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View article: Rapid Detection of VREfm Clusters: FTIR Spectroscopy as a Practical Alternative to Whole-Genome Sequencing
Rapid Detection of VREfm Clusters: FTIR Spectroscopy as a Practical Alternative to Whole-Genome Sequencing Open
Vancomycin-resistant Enterococcus faecium (VREfm) has become a significant nosocomial pathogen due to its potential to cause outbreaks. Whole-genome sequencing (WGS) is considered the reference method for determining genomic relatedness am…
View article: Documented vaccination as proof of immunity compared to serology in medical students
Documented vaccination as proof of immunity compared to serology in medical students Open
We analyzed immunity to vaccine-preventable diseases and the predictive value of documented vaccination versus serological results for medical students in Catalonia (Spain). Epidemiological study of antibody seroprevalence and vaccination …
View article: Evaluation of two SARS-CoV-2 whole genome amplification and sequencing workflows for genomic surveillance and outbreak analysis in the clinical microbiology laboratory
Evaluation of two SARS-CoV-2 whole genome amplification and sequencing workflows for genomic surveillance and outbreak analysis in the clinical microbiology laboratory Open
Whole-genome sequencing (WGS) has become a key element of SARS-CoV-2 genomic epidemiology. In Spain and many other countries, this is mostly driven by Illumina-based sequencing, while Oxford Nanopore Tecnologies' MinION Mk1C is a low-cost,…
View article: Durability of the BNT162b2 XBB.1.5-adapted vaccine against JN.1 hospitalisation in Europe, October 2023 to August 2024: A test-negative case-control study using the id.DRIVE platform
Durability of the BNT162b2 XBB.1.5-adapted vaccine against JN.1 hospitalisation in Europe, October 2023 to August 2024: A test-negative case-control study using the id.DRIVE platform Open
Background While multiple studies have shown that the BNT162b2 XBB.1.5-adapted mRNA COVID-19 vaccine (BNT162b2 XBB vaccine) is effective in preventing COVID-19 hospitalisation and death, effectiveness beyond six months remains unexplored. …
View article: Vaccine effectiveness of JCOVDEN single-dose against COVID-19 hospitalisation in Europe: An id.DRIVE test-negative case-control study
Vaccine effectiveness of JCOVDEN single-dose against COVID-19 hospitalisation in Europe: An id.DRIVE test-negative case-control study Open
The JCOVDEN single-dose protected against COVID-19 hospitalisation. It is effective for at least six months, with VE estimates comparatively lower in the older age groups. Results had low to medium levels of certainty and are to be interpr…
View article: P-2050. Ad26.COV2.S (Janssen) COVID-19 Vaccine Effectiveness against Hospitalization in Europe: an id.DRIVE Study
P-2050. Ad26.COV2.S (Janssen) COVID-19 Vaccine Effectiveness against Hospitalization in Europe: an id.DRIVE Study Open
Background Ad26.COV2.S (Janssen COVID-19 Vaccine) is a replication-incompetent viral-vector vaccine used in the international response to the SARS-CoV-2 pandemic. id.DRIVE (previously COVIDRIVE) is a public private partnership that conduct…
View article: Effectiveness of the AZD1222 vaccine against COVID-19 hospitalization in Europe: final results from the COVIDRIVE test-negative case–control study
Effectiveness of the AZD1222 vaccine against COVID-19 hospitalization in Europe: final results from the COVIDRIVE test-negative case–control study Open
Marketing authorization holders of vaccines typically need to report brand-specific vaccine effectiveness (VE) to the regulatory authorities as part of their regulatory obligations. COVIDRIVE (now id. DRIVE) is a European public–private pa…
View article: Effectiveness of the BNT162b2 XBB.1.5-adapted vaccine against COVID-19 hospitalization related to the JN.1 variant in Europe: a test-negative case-control study using the id.DRIVE platform
Effectiveness of the BNT162b2 XBB.1.5-adapted vaccine against COVID-19 hospitalization related to the JN.1 variant in Europe: a test-negative case-control study using the id.DRIVE platform Open
Pfizer.
