Marta Barradas
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View article: Sexual dimorphism in the antitumor immune responses elicited by the combination of fasting and chemotherapy
Sexual dimorphism in the antitumor immune responses elicited by the combination of fasting and chemotherapy Open
Andrés Pastor Fernández was a recipient of a predoctoral fellowship from the Spanish Association Against Cancer – AECC (PRDMA18011PAST). Cristina Pantoja and Marta Barradas were funded by the Madrid Institute for Advanced Studies (IMDEA) F…
View article: Fatty acids homeostasis during fasting predicts protection from chemotherapy toxicity
Fatty acids homeostasis during fasting predicts protection from chemotherapy toxicity Open
Fasting exerts beneficial effects in mice and humans, including protection from chemotherapy toxicity. To explore the involved mechanisms, we collect blood from humans and mice before and after 36 or 24 hours of fasting, respectively, and …
View article: Fatty acids homeostasis during fasting predicts protection from chemotherapy toxicity
Fatty acids homeostasis during fasting predicts protection from chemotherapy toxicity Open
Fasting exerts beneficial effects in mice and humans, including protection from chemotherapy toxicity. To explore the involved mechanisms, we collect blood from humans and mice before and after 36 or 24 hours of fasting, respectively, and …
View article: Fatty acids homeostasis during fasting predicts protection from chemotherapy toxicity
Fatty acids homeostasis during fasting predicts protection from chemotherapy toxicity Open
Fasting exerts beneficial effects in mice and humans, including protection from chemotherapy toxicity. To explore the involved mechanisms, we collect blood from humans and mice before and after 36 or 24 hours of fasting, respectively, and …
View article: Production of Fucoxanthin from Phaeodactylum tricornutum Using High Performance Countercurrent Chromatography Retaining Its FOXO3 Nuclear Translocation-Inducing Effect
Production of Fucoxanthin from Phaeodactylum tricornutum Using High Performance Countercurrent Chromatography Retaining Its FOXO3 Nuclear Translocation-Inducing Effect Open
Phaeodactylum tricornutum is a rich source of fucoxanthin, a carotenoid with several health benefits. In the present study, high performance countercurrent chromatography (HPCCC) was used to isolate fucoxanthin from an extract of P. tricor…
View article: Conservation of Aging and Cancer Epigenetic Signatures across Human and Mouse
Conservation of Aging and Cancer Epigenetic Signatures across Human and Mouse Open
Aging and cancer are two interrelated processes, with aging being a major risk factor for the development of cancer. Parallel epigenetic alterations have been described for both, although differences, especially within the DNA hypomethylat…
View article: Conservation of aging and cancer epigenetic signatures across human and mouse
Conservation of aging and cancer epigenetic signatures across human and mouse Open
Aging and cancer are two interrelated biological processes, with aging being one of the most important risk factors for the development of cancer. Parallel epigenetic alterations have been described for both, although differences, especial…
View article: Conservation of aging and cancer epigenetic signatures across human and mouse
Conservation of aging and cancer epigenetic signatures across human and mouse Open
Aging and cancer are two interrelated biological processes, with aging being one of the most important risk factors for the development of cancer. Parallel epigenetic alterations have been described for both, although differences, especial…
View article: Transient metabolic improvement in obese mice treated with navitoclax or dasatinib/quercetin
Transient metabolic improvement in obese mice treated with navitoclax or dasatinib/quercetin Open
Senescent cells accumulate with obesity in the white adipose tissue of mice and humans. These senescent cells enhance the pro-inflammatory environment that, with time, contributes to the onset of glucose intolerance and type 2 diabetes. Gl…
View article: Identification and characterization of Cardiac Glycosides as senolytic compounds
Identification and characterization of Cardiac Glycosides as senolytic compounds Open
Compounds with specific cytotoxic activity in senescent cells, or senolytics, support the causal involvement of senescence in aging and offer therapeutic interventions. Here we report the identification of Cardiac Glycosides (CGs) as a fam…