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View article: Bladder-sparing trimodal therapy in elderly patients with muscle-invasive bladder cancer: a real-world single-center experience
Bladder-sparing trimodal therapy in elderly patients with muscle-invasive bladder cancer: a real-world single-center experience Open
Aim: This study aimed to evaluate survival outcomes and potential prognostic indicators in a real-world cohort of elderly patients diagnosed with early-stage muscle-invasive bladder cancer (MIBC) who underwent trimodal therapy (TMT). Mater…
View article: Efficacy of Perioperative FLOT Therapy in Locally Advanced Gastric Cancer and the Associated Prognostic Factors
Efficacy of Perioperative FLOT Therapy in Locally Advanced Gastric Cancer and the Associated Prognostic Factors Open
Gastric cancer is one of the most common types of cancer.However, despite a significant decrease in the incidence of this cancer over the past two decades, it remains a leading cause of cancer-related deaths worldwide. 1Improved treatment …
View article: The XRCC1 and TP53 gene polymorphisms are associated with advanced-stage disease and early distant metastasis at diagnosis in non-small cell lung cancer
The XRCC1 and TP53 gene polymorphisms are associated with advanced-stage disease and early distant metastasis at diagnosis in non-small cell lung cancer Open
Background: Studies on single nucleotide polymorphisms (SNPs) in non-small cell lung cancer (NSCLC) suggest that DNA repair capacity may have prognostic implications for disease recurrence and survival. However, there is no study investiga…
View article: Evaluation of Attitudes and Behavioral Changes in Relatives of Patients with Breast Cancer
Evaluation of Attitudes and Behavioral Changes in Relatives of Patients with Breast Cancer Open
Objective: The aim of this study was to determine the information and support needs of breast cancer patients’ relatives and to what extent they were met.Methods: This cross-sectional descriptive study was conducted with 177 participants w…
View article: Survival Analysis in Colon Cancer Patients
Survival Analysis in Colon Cancer Patients Open
Introduction: The aim of this study is to investigate the degree of risk and significance of prognostic and demographic factors affecting the survival of patients diagnosed with colon cancer (CC). Material and Method: This was a retrospect…
View article: On Fair Performance Comparison between Random Survival Forest and Cox Regression: An Example of Colorectal Cancer Study
On Fair Performance Comparison between Random Survival Forest and Cox Regression: An Example of Colorectal Cancer Study Open
Random Forest (RF), a mostly model-free and robust machine learning method, has been successfully applied to right-censored survival data, under the name of Random Survival Forest (RSF). However, RF/RSF has its distinct strategies in class…
View article: An Application of Cox Mixed Cure Model for Breast Cancer Patients
An Application of Cox Mixed Cure Model for Breast Cancer Patients Open
Objective: Survival analyses are used in cancer research in the selection of treatment methods that may be effec-tive in survival time and in investigating prognostic factors. In the literature, Cox regression analysis was performed withou…
View article: Evaluation of Death Risks of Lung Cancer Patients with Frailty Models
Evaluation of Death Risks of Lung Cancer Patients with Frailty Models Open
OBJECTIVE:The aim of this study is to investigate the prognostic factors of lung cancer by evaluating the most appropriate survival model with a selection criteria. MATERIAL AND METHODS:In the study, the data of 185 patients diagnosed with…
View article: Prognostic value of the neutrophil-to-lymphocyte ratio and carbohydrate antigen 19-9 in estimating survival in patients with metastatic pancreatic cancer
Prognostic value of the neutrophil-to-lymphocyte ratio and carbohydrate antigen 19-9 in estimating survival in patients with metastatic pancreatic cancer Open
Pretreatment NLR and CA19-9 levels were found to be reliable estimative markers for poor prognosis in patients with metastatic PC. Our findings revealed that NLR and CA19-9 levels can be used to estimate the survival of patients with PC. W…
View article: Prognostic value of the neutrophil-lymphocyte ratio and CA 19-9 in predicting survival inpatients with metastatic pancreatic cancer
Prognostic value of the neutrophil-lymphocyte ratio and CA 19-9 in predicting survival inpatients with metastatic pancreatic cancer Open
Background: The predictive value of different prognostic biomarkers has been studied in various cancer types. The aim of our study is to determine the degree of risk and prognostic significance of the pre-treatment neutrophil-to-lymphocyte…
View article: Survival Analysis in Breast Cancer Patients: Frailty Models
Survival Analysis in Breast Cancer Patients: Frailty Models Open
ÖZET GİRİŞ ve AMAÇ: Meme kanseri hastalarına ait heterojen yaşam verilerinin modellenmesi ve sağkalım süresini etkileyen faktörlerin belirlenmesi