View article: Dry Wipes for Hygiene in Hospitalized Patients: Economic and Environmental Impact, and Patient and Professional Satisfaction
Dry Wipes for Hygiene in Hospitalized Patients: Economic and Environmental Impact, and Patient and Professional Satisfaction Open
Aims: To compare traditional versus dry wipes hygiene in hospitalized, bedridden patients with regard to economic and environmental impact and patient and professional satisfaction. Background: Evidence shows that dry hygiene with disposab…
View article: Measurement of IFN-γ and IL-2 for the assessment of the cellular immunity against SARS-CoV-2
Measurement of IFN-γ and IL-2 for the assessment of the cellular immunity against SARS-CoV-2 Open
The study of specific T-cell responses against SARS-CoV-2 is important for understanding long-term immunity and infection management. The aim of this study was to assess the dual IFN-γ and IL-2 detection, using a SARS-CoV-2 specific fluore…
View article: Correction: Influenza vaccination coverage and factors associated with severe laboratory-confirmed influenza-related illness in patients receiving care at a tertiary hospital in Catalonia (Spain) during the 2018–2019 epidemic season
Correction: Influenza vaccination coverage and factors associated with severe laboratory-confirmed influenza-related illness in patients receiving care at a tertiary hospital in Catalonia (Spain) during the 2018–2019 epidemic season Open
[This corrects the article DOI: 10.1371/journal.pone.0260397.].
View article: Correlation between Clinical and Immunological Variables and Humoral Response to SARS-CoV-2 Vaccination in Adult Patients with Antibody Deficiency Disorders
Correlation between Clinical and Immunological Variables and Humoral Response to SARS-CoV-2 Vaccination in Adult Patients with Antibody Deficiency Disorders Open
Background. Prophylactic vaccination has proven to be the most effective strategy to fight the COVID-19 pandemic. Methods. This was a prospective observational cohort study involving 30 predominantly antibody deficiency disorders (ADD)-aff…
View article: Relationship between the need for orthodontic treatment and DMFT index in adults
Relationship between the need for orthodontic treatment and DMFT index in adults Open
Introduction: it has been found that subjects with higher DMFT index scores were more likely to require orthodontic treatment. The objective was relationship the need for orthodontic treatment and DMFT index in a population of Paraguayan a…
View article: Relationship between the need for orthodontic treatment and DMFT index in adults
Relationship between the need for orthodontic treatment and DMFT index in adults Open
Introduction: it has been found that subjects with higher DMFT index scores were more likely to require orthodontic treatment. The objective was relationship the need for orthodontic treatment and DMFT index in a population of Paraguayan a…
View article: Measuring T-Cell Responses against SARS-CoV-2 Is of Utility for Disease and Vaccination Management
Measuring T-Cell Responses against SARS-CoV-2 Is of Utility for Disease and Vaccination Management Open
The measurement of specific T-cell responses can be a useful tool for COVID-19 diagnostics and clinical management. In this study, we evaluated the IFN-γ T-cell response against the main SARS-CoV-2 antigens (spike, nucleocapsid and membran…
View article: Evaluation of Fourier Transform Infrared Spectroscopy as a First-Line Typing Tool for the Identification of Extended-Spectrum β-Lactamase-Producing Klebsiella pneumoniae Outbreaks in the Hospital Setting
Evaluation of Fourier Transform Infrared Spectroscopy as a First-Line Typing Tool for the Identification of Extended-Spectrum β-Lactamase-Producing Klebsiella pneumoniae Outbreaks in the Hospital Setting Open
Early detection of pathogen cross-transmission events and environmental reservoirs is needed to control derived nosocomial outbreaks. Whole-genome sequencing (WGS) is considered the gold standard for outbreak confirmation, but, in most cas…
View article: Impact of the Introduction of a Two-Step Laboratory Diagnostic Algorithm in the Incidence and Earlier Diagnosis of Clostridioides difficile Infection
Impact of the Introduction of a Two-Step Laboratory Diagnostic Algorithm in the Incidence and Earlier Diagnosis of Clostridioides difficile Infection Open
Our aim was to determine changes in the incidence of CD infection (CDI) following the introduction of a two-step diagnostic algorithm and to analyze CDI cases diagnosed in the study period. We retrospectively studied CDI (January 2009 to J…
