Irfan Rahman
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View article: Analisis Perbandingan Screening Visa Negara Maju Terhadap Negara Rentan
Analisis Perbandingan Screening Visa Negara Maju Terhadap Negara Rentan Open
Penelitian ini bertujuan untuk menganalisis sistem screening visa di Amerika Serikat dan Jepang serta mengevaluasi relevansinya bagi kebijakan calling visa di Indonesia terhadap warga negara dari negara-negara berisiko tinggi. Menggunakan …
View article: Heterogeneity of Cellular Senescence, Senotyping, and Targeting by Senolytics and Senomorphics in Lung Diseases
Heterogeneity of Cellular Senescence, Senotyping, and Targeting by Senolytics and Senomorphics in Lung Diseases Open
Cellular senescence, a state of stable cell cycle arrest accompanied by a complex senescence-associated secretory phenotype (SASP), is a fundamental biological process implicated as a key driver of lung aging and lung age-related diseases …
View article: Single-cell transcriptomics identifies an increased Ly6G- neutrophil population and accentuated T-cell cytotoxicity in tobacco flavored e-cigarette exposed mouse lungs
Single-cell transcriptomics identifies an increased Ly6G- neutrophil population and accentuated T-cell cytotoxicity in tobacco flavored e-cigarette exposed mouse lungs Open
E-cigarettes (e-cigs) are a public health concern for young adults due to their rising popularity despite evidence of harmful effects, i.e. increased oxidative stress and immunotoxicity. Yet an extensive study defining the cell-specific im…
View article: Author response: Single-cell transcriptomics identifies an increased Ly6G- neutrophil population and accentuated T-cell cytotoxicity in tobacco flavored e-cigarette exposed mouse lungs
Author response: Single-cell transcriptomics identifies an increased Ly6G- neutrophil population and accentuated T-cell cytotoxicity in tobacco flavored e-cigarette exposed mouse lungs Open
View article: Health Effects of Delta-8, Delta-9, and Delta-10-Tethydrocannabinol and New Unregulated THC Vaping Products
Health Effects of Delta-8, Delta-9, and Delta-10-Tethydrocannabinol and New Unregulated THC Vaping Products Open
Hemp-derived cannabinoids (CBDs) such as Δ8- and Δ10-tetrahydrocannabinol (THC) in cannabis e-cigarettes have been growing in popularity among youth, causing a great concern for their health effects. Previous novel lung injury outbreaks, n…
View article: Heterogeneity of Cellular Senescence, Senotyping, and Targeting by Senolytics and Senomorphics in Lung Diseases
Heterogeneity of Cellular Senescence, Senotyping, and Targeting by Senolytics and Senomorphics in Lung Diseases Open
Cellular senescence, a state of stable cell cycle arrest accompanied by a complex senescence-associated secretory phenotype (SASP), is a fundamental biological process implicated as a key driver of lung aging and lung age-related diseases …
View article: An Intrinsic-hoc Framework for Heterogeneous Cellular Senescence Elucidation Using Deep Graph Representation Learning and Experimental Validation
An Intrinsic-hoc Framework for Heterogeneous Cellular Senescence Elucidation Using Deep Graph Representation Learning and Experimental Validation Open
Characterizing senescent cells and identifying corresponding senescence-associated genes within complex tissues is critical for our understanding of aging and age-related diseases. We present DeepSAS, an intrinsic-hoc framework for elucida…
View article: AC-DC Cuk Converter: A State-of-the-Art topological review
AC-DC Cuk Converter: A State-of-the-Art topological review Open
AC-DC converters, which transform alternating current (AC) into controlled direct current (DC), are key instruments for systems requiring stable and efficient power conversion. Among various AC-DC topologies, the Cuk converter topology is …
View article: The Efficacy of Clove (Syzygium aromaticum) Decoction in Alleviating Gout Pain in the Elderly: A Systematic Literature Review
The Efficacy of Clove (Syzygium aromaticum) Decoction in Alleviating Gout Pain in the Elderly: A Systematic Literature Review Open
Introduction: Gout pain is a common issue among the elderly, caused by the accumulation of uric acid crystals in the joints, leading to discomfort and limited mobility. Clove (Syzygium aromaticum), known for its anti-inflammatory and analg…
View article: Correction to “Proteomic Analysis of Plasma-Derived Extracellular Vesicles in Smokers and Patients with Chronic Obstructive Pulmonary Disease”
Correction to “Proteomic Analysis of Plasma-Derived Extracellular Vesicles in Smokers and Patients with Chronic Obstructive Pulmonary Disease” Open
[This corrects the article DOI: 10.1021/acsomega.9b00966.].
