open
Accurate monitoring of diabetes mellitus (DM) biomarkers, particularly glycated hemoglobin (HbA1c), is essential for assessing long-term blood glucose control, optimizing therapeutic strategies, and preventing diabetes-related complication…
View article: A CRISPR/Cas12a electrochemical biosensing to detect pig mtDNA D-loop for ensuring food authenticity
A CRISPR/Cas12a electrochemical biosensing to detect pig mtDNA D-loop for ensuring food authenticity Open
Ensuring safe and accurately labeled food products is crucial for communities worldwide. One significant concern in food safety is the unintended inclusion of pork in products, which impacts food labeling, religious dietary practices, lega…
View article: Doping of rare earth element: The effects in elevated physical and optical properties of ZnO
Doping of rare earth element: The effects in elevated physical and optical properties of ZnO Open
Zinc oxide (ZnO) serves as a highly adaptable semiconductor with a crucial role in various applications because of its crystal structure compatibility and significant band gap. Fabricating ZnO nanomaterials with tailored characteristics ha…
View article: Advancements in synthesis of Molecularly Imprinted Polymer (MIPs) for highly selective alcohol sensors
Advancements in synthesis of Molecularly Imprinted Polymer (MIPs) for highly selective alcohol sensors Open
Highly selective alcohol detection systems are being developed for use in the food, pharmaceutical and clinical industries, as well as for rapidly growing alcohol fuel sector. Several methods, including chromatography, refractometry, and s…
View article: Advancements in electrochemiluminescence-based sensors for ultra-sensitive pesticide residue detection
Advancements in electrochemiluminescence-based sensors for ultra-sensitive pesticide residue detection Open
Pesticides are chemical substances utilized to prevent, control, and eradicate pests or organisms detrimental to crops, playing a pivotal role in minimizing agricultural losses and enhancing yields. However, improper pesticide use can lead…
View article: Cerium oxide nanoparticles-assisted aptasensor for chronic myeloid leukaemia detection
Cerium oxide nanoparticles-assisted aptasensor for chronic myeloid leukaemia detection Open
Background and purpose: Chronic myeloid leukaemia (CML) is one of the most lethal types of leukaemia and can rapidly progress if not treated properly. Therefore, having an effective diagnostic strategy is crucial. Various methods are avail…
View article: Advances in electrochemical biosensors employing carbon-based electrodes for detection of biomarkers in diabetes mellitus
Advances in electrochemical biosensors employing carbon-based electrodes for detection of biomarkers in diabetes mellitus Open
Background and purpose: The increase in diabetes cases has become a major concern in the healthcare sector, necessitating the development of efficient and minimal diagnostic methods. This study aims to provide a comprehensive examination o…
View article: Label-free and label-based electrochemical detection of disease biomarker proteins
Label-free and label-based electrochemical detection of disease biomarker proteins Open
Introduction: Biosensors, analytical devices integrating biological sensing elements with physicochemical transducers, have gained prominence as rapid and convenient tools for monitoring human health status using biochemical analytes. Due …
View article: Recent advances in rapid and reliable biosensors for detection of porcine gelatine
Recent advances in rapid and reliable biosensors for detection of porcine gelatine Open
Gelatine is obtained from the hydrolysis of collagen in bones, skin, fins, fish scales and insect bodies of cattle, pigs, camels, poultry, fish and insects. Consequently, the diversity and availability of gelatine sources, along with gelat…
View article: Identification of CRISPR/Cas12a (Cpf1) guideRNA Sequence Targeting the Mitochondrial DNA D-loop Region in Wild Pig (Sus scrofa) Through Homology Difference and Mismatch Analysis
Identification of CRISPR/Cas12a (Cpf1) guideRNA Sequence Targeting the Mitochondrial DNA D-loop Region in Wild Pig (Sus scrofa) Through Homology Difference and Mismatch Analysis Open
CRISPR (Clustered Regularly Interspaced Short Palindromic Repeat) or CRISPR-associated (Cas) System has become a major gene editing tool. Gene editing with CRISPR requires the Cas protein and the corresponding guide RNA (gRNA). However, lo…
View article: Electrochemical sensors based on the composite of reduced graphene oxide and a multiwalled carbon nanotube-modified glassy carbon electrode for simultaneous detection of hydroquinone, dopamine, and uric acid
Electrochemical sensors based on the composite of reduced graphene oxide and a multiwalled carbon nanotube-modified glassy carbon electrode for simultaneous detection of hydroquinone, dopamine, and uric acid Open
Fabrication of a sensitive electrochemical sensor based on the composite of reduced graphene oxide and multiwalled carbon nanotubes modified glassy carbon electrode for simultaneous measurements of hydroquinone, dopamine, and uric acid.