View article: Cultural adaptation, translation and validation of the Spanish version Debriefing Experience Scale
Cultural adaptation, translation and validation of the Spanish version Debriefing Experience Scale Open
Clinical simulation as a teaching methodology allows the student to train and learn technical abilities and/or non-technical abilities. One of the key elements of this teaching methodology is the debriefing, which consists of a conversatio…
View article: Effectiveness of Mental Health Literacy Programs in Primary and Secondary Schools: A Systematic Review with Meta-Analysis
Effectiveness of Mental Health Literacy Programs in Primary and Secondary Schools: A Systematic Review with Meta-Analysis Open
In recent years, there has been an increase in studies evaluating the effectiveness of mental health literacy programs within the context of education as a universal, preventive intervention. A systematic review and meta-analysis regarding…
View article: Psychological impact of the COVID‐19 pandemic on nursing students in the first wave: A cross‐sectional survey
Psychological impact of the COVID‐19 pandemic on nursing students in the first wave: A cross‐sectional survey Open
Aim The aim of the study was to evaluate the psychological impact on nursing students at the end of period of confinement during the first wave of the COVID‐19 outbreak in Spain. Design A cross‐sectional study reported in line with the STR…
View article: Impact of oral health on the quality of life of Paraguayan adults
Impact of oral health on the quality of life of Paraguayan adults Open
Introduction: Alterations in the oral cavity can affect people’s quality of life, hence it is important to determine how the individual perceives their own health. Objective: To determine the oral health-related quality of life in adults w…
View article: Influenza vaccination coverage and factors associated with severe laboratory-confirmed influenza-related illness in patients receiving care at a tertiary hospital in Catalonia (Spain) during the 2018–2019 epidemic season
Influenza vaccination coverage and factors associated with severe laboratory-confirmed influenza-related illness in patients receiving care at a tertiary hospital in Catalonia (Spain) during the 2018–2019 epidemic season Open
Introduction Influenza vaccination rates in risk groups remain suboptimal. Evidence supporting a significant association between influenza vaccination and severe illness is limited. Methods We retrospectively analyzed the epidemiological c…
View article: VP31.02: Mental wellbeing in pregnant women during SARS‐CoV‐2 pandemic
VP31.02: Mental wellbeing in pregnant women during SARS‐CoV‐2 pandemic Open
To determine the effect of SARS-CoV-2 pandemic on maternal mental well-being during pregnancy and its related factors. A multicentric, prospective, population-based study (n = 1,320) including pregnant women consecutively attended during S…
View article: OC15.03: Differential nasopharyngeal microbiota profile of pregnant women with and without SARS‐CoV‐2 infection
OC15.03: Differential nasopharyngeal microbiota profile of pregnant women with and without SARS‐CoV‐2 infection Open
Nasopharyngeal microbiota has been implicated with respiratory infections; however, no previous evidence is reported during SARS-CoV-2 in pregnancy. The aim of this study was to characterise the nasopharyngeal microbiota in pregnant women …
View article: OP03.02: Clinical spectrum of COVID‐19 infection throughout gestation
OP03.02: Clinical spectrum of COVID‐19 infection throughout gestation Open
To describe the clinical presentation of COVID-19 infection throughout gestation in a population-based study. A multicentric, prospective population-based study including pregnant women consecutively attended at first/second trimester or a…
View article: VP31.14: Impact of COVID‐19 infection on pregnancy outcome: a population‐based study
VP31.14: Impact of COVID‐19 infection on pregnancy outcome: a population‐based study Open
To describe the impact of COVID-19 infection throughout gestation on pregnancy outcomes in a population-based study. A multicentric, prospective population-based study including pregnant women consecutively attended at first/second trimest…
View article: Attitudes of Spanish hospital staff towards COVID-19 vaccination and vaccination rates
Attitudes of Spanish hospital staff towards COVID-19 vaccination and vaccination rates Open
Background COVID-19 vaccine hesitancy seems to be universal across countries and subgroups, and so are its determinants. We studied the willingness and factors associated with the decision to be vaccinated against COVID-19 in healthcare wo…