View article: Single-cell transcriptomics identifies a dampened neutrophil function and accentuated T-cell cytotoxicity in tobacco flavored e-cigarette exposed mouse lungs
Single-cell transcriptomics identifies a dampened neutrophil function and accentuated T-cell cytotoxicity in tobacco flavored e-cigarette exposed mouse lungs Open
E-cigarettes (e-cigs) are a public health concern for young adults due to their popularity and evidence for increased oxidative stress and immunotoxicity. Yet an extensive study defining the cell-specific immune changes upon exposure to fl…
View article: Author response: Single-cell transcriptomics identifies a dampened neutrophil function and accentuated T-cell cytotoxicity in tobacco flavored e-cigarette exposed mouse lungs
Author response: Single-cell transcriptomics identifies a dampened neutrophil function and accentuated T-cell cytotoxicity in tobacco flavored e-cigarette exposed mouse lungs Open
View article: Single-cell transcriptomics identifies a dampened neutrophil function and accentuated T-cell cytotoxicity in tobacco flavored e-cigarette exposed mouse lungs
Single-cell transcriptomics identifies a dampened neutrophil function and accentuated T-cell cytotoxicity in tobacco flavored e-cigarette exposed mouse lungs Open
E-cigarettes (e-cigs) are a public health concern for young adults due to their popularity and evidence for increased oxidative stress and immunotoxicity. Yet an extensive study defining the cell-specific immune changes upon exposure to fl…
View article: Magnetic Resonance Angiography Determined Sex-Related Variations in Configuration of Entire Circle of Willis in Bengali Population of Chattogram Division
Magnetic Resonance Angiography Determined Sex-Related Variations in Configuration of Entire Circle of Willis in Bengali Population of Chattogram Division Open
Background: Magnetic Resonance Angiography (MRA) is a group of techniques based on Magnetic Resonance Imaging (MRI) for imaging of blood vessels. It’s the most widely used method for detecting the morphology of Circle of Willis (COW). By u…
View article: Bioengineering the metabolic network of CAR T cells with GLP-1 and Urolithin A increases persistence and long-term anti-tumor activity
Bioengineering the metabolic network of CAR T cells with GLP-1 and Urolithin A increases persistence and long-term anti-tumor activity Open
Constant tumor antigen exposure disrupts chimeric antigen receptor (CAR) T cell metabolism, limiting their persistence and anti-tumor efficacy. To address this, we develop metabolically reprogrammed CAR (MCAR) T cells with enhanced autopha…
View article: Single-cell transcriptomics identifies altered neutrophil dynamics and accentuated T-cell cytotoxicity in tobacco flavored e-cigarette exposed mouse lungs
Single-cell transcriptomics identifies altered neutrophil dynamics and accentuated T-cell cytotoxicity in tobacco flavored e-cigarette exposed mouse lungs Open
E-cigarettes (e-cigs) are a public health concern for young adults due to their rising popularity despite evidence of harmful effects. Yet an extensive study defining the cell-specific immune changes upon exposure to flavored e-cigs remain…
View article: Altered expression profile of plasma exosomal microRNAs in exclusive electronic cigarette adult users
Altered expression profile of plasma exosomal microRNAs in exclusive electronic cigarette adult users Open
Little is known about how exclusive e-cigarette use affects exosomal microRNA (miRNA) expression, which is crucial in inflammation and disease processes like cancer. We compared exosomal miRNA profiles between exclusive e-cigarette users a…
View article: Genetic diversity leads to differential inflammatory responses to cigarette smoke in mice
Genetic diversity leads to differential inflammatory responses to cigarette smoke in mice Open
The use of genetically diverse mouse models offers a more accurate reflection of human genetic variability, improving the translatability of findings to heterogeneous human populations. This approach is particularly valuable in understandi…
View article: In Vitro assessments of ENDS toxicity in the respiratory tract: Are we there yet?
In Vitro assessments of ENDS toxicity in the respiratory tract: Are we there yet? Open
Approximately 4.6 % of U.S. adults over the age of 18 use e-cigarettes, which are a type of electronic nicotine delivery system (ENDS). Over 2.5 million U.S. middle and high school students also use both disposable and/or flavored ENDS pro…
View article: High-resistance coils in E-cigarettes increase heavy metals leaching into aerosols to cause oxidants generation in human bronchial epithelial cells at air-liquid interface: A unique non-animal methodological approach on vaping studies
High-resistance coils in E-cigarettes increase heavy metals leaching into aerosols to cause oxidants generation in human bronchial epithelial cells at air-liquid interface: A unique non-animal methodological approach on vaping studies Open
View article: Preservation, production, and packaging optimization in SMEs: A study on 'Keripik Lumba-Lumba'
Preservation, production, and packaging optimization in SMEs: A study on 'Keripik Lumba-Lumba' Open
'Keripik Lumba-Lumba' is a Small and Medium-sized Enterprise (SME) that specializes in the production of cassava chips and banana chips. This SME faces several problems such as raw material shrinkage due to shipping, double work, and diffe…
View article: SenSet, a novel human lung senescence cell gene signature, identifies cell-specific senescence mechanisms
SenSet, a novel human lung senescence cell gene signature, identifies cell-specific senescence mechanisms Open
Cellular senescence is a major hallmark of aging. Senescence is defined as an irreversible growth arrest observed when cells are exposed to a variety of stressors including DNA damage, oxidative stress, or nutrient deprivation. While senes…
View article: HIV-1 Tat Protein and Cigarette Smoke Mediated ADAM17 Upregulation Can Lead to Impaired Mucociliary Clearance
HIV-1 Tat Protein and Cigarette Smoke Mediated ADAM17 Upregulation Can Lead to Impaired Mucociliary Clearance Open
Human immunodeficiency virus type-1 (HIV-1) associated comorbidities account for the majority of poor health outcomes in people living with HIV (PLWH) in the era of antiretroviral therapy. Lung-related comorbidities such as chronic obstruc…
View article: A signaling pathway map of plasminogen activator inhibitor-1 (PAI-1/SERPINE-1): a review of an innovative frontier in molecular aging and cellular senescence
A signaling pathway map of plasminogen activator inhibitor-1 (PAI-1/SERPINE-1): a review of an innovative frontier in molecular aging and cellular senescence Open
View article: Dr. Jekyll or Mr. Hyde: The multifaceted roles of miR-145-5p in human health and disease
Dr. Jekyll or Mr. Hyde: The multifaceted roles of miR-145-5p in human health and disease Open
View article: scDOT: optimal transport for mapping senescent cells in spatial transcriptomics
scDOT: optimal transport for mapping senescent cells in spatial transcriptomics Open
The low resolution of spatial transcriptomics data necessitates additional information for optimal use. We developed scDOT, which combines spatial transcriptomics and single cell RNA sequencing to improve the ability to reconstruct single …
View article: Cold ischemia time alters cell-type specific senescence leading to loss of cellular integrity in mouse lungs
Cold ischemia time alters cell-type specific senescence leading to loss of cellular integrity in mouse lungs Open
Purpose: Ischemia-reperfusion injury (IRI) is a major challenge in lung transplantation often causing graft dysfunction and chronic airway illnesses in recipients. To prevent potential transplant related complications, strict guidel…
View article: Caveolin-1 Scaffolding Domain Peptide (CSP7): A Novel Target for Idiopathic Pulmonary Fibrosis
Caveolin-1 Scaffolding Domain Peptide (CSP7): A Novel Target for Idiopathic Pulmonary Fibrosis Open
View article: Altered Host microRNAomics in HIV Infections: Therapeutic Potentials and Limitations
Altered Host microRNAomics in HIV Infections: Therapeutic Potentials and Limitations Open
microRNAs have emerged as essential regulators of health and disease, attracting significant attention from researchers across diverse disciplines. Following their identification as noncoding oligonucleotides intricately involved in post-t…
View article: Toxicity of waterpipe tobacco smoking: the role of flavors, sweeteners, humectants, and charcoal
Toxicity of waterpipe tobacco smoking: the role of flavors, sweeteners, humectants, and charcoal Open
Waterpipe tobacco (WPT) smoking is a public health concern, particularly among youth and young adults. The global spread of WPT use has surged because the introduction of pre-packaged flavored and sweetened WPT, which is widely marketed as…